Patents by Inventor Kishore Kumar Joshi

Kishore Kumar Joshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified yeast cell and improved process for production of clot-specific streptokinase
    Patent number: 11008370
    Abstract: Disclosed herein is an expression system for the production and secretion of biologically active clot-specific streptokinase (CSSK) protein in methylotrophic yeast. Yeast-expressed CSSK protein displays improved plasminogen activation and fibrin selectivity. Further disclosed are methylotrophic yeast transformed with at least one copy of functional cDNA sequence encoding CSSK adjunct with modified signal sequence which results in secretion of mature and correctly processed CSSK.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: May 18, 2021
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Girish Sahni, Kishore Kumar Joshi
  • A GENETICALLY MODIFIED YEAST CELL AND IMPROVED PROCESS FOR PRODUCTION OF CLOT-SPECIFIC STREPTOKINASE
    Publication number: 20180362596
    Abstract: Disclosed herein is an expression system for the production and secretion of biologically active clot-specific streptokinase (CSSK) protein in methylotrophic yeast. Yeast-expressed CSSK protein displays improved plasminogen activation and fibrin selectivity. Further disclosed are methylotrophic yeast transformed with at least one copy of functional cDNA sequence encoding CSSK adjunct with modified signal sequence which results in secretion of mature and correctly processed CSSK.
    Type: Application
    Filed: October 26, 2016
    Publication date: December 20, 2018
    Applicant: Council of Scientific & Industrial Research
    Inventors: Girish Sahni, Kishore Kumar Joshi