Patents by Inventor Kim R. Folger-Bruce

Kim R. Folger-Bruce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of chimeric antibodies by homologous recombination
    Patent number: 5482856
    Abstract: A process for producing chimeric antibodies using novel recombinant DNA vectors and homologous recombination in vivo is described. The recombinant DNA constructs of the invention can be used to transfect antibody producing cells so that targeted homologous recombination occurs in the transfected cells leading to gene modification and the production of chimeric antibody molecules by the transfected cells.
    Type: Grant
    Filed: April 12, 1993
    Date of Patent: January 9, 1996
    Assignee: Oncogen Inc.
    Inventors: H. Perry Fell, Jr., Kim R. Folger-Bruce, Susan M. Yarnold
  • Production of chimeric antibodies by homologous recombination
    Patent number: 5204244
    Abstract: A process for producing chimeric antibodies using novel recombinant DNA vectors and homologous recombination in vivo is described. The recombinant DNA constructs of the invention can be used to transfect antibody producing cells so that targeted homologous recombination occurs in the transfected cells leading to gene modification and the production of chimeric antibody molecules by the transfected cells.
    Type: Grant
    Filed: September 14, 1988
    Date of Patent: April 20, 1993
    Assignee: Oncogen
    Inventors: H. Perry Fell, Kim R. Folger Bruce
  • Production of chimeric antibodies by homologous recombination
    Patent number: 5202238
    Abstract: A process for producing chimeric antibodies using novel recombinant DNA vectors and homologous recombination in vivo is described. The recombinant DNA constructs of the invention can be used to transfect antibody producing cells so that targeted homologous recombination occurs in the transfected cells leading to gene modification and the production of chimeric antibody molecules by the transfected cells.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: April 13, 1993
    Assignee: Oncogen
    Inventors: H. Perry Fell, Jr., Kim R. Folger-Bruce