Patents by Inventor Khadija Schwach-Abdellaoui
Khadija Schwach-Abdellaoui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150190420Abstract: The present invention relates to methods of producing a homogenous hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with divinylsulfone (DVS), said method comprising the steps of (a) providing an alkaline solution of hyaluronic acid, or salt thereof; (b) adding DVS to the solution of step (a), whereby the hyaluronic acid, or salt thereof, is crosslinked with the DVS to form a gel; (c) treating the gel of step (b) with a buffer, wherein the gel swells and forms a hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with DVS.Type: ApplicationFiled: January 7, 2015Publication date: July 9, 2015Inventors: Fanny Longin, Khadija Schwach-Abdellaoui
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Patent number: 8877223Abstract: The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A-O—(CHR1CHR2O)n—B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [—CH(CH3)—COO—] and (ii) glycolide units [—CH2—COO—] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C1-6-alkyl or hydroxy protecting groups, one of R1 and R2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [—(CHR1CHR2O)—] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.Type: GrantFiled: March 7, 2007Date of Patent: November 4, 2014Assignee: Coloplast A/SInventors: Jakob Vange, Khadija Schwach-Abdellaoui, Hanne Everland, Peter Sylvest Nielsen, Brian Nielsen, Lene Karin Jespersen, Lene Feldskov Nielsen
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Publication number: 20130338100Abstract: The present invention relates to methods of producing a homogenous hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with divinylsulfone (DVS), said method comprising the steps of (a) providing an alkaline solution of hyaluronic acid, or salt thereof; (b) adding DVS to the solution of step (a), whereby the hyaluronic acid, or salt thereof, is crosslinked with the DVS to form a gel; (c) treating the gel of step (b) with a buffer, wherein the gel swells and forms a hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with DVS.Type: ApplicationFiled: June 7, 2013Publication date: December 19, 2013Inventors: Fanny Longin, Khadija Schwach-Abdellaoui
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Patent number: 8481080Abstract: The present invention relates to methods of producing a homogenous hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with divinylsulfone (DVS), said method comprising the steps of (a) providing an alkaline solution of hyaluronic acid, or salt thereof; (b) adding DVS to the solution of step (a), whereby the hyaluronic acid, or salt thereof, is crosslinked with the DVS to form a gel; (c) treating the gel of step (b) with a buffer, wherein the gel swells and forms a hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with DVS.Type: GrantFiled: November 24, 2005Date of Patent: July 9, 2013Assignee: Novozymes Biopolymer A/SInventors: Fanny Longin, Khadija Schwach-Abdellaoui
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Patent number: 8202986Abstract: A branched hyaluronic acid, wherein the linear backbone comprises hyaluronic acid in which one or more N-Acetyl-Glucosamine has been deacetylated to Glucosamine, with branching sidechain(s) covalently linked to the primary amine(s) of said deacetylated Glucosamine thus forming a secondary amine(s); a precursor for producing said branched hyaluronic acid; and a method for producing said branching hyaluronic acid.Type: GrantFiled: July 13, 2007Date of Patent: June 19, 2012Assignee: Novozymes Biopolymer AISInventors: Kristoffer Toemmeraas, Khadija Schwach-Abdellaoui
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Publication number: 20100210588Abstract: The invention concerns a product comprising hyaluronic acid or a salt thereof, wherein the hyaluronic acid has been partially or fully linked or crosslinked with a polymer of an alpha hydroxy acid. The invention also concerns manufacture of the product, uses of the product of the invention in the field of biodegradable plastic materials for the preparation of sanitary and surgical articles, in the pharmaceutical and cosmetic fields; including the various articles made with the same in such fields.Type: ApplicationFiled: March 12, 2010Publication date: August 19, 2010Applicant: Novozymes BioPolymer A/SInventors: Khadija Schwach-Abdellaoui, Michel Vert, Laurent Pravata
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Publication number: 20090312283Abstract: A branched hyaluronic acid, wherein the linear backbone comprises hyaluronic acid in which one or more N-Acetyl-Glucosamine has been deacetylated to Glucosamine, with branching sidechain(s) covalently linked to the primary amine(s) of said deacetylated Glucosamine thus forming a secondary amine(s); a precursor for producing said branched hyaluronic acid; and a method for producing said branching hyaluronic acidType: ApplicationFiled: July 13, 2007Publication date: December 17, 2009Applicant: Novozymes Biopolymer A/SInventors: Kristoffer Toemmeraas, Khadija Schwach-Abdellaoui
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Publication number: 20090155362Abstract: The present invention relates to methods of producing a homogenous hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with divinylsulfone (DVS), said method comprising the steps of (a) providing an alkaline solution of hyaluronic acid, or salt thereof; (b) adding DVS to the solution of step (a), whereby the hyaluronic acid, or salt thereof, is crosslinked with the DVS to form a gel; (c) treating the gel of step (b) with a buffer, wherein the gel swells and forms a hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with DVS.Type: ApplicationFiled: November 24, 2005Publication date: June 18, 2009Applicant: NOVOZYMES BIOPOLYMERInventors: Fanny Longin, Khadija Schwach-Abdellaoui
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Publication number: 20090047322Abstract: The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A—O—(CHR1CHR2O)n-B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [—CH(CH3)—COO—] and (ii) glycolide units [—CH2—COO—] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C1-6-alkyl or hydroxy protecting groups, one of R1 and R2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [-(CHR1CHR2O)—] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.Type: ApplicationFiled: March 7, 2007Publication date: February 19, 2009Inventors: Jakob Vange, Khadija Schwach-Abdellaoui, Hanne Everland, Peter Sylvest Nielsen, Brian Nielsen, Lene Karin Jespersen, Lene Feldskov Nielsen
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Publication number: 20080274999Abstract: A moisturizing, cosmetic, or anti-wrinkle product comprising hyaluronic acid or a salt thereof, wherein the hyaluronic acid or salt thereof has an average molecular weight in the range of 0.7-0.9 MDa, compositions comprising said product, and uses of said product.Type: ApplicationFiled: December 22, 2005Publication date: November 6, 2008Applicant: Novozymes Biopolymer A/SInventors: Khadija Schwach Abdellaoui, Soren Halbye
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Publication number: 20080182982Abstract: The present invention relates to a method of producing methyl esters of a hyaluronic acid, said method comprising the steps of: (a) providing a suspension comprising the acid form of the hyaluronic acid in methanol; (b) adding an organic solution of trimethylsilyldiazomethane to the suspension and mixing, whereby methyl esters of hyaluronic acid are produced; and (c) recovering the hyaluronic acid methyl esters.Type: ApplicationFiled: January 23, 2008Publication date: July 31, 2008Applicant: Novozymes Biolpolymer A/SInventors: Vineer Kumar, Fanny Longin, Khadija Schwach-Abdellaoui, Richard A. Gross
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Publication number: 20080139501Abstract: The invention concerns a product comprising hyaluronic acid or a salt thereof, wherein the hyaluronic acid has been partially or fully linked or crosslinked with a polymer of an alpha hydroxy acid. The invention also concerns manufacture of the product, uses of the product of the invention in the field of biodegradable plastic materials for the preparation of sanitary and surgical articles, in the pharmaceutical and cosmetic fields; including the various articles made with the same in such fields.Type: ApplicationFiled: December 23, 2005Publication date: June 12, 2008Applicant: Novozymes BioPolymer A/SInventors: Khadija Schwach Abdellaoui, Michel Vert, Laurent Pravata
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Publication number: 20050147715Abstract: The present invention relates to a method for improving the textural properties of a dairy product by using a combination of hyaluronic acid and a second texturizing agent for producing the dairy product, and to a dairy product comprising hyaluronic acid and a second texturizing agent.Type: ApplicationFiled: December 17, 2004Publication date: July 7, 2005Applicants: Novozymes Biopolymer A/S, Christian Hansen A/SInventors: Khadija Schwach-Abdellaoui, Jorgen Thorball, Rikke Joergensen
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Publication number: 20050147732Abstract: The present invention relates to a method for improving the textural properties of a non-dairy food product by using a combination of hyaluronic acid and a second texturizing agent for producing the food product.Type: ApplicationFiled: December 17, 2004Publication date: July 7, 2005Applicant: Novozymes Biopolymer A/SInventors: Khadija Schwach-Abdellaoui, Jorgen Thorball, Rikke Joergensen