Patents by Inventor Kinuko Nagamine

Kinuko Nagamine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing lymphocytes
    Patent number: 8765469
    Abstract: A method for preparing lymphocytes characterized in that the method comprises the step of carrying out expansion in the presence of (a) fibronectin, a fragment thereof or a mixture thereof, (b) a CD3 ligand, and (c) a CD28 ligand.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: July 1, 2014
    Assignee: Takara Bio Inc.
    Inventors: Takahiro Marui, Kinuko Nagamine, Nobuko Muraki, Akiko Kato, Tatsuji Enoki, Hiroaki Sagawa, Ikunoshin Kato
  • Method of producing lymphocytes
    Patent number: 8216837
    Abstract: A method of producing lymphocytes characterized by comprising the step of culturing lymphocytes in the presence of a modified recombinant fibronectin fragment which has overlapping parts of the heparin-binding domain of fibronectin. This method makes it possible to achieve a high cell proliferation rate. The lymphocytes obtained thereby are appropriately usable in, for example, adoptive immunotherapy and, therefore, expected as highly useful in the clinical field. Moreover, a novel modified recombinant fibronectin fragment is provided.
    Type: Grant
    Filed: June 7, 2007
    Date of Patent: July 10, 2012
    Assignee: Takara Bio Inc.
    Inventors: Nobuko Muraki, Mitsuko Ideno, Kinuko Nagamine, Fuyuko Takashima, Eiji Kobayashi, Akiko Kato, Takahiro Marui, Hiroaki Sagawa, Tatsuji Enoki, Ikunoshin Kato
  • METHOD OF PRODUCING LYMPHOCYTES
    Publication number: 20100255578
    Abstract: A method of producing lymphocytes characterized by comprising the step of culturing lymphocytes in the presence of a modified recombinant fibronectin fragment which has overlapping parts of the heparin-binding domain of fibronectin. This method makes it possible to achieve a high cell proliferation rate. The lymphocytes obtained thereby are appropriately usable in, for example, adoptive immunotherapy and, therefore, expected as highly useful in the clinical field. Moreover, a novel modified recombinant fibronectin fragment is provided.
    Type: Application
    Filed: June 7, 2007
    Publication date: October 7, 2010
    Inventors: Nobuko Muraki, Mitsuko Ideno, Kinuko Nagamine, Fuyuko Takashima, Eiji Kobayashi, Akiko Kato, Takahiro Marui, Hiroaki Sagawa, Tatsuji Enoki, Ikunoshin Kato