Abstract: The invention provides methods for rapid setting, adjusting, and controlling the temperature of a microfluidic device.

Abstract: A robotic introducer system comprises a first assembly comprising a cable control assembly configured for use in a plurality of medical procedures, a second assembly comprising a distal link extension assembly configured for fewer uses than the first assembly, and a third assembly comprising an articulating probe assembly, coupled between the first and second assemblies and configured for fewer uses than the second assembly.

Abstract: A system for performing a medical procedure is provided comprising at least one tool and a tool support for supporting a distal portion of the tool. An operator manipulates a human interface device and produces control signals sent to a controller. The controller manipulates the tool support based on the received control signals.

Abstract: A system for performing a medical procedure is provided comprising at least one tool and a tool support for supporting a distal portion of the tool. An operator manipulates a human interface device and produces control signals sent to a controller. The controller manipulates the tool support based on the received control signals.

Abstract: A robotic introducer system comprises a first assembly comprising a cable control assembly configured for use in a plurality of medical procedures, a second assembly comprising a distal link extension assembly configured for fewer uses than the first assembly, and a third assembly comprising an articulating probe assembly, coupled between the first and second assemblies and configured for fewer uses than the second assembly.

Abstract: A system for performing a medical procedure is provided comprising at least one tool and a tool support for supporting a distal portion of the tool. An operator manipulates a human interface device and produces control signals sent to a controller. The controller manipulates the tool support based on the received control signals.

Abstract: Herein is disclosed a reinforced catheter system that includes a reinforcement layer including a helical strand, wherein the helical strand has a stiffness of about 30% to about 100% greater than the stiffness of other helical strands used for reinforcing the catheter. The catheter may include a single reinforcement layer or multiple layers. Advantageously, the catheter provides for enhanced kink resistance for navigation of small and/or tortuous vascular channels, and provides enhanced hoop strength for protecting catheter integrity when the device is subjected to increased pressure within its lumen, for example, during the delivery of intravascular agents.

Abstract: A method and device for clot maceration and removal, including inserting a shaft having two lumens into an occluded blood vessel, the shaft having: a guidewire/drug delivery lumen defined partially by a first wall and a thrombus removal lumen defined partially by a second wall. The thrombus removal lumen further defines a skived section where a thrombus may be trapped for removal. A portion of the first wall is coextensive with a portion of the second wall, and the coextensive portion defines at least one hole whereby a drug delivered through the guidewire/drug delivery lumen may pass to the thrombus removal lumen. A maceration device is also disclosed which may be used independently or may be inserted within the guidewire/drug delivery lumen. The maceration device includes: a base wire; a capping plug attached to a distal end of the base wire; a pressure translator slidably attached to the base wire; and a means for maceration coupled between the pressure translator and the capping plug.

Abstract: This invention is a surgical device. In particular, this invention is directed to a multilumen catheter for accessing the vascular system of a body. The multilumen catheter includes a catheter shaft, at least a portion or which includes at least one lumen reinforced with a support member which may include a polymeric or metallic braid, coil or knit material. The reinforced lumen may further include a thin-walled liner or coating of lubricious material. The reinforced lumen may have a circular cross-section adapted to receive a guidewire. The interior surface of the reinforced lumen may have a smooth and continuous surface or a non-uniform surface.