Abstract: A surgical hub may have cooperative interactions with one of more means of displaying the image from the laparoscopic scope and information from one of more other smart devices. The surgical hub may have the capacity of interacting with these multiple displays using an algorithm or control program that enables the combined display and control of the data distributed across the number of displays in communication with the surgical hub. The hub can obtain display control parameter(s) associated with a surgical procedure. The hub may determine, based on the display control parameter, different contents for different displays. The hub may generate and send the display contents to their respective displays. For example, the visualization control parameter may be a progression of the surgical procedure. The surgical hub may determine different display contents for the primary and the secondary displays based on the progression of the surgical procedure.

Abstract: A surgical stapling instrument includes a shaft assembly, an end effector at a distal end of the shaft assembly and having a first jaw with an anvil and a second jaw operable to cooperate with the first jaw to clamp tissue, and a cartridge inserted into the second jaw. The cartridge includes staples, a movable member translatable distally during a firing stroke to discharge the staples into tissue, a first sensor assembly configured to monitor a first condition of the cartridge, and a second sensor assembly configured to monitor a second condition of the cartridge. A first processor is coupled with the first and second sensor assemblies and is configured to receive first and second signals from the sensor assemblies, respectively, where each signal is indicative of the respective condition of the cartridge. The first processor is configured to selectively permit or restrict the firing stroke based upon the signals.

Abstract: A surgical instrument includes a shaft assembly, an end effector, a driving assembly, at least one motor, and a motor controller. The at least one motor is configured to actuate the driving assembly to deploy staples. The motor controller is in communication with the motor. The motor controller is configured to determine whether values of first and second trigger variables exceed predetermined thresholds. The motor controller is configured to modify at least one motor control parameter in response to determining that the values of the first and second trigger variables exceed the predetermined thresholds. The motor control parameters include a motion profile instituted by the motor controller for the motor, a waiting period during which power to the motor is reduced or stopped, or the predetermined threshold relating to current or force for proximal retraction to be different from the predetermined threshold relating to current or force for distal advancement.

Abstract: A surgical system may include tiered-access features. The surgical system may be used to analyze at least a portion of a surgical field. Based on a control parameter, the system may scale up or down various capabilities, such as visualization processing, endocutter communication, endocutter algorithm updates, smart cartridge connectivity, smart motor control for circular stapler, smart energy control, cloud analytics, hub connectivity control, and/or hub visualization and control interactions. The control parameter may include system aspects such as processing capability or bandwidth for example and/or the identification of an appropriate service tier.

Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4A, R4b, and R5, are as defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL.

Abstract: Methods, devices, and systems for controlling a tissue-treatment motion by a surgical instrument are disclosed.

Abstract: A surgical instrument system comprising a motor system and a control circuit is disclosed. The motor system comprises a motor and a drive train movable by the motor to actuate a firing member through a staple firing stroke. The control circuit is coupled to the motor, wherein, during the staple firing stroke, the control circuit is configured to perform a first sensory action to determine if a speed of the motor can be increased to a first target speed, monitor a result of the first sensory action, adjust a parameter of a subsequent sensory action based on the monitored result of the first sensory action, and perform the subsequent sensory action with the adjusted parameter.

Abstract: A surgical stapling system includes an anvil, a blade, a motor and gear assembly, a motor power supply, and a motor controller. A method of controlling the motor includes receiving first and second data indicative of operations of the motor under first and second conditions, respectively, and adjusting a motor control signal based on a difference between the first and second data. Another method includes receiving initial manufacture motor and gear assembly data from a manufacture and operational data during an initial use of the system, and adjusting parameters of the control signal based on a difference between the manufacture data and the operational data. Another method includes controlling a pulse-width modulated (PWM) motor control signal, receiving data regarding an interaction between the blade and a tissue clamped by the anvil, and adjusting a frequency of the PWM signal based on the data related to the interaction.

Abstract: A surgical instrument controls communication capabilities between the surgical instrument and a removeable component. The surgical instrument may determine parameters associated with the surgical instrument and the removable component. Based on the parameters, the surgical instrument determines a level or tier of communication between the surgical instrument and the removable component. The surgical instrument may determine to configure one or more of the following levels: one-way static communication with the component; two-way communication with the component; real-time two-way communication with the component; and communication with a surgical hub.

Abstract: A method for minimizing the life cycle cost of processes such as heating a building. The method utilizes sensors to monitor various pieces of equipment used in the process, for example, boilers, turbines, and the like. The method then performs the steps of identifying a set optimal operating conditions for the process, identifying and measuring parameters necessary to characterize the actual operating condition of the process, validating data generated by measuring those parameters, characterizing the actual condition of the process, identifying an optimal condition corresponding to the actual condition, comparing said optimal condition with the actual condition and identifying variances between the two, and drawing from a set of pre-defined algorithms created using best engineering practices, an explanation of at least one likely source and at least one recommended remedial action for selected variances, and providing said explanation as an output to at least one user.

Abstract: A method for minimizing the life cycle cost of processes such as heating a building. The method utilizes sensors to monitor various pieces of equipment used in the process, for example, boilers, turbines, and the like. The method then performs the steps of identifying a set optimal operating conditions for the process, identifying and measuring parameters necessary to characterize the actual operating condition of the process, validating data generated by measuring those parameters, characterizing the actual condition of the process, identifying an optimal condition corresponding to the actual condition, comparing said optimal condition with the actual condition and identifying variances between the two, and drawing from a set of pre-defined algorithms created using best engineering practices, an explanation of at least one likely source and at least one recommended remedial action for selected variances, and providing said explanation as an output to at least one user.