Patents by Inventor Kimiko Makino

Kimiko Makino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Remedy
    Patent number: 8425939
    Abstract: It is intended to provide a remedy for diseases caused by macrophages with dysfunction or mediated by macrophages. Namely, a remedy which activates the phagocytic capacity of macrophages and thus is efficiently incorporated into the macrophages due to the vigorous phagocytosis. As a result, the macrophages with dysfunction are normalized, macrophages infected with a pathogen are exterminated or a pathogen in the infected macrophages is exterminated.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: April 23, 2013
    Inventors: Hiroshi Terada, Kimiko Makino, Gen-Ichiro Soma
  • Iontophoretic preparation for treatment of breast cancer and/or mastitis
    Patent number: 8362027
    Abstract: The present invention is to provide means to treat breast cancer and/or mastitis by topically administering a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent and allowing them efficiently to arrive into the mammary gland. The present invention provides an iontophoretic preparation for treating breast cancer and/or mastitis which contains a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent as an active ingredient and has a donor to be applied on a nipple part for topical administration of the active ingredient from the nipple part to the mammary gland by application of electric potential.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: January 29, 2013
    Assignees: Kowa Co., Ltd., Tokyo University of Science Educational Foundation Administrative Organization
    Inventors: Toshio Inagi, Makoto Kanebako, Hiroshi Terada, Kimiko Makino, Masakazu Toi
  • Nanocomposite particles
    Patent number: 8343551
    Abstract: Nanocomposite particles having good solubility and redispersibility in water are provided. The nanocomposite particles include a sugar material and nanoparticles containing a drug to be delivered and a biodegradable polymer, the sugar material being disaccharide, and a mass ratio of the nanoparticles to the disaccharide being within the range of from 40:60 to 60:40.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: January 1, 2013
    Assignee: Tokyo University of Science Educational Foundation Administrative Organization
    Inventors: Kimiko Makino, Hiroshi Terada, Takehisa Nakajima, Keishiro Tomoda
  • IONTOPHORETIC PREPARATION FOR TREATMENT OF BREAST CANCER AND/OR MASTITIS
    Publication number: 20110295189
    Abstract: The present invention is to provide means to treat breast cancer and/or mastitis by topically administering a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent and allowing them efficiently to arrive into the mammary gland. The present invention provides an iontophoretic preparation for treating breast cancer and/or mastitis which contains a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent as an active ingredient and has a donor to be applied on a nipple part for topical administration of the active ingredient from the nipple part to the mammary gland by application of electric potential.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 1, 2011
    Applicants: Tokyo Univ. of Sci. Edu. Fdn. Admin. Org., Kowa Co., Ltd.
    Inventors: Toshio INAGI, Makoto Kanebako, Hiroshi Terada, Kimiko Makino, Masakazu Toi
  • Iontophoretic preparation for treatment of breast cancer and/or mastitis
    Patent number: 8034824
    Abstract: The present invention is to provide means to treat breast cancer and/or mastitis by topically administering a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent and allowing them efficiently to arrive into the mammary gland. The present invention provides an iontophoretic preparation for treating breast cancer and/or mastitis which contains a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent as an active ingredient and has a donor to be applied on a nipple part for topical administration of the active ingredient from the nipple part to the mammary gland by application of electric potential.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: October 11, 2011
    Assignees: Kowa Co., Ltd., Tokyo University of Science Educational Foundation Administrative Organization
    Inventors: Toshio Inagi, Makoto Kanebako, Hiroshi Terada, Kimiko Makino, Masakazu Toi
  • Remedy
    Publication number: 20100178354
    Abstract: It is intended to provide a remedy for diseases caused by macrophages with dysfunction or mediated by macrophages. Namely, a remedy which activates the phagocytic capacity of macrophages and thus is efficiently incorporated into the macrophages due to the vigorous phagocytosis. As a result, the macrophages with dysfunction are normalized, macrophages infected with a pathogen are exterminated or a pathogen in the infected macrophages is exterminated.
    Type: Application
    Filed: March 22, 2010
    Publication date: July 15, 2010
    Applicant: TERADA, Hiroshi
    Inventors: Hiroshi Terada, Kimiko Makino, Gen-Ichiro Soma
  • IONTOPHORETIC PREPARATION FOR TREATMENT OF BREAST CANCER AND/OR MASTITIS
    Publication number: 20090281063
    Abstract: The present invention is to provide means to treat breast cancer and/or mastitis by topically administering a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent and allowing them efficiently to arrive into the mammary gland. The present invention provides an iontophoretic preparation for treating breast cancer and/or mastitis which contains a non-steroidal antiinflammatory analgetic agent and/or an anticancer agent as an active ingredient and has a donor to be applied on a nipple part for topical administration of the active ingredient from the nipple part to the mammary gland by application of electric potential.
    Type: Application
    Filed: October 11, 2006
    Publication date: November 12, 2009
    Applicants: KOWA CO., LTD., TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION
    Inventors: Toshio Inagi, Makoto Kanebako, Hiroshi Terada, Kimiko Makino, Masakazu Toi
  • NANOCOMPOSITE PARTICLES
    Publication number: 20090169637
    Abstract: Nanocomposite particles having good solubility and redispersibility in water are provided. The nanocomposite particles include a sugar material and nanoparticles containing a drug to be delivered and a biodegradable polymer, the sugar material being disaccharide, and a mass ratio of the nanoparticles to the disaccharide being within the range of from 40:60 to 60:40.
    Type: Application
    Filed: March 16, 2007
    Publication date: July 2, 2009
    Applicant: TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION
    Inventors: Kimiko Makino, Hiroshi Terada, Takehisa Nakajima, Keishiro Tomoda
  • Remedy
    Publication number: 20060105048
    Abstract: It is intended to provide a remedy for diseases caused by macrophages with dysfunction or mediated by macrophages. Namely, a remedy which activates the phagocytic capacity of macrophages and thus is efficiently incorporated into the macrophages due to the vigorous phagocytosis. As a result, the macrophages with dysfunction are normalized, macrophages infected with a pathogen are exterminated or a pathogen in the infected macrophages is exterminated.
    Type: Application
    Filed: August 27, 2003
    Publication date: May 18, 2006
    Inventors: Hiroshi Terada, Kimiko Makino, Gen-Ichiro Soma