Patents by Inventor Kim L. Kanki

Kim L. Kanki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conditional knockout method for gene trapping and gene targeting using an inducible gene silencer
    Patent number: 7625755
    Abstract: A method for conditionally knocking out and altering gene function and genetic sequences that can be used in such methods, for use in gene trapping and gene targeting. Specifically, the genetic sequence is a inducible gene silencer comprising: (a) a splice acceptor sequence; (b) an internal ribosomal entry site (IRES) sequence; (c) a nucleotide sequence coding for a reporter protein; (d) a polyadenylation sequence; and (e) a pair of oppositely oriented recombination site sequences, which cause single cycle inversions in the presence of a suitable recombinase enzyme, flanking elements (a) through (d).
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: December 1, 2009
    Assignee: Wyeth
    Inventors: G. Roger Askew, Kim L. Kanki
  • Conditional knockout method for gene trapping and gene targeting using an inducible gene silencer
    Publication number: 20040241851
    Abstract: A method for conditionally knocking out and altering gene function and genetic sequences that can be used in such methods, for use in gene trapping and gene targeting. Specifically, the genetic sequence is a inducible gene silencer comprising: (a) a splice acceptor sequence; (b) an internal ribosomal entry site (IRES) sequence; (c) a nucleotide sequence coding for a reporter protein; (d) a polyadenylation sequence; and (e) a pair of oppositely oriented recombination site sequences, which cause single cycle inversions in the presence of a suitable recombinase enzyme, flanking elements (a) through (d).
    Type: Application
    Filed: May 30, 2003
    Publication date: December 2, 2004
    Applicant: Wyeth
    Inventors: G. Roger Askew, Kim L. Kanki