Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as activators from AMPK, pharmaceutical compositions containing such compounds and their use to treat, for example, heart failure or peripheral vascular disease.

Abstract: A hermetic seal for electrochemical cells. The seal is formed between first and second electronically conductive barrier members. The seal is formed by a cold weld between the first and second barrier members. At least one of the first barrier member and the second barrier member are configured to function as current collectors.

Abstract: A method and apparatus for concentrating diverse input signals indicative of the state or magnitude of a variety of functions and conditions of an engine-driven watercraft is disclosed. A power regulation portion includes a feedback resistor configured to form a hysteresis loop to prevent operation in a linear region when an over voltage condition exists, thus protecting the circuitry from excessive power dissipation. The apparatus also includes a reverse voltage protection circuit including a diode and a polyswitch that protects downstream circuits from application of reverse polarity power. An inventive method for determining the speed of the watercraft, using a measured pressure, and which includes a calculated component designed to account for the effects of the friction as in a pitot tube is disclosed. An input is obtained from a user-actuated switch, such input being used to vary an adjustment factor, which in turn varies the watercraft speed determination using the inventive speed method.

Abstract: A method and an apparatus are provided for displaying a value of a measured parameter for an engine-driven vehicle, such as the speed of an engine. The apparatus includes a microcontroller which receives a data signal from a data concentrator. The data signal contains information relating to the value of a parameter which has been measured by a sensor or other measuring device. Based on the value of the data signal the microcontroller generates one or more motor control signals. The motor control signals are used to drive a stepper-motor. The motor rotates an output shaft which has a pointer mounted near one end of the shaft. The angular position of the output shaft upon rotation corresponds to the value of the parameter and the pointer helps to provide a human-readable format for the parameter value.

Abstract: A distributorless ignition system is shown having a timing controller that is responsive to one cylinder of the engine reaching top dead center for predicting the times at which one or more subsequent cylinders in the firing order should enter dwell and fire based upon the current engine speed, current battery voltage and the time interval between one cylinder reaching top dead center and the preceding cylinder reaching top dead center. At low operating speeds the controller plans for the firing of a cylinder utilizing triple precision calculations. At midrange speeds and high speeds, however, the controller utilizes double precision calculatons. At very high speeds, the controller of the present invention plans the firing of two or more cylinders at the same time forcing the cylinders into overlapping dwell.