Patents by Inventor Kevin N. Sill

Kevin N. Sill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY
    Publication number: 20110091534
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 7, 2010
    Publication date: April 21, 2011
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 7893277
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: February 22, 2011
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
    Publication number: 20100324259
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: September 1, 2010
    Publication date: December 23, 2010
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20100292432
    Abstract: The present invention provides block copolymers comprising hydrophobic moieties in a cationic complexing block, methods of preparing the same, and intermediates thereto. The compounds are useful in a variety of applications such as the assembly of micellar polyion complexes. The invention further provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 18, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Gregoire Cardoen, Kevin N. Sill, Janni Mirosevich, Habib Skaff
  • POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER
    Publication number: 20100278932
    Abstract: The present invention provides micelles having SN-38 encapsulated therein.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Adam Carie, Jonathan Rios-Doria, Richard Slama, Gregoire Cardoen
  • POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER
    Publication number: 20100278928
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Jonathan Rios-Doria, Habib Skaff, Gregoire Cardoen
  • POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
    Publication number: 20100280252
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: February 17, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20100278927
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
    Patent number: 7799339
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: September 21, 2010
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • POLYMERIC MICELLES FOR DRUG DELIVERY
    Publication number: 20100159020
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 24, 2010
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
    Publication number: 20100160645
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: May 29, 2009
    Publication date: June 24, 2010
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides
    Publication number: 20100136063
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: June 3, 2010
    Applicants: UNIVERSITY OF SOUTH FLORIDA, INTEZYNE TECHNOLOGIES, INC.
    Inventors: CHUANHAI CAO, XIAOYANG LIN, KURT BREITENKAMP, HABIB SKAFF, KEVIN N. SILL
  • Polymeric micelles for drug delivery
    Patent number: 7638558
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: December 29, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS
    Publication number: 20090286938
    Abstract: The present invention provides polymerization initiators and uses thereof.
    Type: Application
    Filed: April 30, 2009
    Publication date: November 19, 2009
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Gregoire Cardoen, Kurt Breitenkamp
  • Encapsulated amyloid-beta peptides
    Patent number: 7618944
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: November 17, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Habib Skaff, Kevin N. Sill
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 7560588
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: July 14, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • MODIFICATION OF BIOLOGICAL TARGETING GROUPS FOR THE TREATMENT OF CANCER
    Publication number: 20090110662
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 30, 2009
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Jonathan Rios-Doria, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
  • ENCAPSULATED CONTRAST AGENTS
    Publication number: 20090092554
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 9, 2009
    Applicant: Intezyne Technologies, Inc.
    Inventors: Habib Skaff, Kurt Breitenkamp, Kevin N. Sill
  • ENCAPSULATED AMYLOID-BETA PEPTIDES
    Publication number: 20080274965
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: February 29, 2008
    Publication date: November 6, 2008
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Habib Skaff, Kevin N. Sill
  • HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
    Publication number: 20080274173
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin N. SILL, Habib Skaff, Kurt Breitenkamp