Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include an endoscope and a backstop delivery device extendable through the endoscope. The backstop delivery device may deliver a backstop to a location of selected tissue for resection. A backstop may include a covering being deployable in a patient. The covering may have one or more anchoring mechanisms disposed on an edge of the covering. A tissue resecting device may be extendable through the endoscope for resecting the selected tissue for resection. The covering may be deployable to an outer surface of the body lumen, such that the anchoring mechanism may secure the covering to the outer surface of the body lumen and the covering may expand to cover the selected tissue for resection.

Abstract: An endoprosthesis for implantation within a vessel lumen may include a tubular scaffold formed of one or more interwoven filaments, wherein the tubular scaffold is configured to shift between a radially collapsed configuration and a radially expanded configuration, a polymeric covering secured to the tubular scaffold, and an anti-migration element extending radially outward from the tubular scaffold. The anti-migration element extends helically along at least a portion of the length of the tubular scaffold in a first helical direction. The anti-migration element may include a wire extending along an outer surface of the tubular scaffold. The anti-migration element may include a second polymeric covering disposed over the wire.

Abstract: Example expandable stent designs are disclosed. An example expandable stent includes a tubular scaffold including an inner surface, an outer surface and a lumen extending therein. The expandable stent also includes an outer layer disposed along the outer surface of the tubular scaffold and a first preformed flap attached to the outer layer. Additionally, the preformed flap is configured to releasably engage a vessel wall when the stent is implanted therein.

Abstract: A stent includes an elongated tubular member expandable from a radially collapsed configuration to a radially expanded configuration, the elongate tubular member including a first plurality of filaments extending in a first helical direction and a second plurality of filaments extending in a second helical direction, the first plurality of filaments extending in the first helical direction and the second plurality of filaments extending in the second helical direction overlapping to form a plurality of cells arranged in rows extending circumferentially about the elongated tubular member. At least some of the cells within one or more rows are adapted to provide increased flexibility to the stent.

Abstract: A device may include an elongated housing formed of an optically transparent material, the housing extending from a proximal end to a distal end and including a lateral wall extending from the proximal end to a distal tip of the housing, the housing defining a lumen extending into the housing from a proximal opening in the proximal end of the housing. The device also may include a first port extending through the lateral wall of the housing to open the lumen of the housing to an exterior of the housing, the first port being sized and shaped to receive therein a target portion of tissue to be inspected and/or treated.

Abstract: Example medical devices, including example stents and stent systems, are disclosed. An example stent includes an expandable tubular scaffold having a proximal end and a distal end, a first wire coupled to the tubular scaffold, wherein the first wire is shaped into a first coil. The example stent also includes a sensor electrically coupled to the first wire, wherein the sensor is inductively powered by a magnetic field passing through the first wire.

Abstract: The present disclosure relates generally to devices and methods for full thickness tissue resection of an organ (e.g., intestine). In some embodiments, a device includes a conduit, and a plurality of arms rotatably coupled to the conduit. Each of the plurality of arms is movable between a collapsed position and an expanded position, wherein the plurality of arms extends radially outward from the conduit in the expanded position. The device may further include an electrocautery wire coupled to each of the plurality of arms, the electrocautery wire positioned directly adjacent an exterior tissue wall when the plurality of arms is in the expanded position. The device may be advanced back in towards a lumen of the organ until a targeted section of tissue is cut by the electrocautery wire and removed.

Abstract: A control handle for use with a suture device operable through an endoscope includes a grip attachment configured to be secured to an endoscope and a control housing operably secured to the grip attachment. A catheter housing is moveably disposed within the control housing and adapted to releasably secure the suture catheter such that translation of the catheter housing causes translation of the suture catheter. A lever is rotatably securable relative to the catheter housing such that rotation of the lever relative to the catheter housing causes the catheter housing to move relative to the control housing. A sliding tab is disposed relative to the lever such that movement of the sliding tab relative to the lever causes the suture catheter to translate relative to the control wire disposed within the suture catheter.

Abstract: A suture assembly includes a translation assembly that is axially translatable within a working channel of an endoscope and is adapted to releasably secure and/or release a needle and a distal end cap that is securable to an end of the endoscope and is adapted to releasably secure and/or release the needle in order to pass the needle back and forth between the translation assembly and the distal cap. An attachment mechanism configured to releasably secure the distal endcap to an end of the endoscope.

Abstract: A suture assembly may include a needle having a cylindrical body with a sharp point on at least one end, a lumen extending transverse to a longitudinal axis of the cylindrical body, and a recess in communication with an opening to the lumen. A suture extends through the lumen and is secured within the recess of the needle by a sleeve extending over the needle.

Abstract: A suture assembly includes a translation assembly that is axially translatable within a working channel of an endoscope and is adapted to releasably secure and/or release a needle and a distal end cap that is securable to an end of the endoscope and is adapted to releasably secure and/or release the needle in order to pass the needle back and forth between the translation assembly and the distal cap. An attachment mechanism configured to releasably secure the distal endcap to an end of the endoscope.

Abstract: The present disclosure is directed to a method of determining a position of a medical instrument. The method may include inserting a first material into a body and adjacent to the medical instrument, analyzing at least one characteristic of the inserted first material, and determining the position of the medical instrument based on the analysis of the at least one characteristic.

Abstract: A tissue grasping device for use with an endoscope may include a sheath, a control wire slidably disposed within the sheath, and a helical coil disposed over and attached to the control wire. The helical coil may include a proximal region in which adjacent windings are in contact, and a distal region in which adjacent windings are spaced apart. The helical coil may have a sharpened distal tip.

Abstract: A device includes a handle having a trigger in combination with a distal portion, the distal portion including a rigid elongated hollow member which receives tissue therein and a plunger fitted with and configured to slide longitudinally within the hollow member to induce suction at a distal end of the hollow member as the plunger is moved proximally within the hollow member. The trigger is hingedly coupled to the plunger so that pulling the trigger slides the plunger proximally with respect to the hollow member to generate suction to draw the tissue into the distal end of the hollow member. The device further includes a tissue treatment mechanism for encircling the tissue received at the distal end of the hollow member.

Abstract: A device may include an elongated housing formed of an optically transparent material, the housing extending from a proximal end to a distal end and including a lateral wall extending from the proximal end to a distal tip of the housing, the housing defining a lumen extending into the housing from a proximal opening in the proximal end of the housing. The device also may include a first port extending through the lateral wall of the housing to open the lumen of the housing to an exterior of the housing, the first port being sized and shaped to receive therein a target portion of tissue to be inspected and/or treated.

Abstract: A suture assembly may include a needle having a cylindrical body with a sharp point on at least one end, a lumen extending transverse to a longitudinal axis of the cylindrical body, and a recess in communication with an opening to the lumen. A suture extends through the lumen and is secured within the recess of the needle by a sleeve extending over the needle.

Abstract: A suture assembly includes a translation assembly that is axially translatable within a working channel of an endoscope and is adapted to releasably secure and/or release a needle and a distal end cap that is securable to an end of the endoscope and is adapted to releasably secure and/or release the needle in order to pass the needle back and forth between the translation assembly and the distal cap. An attachment mechanism configured to releasably secure the distal endcap to an end of the endoscope.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices, systems and methods to endoscopically suture or otherwise manipulate tissues, organs and/or structures within a body of a patient.

Abstract: A control handle for use with a suture device operable through an endoscope includes a grip attachment configured to be secured to an endoscope and a control housing operably secured to the grip attachment. A catheter housing is moveably disposed within the control housing and adapted to releasably secure the suture catheter such that translation of the catheter housing causes translation of the suture catheter. A lever is rotatably securable relative to the catheter housing such that rotation of the lever relative to the catheter housing causes the catheter housing to move relative to the control housing. A sliding tab is disposed relative to the lever such that movement of the sliding tab relative to the lever causes the suture catheter to translate relative to the control wire disposed within the suture catheter.

Abstract: The present disclosure relates generally to devices and methods for full thickness tissue resection of an organ (e.g., intestine). In some embodiments, a device includes a conduit, and a plurality of arms rotatably coupled to the conduit. Each of the plurality of arms is movable between a collapsed position and an expanded position, wherein the plurality of arms extends radially outward from the conduit in the expanded position. The device may further include an electrocautery wire coupled to each of the plurality of arms, the electrocautery wire positioned directly adjacent an exterior tissue wall when the plurality of arms is in the expanded position. The device may be advanced back in towards a lumen of the organ until a targeted section of tissue is cut by the electrocautery wire and removed.