Patents by Inventor Kiyohiko Nishi

Kiyohiko Nishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of manufacturing succinic acid and ammonium succinate solutions
    Patent number: 8034975
    Abstract: The present invention provides a method of manufacturing a highly pure ammonium succinate solution including the steps of (A) producing calcium succinate trihydrate by crystallization fermentation of a microorganism; (B) converting calcium succinate trihydrate to calcium succinate monohydrate by transition crystallization; (C) separating the calcium succinate monohydrate crystals; (D) substituting the calcium salt in the calcium succinate monohydrate with ammonium salt resulting in an ammonium succinate solution; and (E) removing the solid calcium carbonate from the ammonium succinate solution.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: October 11, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kiyohiko Nishi, Hiroshi Kaneko, Hirofumi Tasaki, Masaki Koga, Tetsuo Tanegawa, Seisaku Furuya, Kenji Fujiwara, Takeru Sato
  • METHOD OF MANUFACTURING SUCCINIC ACID AND AMMONIUM SUCCINATE SOLUTIONS
    Publication number: 20100094051
    Abstract: The present invention provides a method of manufacturing a highly pure ammonium succinate solution including the steps of (A) producing calcium succinate trihydrate by crystallization fermentation of a microorganism; (B) converting calcium succinate trihydrate to calcium succinate monohydrate by transition crystallization; (C) separating the calcium succinate monohydrate crystals; (D) substituting the calcium salt in the calcium succinate monohydrate with ammonium salt resulting in an ammonium succinate solution; and (E) removing the solid calcium carbonate from the ammonium succinate solution.
    Type: Application
    Filed: November 18, 2009
    Publication date: April 15, 2010
    Inventors: Kiyohiko Nishi, Hiroshi Kaneko, Hirofumi Tasaki, Masaki Koga, Tetsuo Tanegawa, Seisaku Furuya, Kenji Fujiwara, Takeru Sato
  • Method for producing non-amino organic acid
    Patent number: 7563606
    Abstract: Non-amino organic acids such as succinic acid, malic acid and fumaric acid are produced by reacting bacterial cells or treated bacterial cells of a coryneform bacterium with an organic raw material in an aqueous medium containing magnesium carbonate and/or magnesium hydroxide, and a certain range of concentration of a monovalent cation, while maintaining the pH within a certain range without increasing the volume of the aqueous medium.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: July 21, 2009
    Assignees: Mitsubishi Chemical Corporation, Ajinomoto Co., Inc.
    Inventors: Ryusuke Aoyama, Makoto Murase, Kenji Yamagishi, Kiyohiko Nishi, Hiroyuki Kojima
  • Methods of producing prenyl alcohols
    Patent number: 7501268
    Abstract: A method of producing a prenyl alcohol, comprising creating a recombinant by transferring into a host a recombinant DNA for expression or a DNA for genomic integration each comprising a prenyl diphosphate synthase gene or a mutant thereof, culturing the resultant recombinant, and recovering the prenyl alcohol from the resultant culture.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: March 10, 2009
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Chikara Ohto, Shusei Obata, Masayoshi Muramatsu, Kiyohiko Nishi, Kazuhiko Totsuka
  • Method for producing cadaverine dicarboxylate
    Patent number: 7189543
    Abstract: Cadaverine dicarboxylate is produced by performing an enzymatic decarboxylation reaction of a lysine solution while adding a dicarboxylic acid containing 4 to 10 carbons to the lysine solution to maintain pH of the solution at a level sufficient for the enzymatic decarboxylation reaction to occur, for example, 4.0 to 8.0.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: March 13, 2007
    Assignee: Ajinomoto Co., Inc.
    Inventors: Kiyohiko Nishi, Shuichi Endo, Yukiko Mori, Kazuhiko Totsuka, Yoshinori Hirao
  • Method for producing non-amino organic acid
    Publication number: 20060281156
    Abstract: Non-amino organic acids such as succinic acid, malic acid and fumaric acid are produced by reacting bacterial cells or treated bacterial cells of a coryneform bacterium with an organic raw material in an aqueous medium containing magnesium carbonate and/or magnesium hydroxide, and a certain range of concentration of a monovalent cation, while maintaining the pH within a certain range without increasing the volume of the aqueous medium.
    Type: Application
    Filed: March 16, 2006
    Publication date: December 14, 2006
    Applicants: MITSUBISHI CHEMICAL CORPORATION, AJINOMOTO CO., INC.
    Inventors: Ryusuke Aoyama, Makoto Murase, Kenji Yamagishi, Kiyohiko Nishi, Hiroyuki Kojima
  • Method for producing cadaverine dicarboxylate
    Publication number: 20050003497
    Abstract: Cadaverine dicarboxylate is produced by performing an enzymatic decarboxylation reaction of a lysine solution while adding a dicarboxylic acid containing 4 to 10 carbons to the lysine solution to maintain pH of the solution at a level sufficient for the enzymatic decarboxylation reaction to occur, for example, 4.0 to 8.0.
    Type: Application
    Filed: May 24, 2004
    Publication date: January 6, 2005
    Inventors: Kiyohiko Nishi, Shuichi Endo, Yukiko Mori, Kazuhiko Totsuka, Yoshinori Hirao