Abstract: A surgical instrument includes a rotatable electrical coupling assembly having a first part and a second part that electrically couple and rotate relative to each other. The second part is carried by and rotates with a tube collar coupled to a transducer. A portion of the transducer is inserted through an aperture of the second part, but does not contact the second part. The first part of the assembly may electrically couple to the second part via pogo pins, brush contacts, or ball bearings. Alternatively, the first part may comprise conductive channels formed in the casing. The second part may comprise a rotatable drum with a conductive trace. In some versions, one or more components may comprise MID components. In another version, the rotatable electrical coupling assembly comprises a rotatable PC board and brush contact. Further still, a circuit board may be provided with the transducer inside a transducer casing.

Abstract: A compact Raman analysis system combines a near-infrared (NIR) laser source, a 2D array collecting anti-Stokes Raman spectra, and a probe configured to measure complex solid samples, including pharmaceutical tablets and other large-area targets with reduced background fluorescence at relatively low cost. The system collects spectra from an area of 1-mm or greater, preferably 3-12 mm or more, facilitating the collection of statistically useful data from inhomogeneous and laser-sensitive samples, among other applications. Potential pharmaceutical applications include tablet dosage level measurements, as well as online and at-line quality-control (QC) monitoring opportunities. Other applications include tablet identification as a forensic tool to identify counterfeit pharmaceutical products; granulation and blend uniformity for improved formulation via better process understanding.

Abstract: A compact Raman analysis system combines a near-infrared (NIR) laser source, a 2D array collecting anti-Stokes Raman spectra, and a probe configured to measure complex solid samples, including pharmaceutical tablets and other large-area targets with reduced background fluorescence at relatively low cost. The system collects spectra from an area of 1-mm or greater, preferably 3-12 mm or more, facilitating the collection of statistically useful data from inhomogeneous and laser-sensitive samples, among other applications. Potential pharmaceutical applications include tablet dosage level measurements, as well as online and at-line quality-control (QC) monitoring opportunities.

Abstract: A multi-channel, reconfigurable fiber-coupled Raman instrument uses fiber optic switches for laser and calibration light routing to facilitate automated calibration, diagnosis and operational safety. The system allows wavelength axis calibration on all channels; laser wavelength calibration (including multiple and/or backup laser options); fiber coupling optimization; fault detection/diagnosis; and CCD camera binning setup. In the preferred embodiment, dedicated calibration channels surround data channels on a 2-dimensional CCD dispersed slit image implemented using a unique cabling architecture. This “over/under” calibration interpolation approach facilitates quasi-simultaneous or sequential calibration/data acquisitions. CCD binning between sequential calibration and data acquisitions enables higher density multi-channel operation with tilted images based upon a multiplexed grating configuration.

Abstract: An optical configuration suited to the monitoring of a process flow through the wall of a containment vessel for producing a high-quality, high-NA sample focus and reduced residual positive spherical aberration. The invention includes an optical path with a window extending through, and sealed to, the wall of the containment vessel, and an optical surface disposed in the optical path associated with minimizing aberration, increasing numerical aperture, or both. The window has a surface facing into the process flow and a surface facing away from the process flow and, the surface facing away from the process flow is associated with minimizing aberration or increasing numerical aperture. A lens is disposed outside the containment vessel and in the optical path, with the surface of the window facing the lens being substantially spherical. With such an arrangement, the light rays of the optical path are generally normal to the surface of the window facing the lens.

Abstract: An improved optical configuration suited to the monitoring of a process flow through the wall of a containment vessel is capable of producing a high-quality, high-NA sample focus that outperforms current options. One advantage is reduced residual positive spherical aberration to minimize window signal contamination. The invention broadly includes an optical path with a window extending through, and sealed to, the wall of the containment vessel, and an optical surface disposed in the optical path associated with minimizing aberration, increasing numerical aperture, or both. The window has a surface facing into the process flow and a surface facing away from the process flow and, according to one configuration, the surface facing away from the process flow is associated with minimizing aberration or increasing numerical aperture. One optical arrangement includes a lens disposed outside the containment vessel and in the optical path, with the surface of the window facing the lens being substantially spherical.