Patents by Inventor Kingman Ng

Kingman Ng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLP-1 Fc FUSION PROTEIN FORMULATION
    Publication number: 20100196405
    Abstract: The invention provides a stable solution formulation comprising a therapeutically effective amount of a GLP-1-Fc fusion protein at about pH 6.5 in citrate buffer with polysorbate-80 and mannitol. The formulation is useful in treating diabetes and obesity as well as a variety of other conditions or disorders.
    Type: Application
    Filed: July 9, 2008
    Publication date: August 5, 2010
    Inventor: Kingman Ng
  • Anti-IL-17 Antibodies
    Publication number: 20080269467
    Abstract: Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.
    Type: Application
    Filed: December 5, 2006
    Publication date: October 30, 2008
    Inventors: Barrett Allan, Chi-Kin Chow, Lihua Huang, Ling Liu, Jirong Lu, Kingman Ng, Jonathan Wendell Tetreault, Andrew Gordon Werner
  • Pre-mixes of GLP-1 and basal insulin
    Patent number: 7238663
    Abstract: The present invention encompasses pre-mixed formulations comprising a GLP-1 polypeptide and a basal insulin.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: July 3, 2007
    Assignee: Eli Lilly and Company
    Inventors: Michael Rosario DeFelippis, Richard Dennis DiMarchi, Kingman Ng
  • Biphasic mixtures of GLP-1 and insulin
    Patent number: 7179788
    Abstract: The present invention encompasses pharmaceutical formulations comprising a biphasic mixture which comprises a glucagon like peptide (GLP-1) compound in a solid phase and an insulin in a solution phase.
    Type: Grant
    Filed: October 7, 2002
    Date of Patent: February 20, 2007
    Assignee: Eli Lilly and Company
    Inventors: Michael Rosario DeFelippis, Richard Dennis DiMarchi, Kingman Ng, Michael Ernst Trautmann
  • GLP-1 formulations with protracted time action
    Patent number: 7144863
    Abstract: The present invention encompasses compositions wherein a GLP-1 compound is complexed with a basic polypeptide. The compositions provide a prolonged duration of action and can be administered by the pulmonary route.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: December 5, 2006
    Assignee: Eli Lilly and Company
    Inventors: Michael Rosario DeFelippis, Henry Acken Havel, Kenneth F. Mace, Kingman Ng, Virender Kumar Sarin
  • Glp-1 formulations with protracted time action
    Publication number: 20050043228
    Abstract: The present invention encompasses compositions wherein a GLP-1 compound is complexed with a basic polypeptide. The compositions provide a prolonged duration of action and can be administered by the pulmonary route.
    Type: Application
    Filed: May 21, 2002
    Publication date: February 24, 2005
    Inventors: Michael DeFelippis, Henry Havel, Kenneth Mace, Kingman Ng, Virender Sarin
  • Insulin molecule having protracted time action
    Publication number: 20050014679
    Abstract: The present invention provides an insulin molecule that provides a protracted, even basal duration of action. The insulin molecule comprises a modification at the N-terminus of the A-chain, optionally a modification at the N-terminus of the B-chain, a modification at a B-chain lysine, and optionally a modification at the C-terminus of the A-chain. The present invention also provides a method of treating diabetes mellitus comprising administering the insulin molecule.
    Type: Application
    Filed: December 12, 2002
    Publication date: January 20, 2005
    Inventors: John Beals, Michael DeFelippis, Richard DiMarchi, Wayne Kohn, Radmila Micanovic, Sharon Myers, Kingman Ng, Lianshan Zhang
  • Biphasic mixtures of glp-1 and insulin
    Publication number: 20040254107
    Abstract: The present invention encompasses pharmaceutical formulations comprising a biphasic mixture which comprises a glucagon like peptide (GLP-1) compound in a solid phase and an insulin in a solution phase.
    Type: Application
    Filed: March 19, 2004
    Publication date: December 16, 2004
    Inventors: Michael Rosario DeFelippis, Richard Dennis DiMarchi, Kingman Ng, Michael Ernst Trautmann
  • Pre-mixes of glp-1 and basal insulin
    Publication number: 20040235710
    Abstract: The present invention encompasses pre-mixed formulations comprising a GLP-1 polypeptide and a basal insulin.
    Type: Application
    Filed: February 9, 2004
    Publication date: November 25, 2004
    Inventors: Michael Rosario DeFelippis, Richard Dennis DiMarchi, Kingman Ng