Patents by Inventor Khosrow Kashfi

Khosrow Kashfi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NO- and HS-releasing compounds
    Patent number: 10450260
    Abstract: This disclosure relates to compounds containing both an NO-releasing moiety and an H2S-releasing moiety and the use of such compounds in treating inflammatory diseases, including cancers.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: October 22, 2019
    Assignee: Research Foundation of The City University of New York
    Inventors: Khosrow Kashfi, Ravinder Kodela
  • Method of priming plants against abiotic stress factors
    Patent number: 10071981
    Abstract: A method of reducing cellular damage to a plant by treating the plant with a compound containing an NO-releasing moiety and an H2S-releasing moiety covalently bonded to an aspirin derived core or a NOSH compound is claimed. The compounds may also be used in a method of priming a plant against abiotic stress factors and a method of promoting plant growth.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: September 11, 2018
    Assignees: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK, CYPRUS UNIVERSITY OF TECHNOLOGY
    Inventors: Khosrow Kashfi, Vasileios Fotopoulos
  • NSAIDs derivatives and uses thereof
    Patent number: 10023555
    Abstract: The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use of the NSAID derivatives in treating inflammatory diseases and pharmaceutical compositions thereof.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: July 17, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Khosrow Kashfi, Mitali Chattopadhyay, Ravinder Kodela
  • NO- AND H2S- RELEASING COMPOUNDS
    Publication number: 20170260124
    Abstract: This disclosure relates to compounds containing both an NO-releasing moiety and an H2S-releasing moiety and the use of such compounds in treating inflammatory diseases, including cancers.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 14, 2017
    Inventors: Khosrow Kashfi, Ravinder Kodela
  • No- and HS-releasing compounds
    Patent number: 9688607
    Abstract: This disclosure relates to novel compounds containing an H2S releasing moiety and a nitric oxide (NO) releasing moiety covalently linked with a core (e.g., a salicylic acid moiety) and the use of such compounds in treating inflammatory diseases, including cancers. Therapeutic potency of these compounds is significantly higher than NSAIDs containing a H2S-releasing moiety alone (HS-NSAIDs) and NSAID containing a NO-releasing moiety alone (NO-NSAIDs). The compounds, in addition, exhibit reduced side effect, e.g., reduced stomach ulcers, upon administration.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: June 27, 2017
    Assignee: Research Foundation of The City University of New York
    Inventors: Khosrow Kashfi, Ravinder Kodela
  • Method of Priming Plants Against Abiotic Stress Factors
    Publication number: 20170174651
    Abstract: A method of reducing cellular damage to a plant by treating the plant with a compound containing an NO-releasing moiety and an H2S-releasing moiety covalently bonded to an aspirin derived core or a NOSH compound is claimed. The compounds may also be used in a method of priming a plant against abiotic stress factors and a method of promoting plant growth.
    Type: Application
    Filed: February 11, 2015
    Publication date: June 22, 2017
    Inventors: Khosrow Kashfi, Vasileios Fotopoulos
  • NSAIDs DERIVATIVES AND USES THEREOF
    Publication number: 20150376162
    Abstract: The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use of the NSAID derivatives in treating inflammatory diseases and pharmaceutical compositions thereof.
    Type: Application
    Filed: February 7, 2014
    Publication date: December 31, 2015
    Applicant: Research Foundation of The City University of New York
    Inventors: Khosrow Kashfi, Mitali Chattopadhyay, Ravinder Kodela
  • NO- AND H2S- RELEASING COMPOUNDS
    Publication number: 20140221316
    Abstract: This disclosure relates to novel compounds containing an H2S releasing moiety and a nitric oxide (NO) releasing moiety covalently linked with a core (e.g., a salicylic acid moiety) and the use of such compounds in treating inflammatory diseases, including cancers. Therapeutic potency of these compounds is significantly higher than NSAIDs containing a H2S-releasing moiety alone (HS-NSAIDs) and NSAID containing a NO-releasing moiety alone (NO-NSAIDs). The compounds, in addition, exhibit reduced side effect, e.g., reduced stomach ulcers, upon administration.
    Type: Application
    Filed: August 15, 2012
    Publication date: August 7, 2014
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Khosrow Kashfi, Ravinder Kodela
  • Compounds and compositions for treating dysproliferative diseases, and methods of use thereof
    Patent number: 7585997
    Abstract: Compounds are disclosed with activity towards killing dysproliferative cells in vitro and treating cancer in vivo. Cancers such as cancer of the colon, pancreas, prostate, lung, breast, urinary bladder, skin and liver are exemplary. Compounds, pharmaceutical compositions and methods of use are described.
    Type: Grant
    Filed: December 31, 2004
    Date of Patent: September 8, 2009
    Assignee: Chesterford Enterprises Limited
    Inventor: Khosrow Kashfi
  • Compounds and compositions for treating dysproliferative diseases, and methods of use thereof
    Publication number: 20050182134
    Abstract: Compounds are disclosed with activity towards killing dysproliferative cells in vitro and treating cancer in vivo. Cancers such as cancer of the colon, pancreas, prostate, lung, breast, urinary bladder, skin and liver are exemplary. Compounds, pharmaceutical compositions and methods of use are described.
    Type: Application
    Filed: December 31, 2004
    Publication date: August 18, 2005
    Inventor: Khosrow Kashfi