Patents by Inventor Kiyoshi Murase
Kiyoshi Murase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4457872Abstract: A novel 2-hydroxyoxanilic acid derivative shown by the following formula ##STR1## or a salt thereof. This compound possesses an immunoregulatory action and is useful as an antiallergic agent, an antiasthmatic, an antirheumatic, a carcinostatic agent, a therapeutic agent for autoimmune disease, and a suppressant of rejection at the tissue transplantation and skin graft.Type: GrantFiled: September 9, 1982Date of Patent: July 3, 1984Assignee: Yamanouchi Pharmaceutical Co.Inventors: Kiyoshi Murase, Toshiyasu Mase, Hideki Arima, Kenichi Tomioka, Yoso Numasaki
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Patent number: 4414153Abstract: Substituted 1,3-dithietane-2-carboxylic acid derivatives useful as intermediates for the preparation of highly effective penicillin and cephalosporin derivatives and the preparation thereof.Type: GrantFiled: September 23, 1981Date of Patent: November 8, 1983Assignee: Yamanouchi Pharmaceutical Co. Ltd.Inventors: Masaru Iwanami, Tetsuya Maeda, Yoshinobu Nagano, Masaharu Fujimoto, Noriaki Nagano, Atsuki Yamazaki, Kazaharu Tamazawa, Kiyoshi Murase, Tadao Shibanuma
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Patent number: 4405480Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative proportions, 93.18-99.85 wt. % SrTiO.sub.3, 0.13-5.32 wt. % Nb.sub.2 O.sub.5, and 0.02-1.50 wt. % CuO. The secondary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.03-2.75 wt. % PbO, 0.12-4.23 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Kazuji Onigata
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Patent number: 4405477Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative proportions, 91.92-99.62 wt. % SrTiO.sub.3, 0.33-4.08 wt. % Ta.sub.2 O.sub.5, and 0.05-4.00 wt. % GeO.sub.2. The secondary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.02-2.83 wt. % PbO, 0.11-4.33 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1980Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Kazuji Onigata
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Patent number: 4405478Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative proportions, 90.68-99.88 wt. % SrTiO.sub.3, 0.07-5.32 wt. % Nb.sub.2 O.sub.5, and 0.05-4.00 wt. % GeO.sub.2. The secondary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.03-2.90 wt. % PbO, 0.11-4.34 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4405475Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative proportions, 91.18-99.82 wt. % SrTiO.sub.3, 0.13-5.32 wt. % Nb.sub.2 O.sub.5, and 0.05-3.50 wt. % ZnO. The secondary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.03-2.90 wt. % PbO, 0.11-4.28 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4405479Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative proportions, 95.20-99.80 wt. % SrTiO.sub.3, 0.15-2.30 wt. % WO.sub.3, and 0.05-2.50 wt. % ZnO. The seconary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.03-2.75 wt. % PbO, 0.11-4.23 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4405473Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative porportions, 94.50-99.62 wt. % SrTiO.sub.3, 0.33-3.00 wt. % Ta.sub.2 O.sub.5, and 0.05-2.50 wt. % ZnO. The secondary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.03-2.80 wt. % PbO, 0.11-4.38 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4405476Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increse in apparent relative dielectric constant. The primary ingredients comprise in relative proportions, 94.50-99.82 wt. % SrTiO.sub.3, 0.13-2.50 wt. % WO.sub.3 and 0.05-3.00 wt. % GeO.sub.2. The secondary ingredients comprise 0.02-0.10 wt. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.03-2.90 wt. % PbO, 0.10-4.28 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4405472Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise, in relative proportions, 95.18-99.65 wt. % SrTiO.sub.3, 0.33-3.32 wt. % Ta.sub.2 O.sub.5, and 0.02-1.50 wt. % CuO. The secondary ingredients comprise 0.02-0.10 wt. % part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.50 to 5.0. The insulating substances comprise 0.03-2.75 wt. % PbO, 0.11-4.22 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4405474Abstract: A dielectric ceramic material composed of primary and secondary ingredients forming in combination a polycrystalline ceramic proper, and of insulating substances diffused throughout the intergranular boundaries of the ceramic proper for an increase in apparent relative dielectric constant. The primary ingredients comprise in relative proportions, 96.70-99.83 wt. % SrTiO.sub.3, 0.15-2.30 wt. % WO.sub.3, and 0.02-1.00 wt. % CuO. The secondary ingredients comprise 0.02-0.10 wt %. part SiO.sub.2 and 0.01-0.03 wt. part Al.sub.2 O.sub.3 with respect to 100 wt. parts of the primary ingredients, with the weight ratio of SiO.sub.2 to Al.sub.2 O.sub.3 being from 1.5 to 5.0. The insulating substances comprise 0.003-2.83 wt. % PbO, 0.10-4.30 wt. % Bi.sub.2 O.sub.3, and 0.001-0.18 wt. % B.sub.2 O.sub.3 with respect to the total weight of the primary and the secondary ingredients.Type: GrantFiled: November 22, 1982Date of Patent: September 20, 1983Assignee: Taiyo Yuden Co., Ltd.Inventors: Kiyoshi Murase, Nobutatsu Yamaoka, Masayuki Fujimoto
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Patent number: 4198339Abstract: Substituted 1,3-dithietane-2-carboxylic acid derivatives useful as intermediates for the preparation of highly effective penicillin and cephalosporin derivatives and the preparation thereof.Type: GrantFiled: June 7, 1978Date of Patent: April 15, 1980Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masaru Iwanami, Tetsuya Maeda, Yoshinobu Nagano, Masaharu Fujimoto, Noriaki Nagano, Atsuki Yamazaki, Kazaharu Tamazawa, Kiyoshi Murase, Tadao Shibanuma
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Patent number: 4167597Abstract: A process for extending the life of an antifouling paint film which comprises applying onto an antifouling paint film a coating of a water-permeable graft polymer prepared by polymerizing one or more vinyl monomers in the presence of a hydrophilic polymer. The coating of the water-permeable graft polymer has an excellent water-resistance and a proper water-permeability by which an antifouling agent contained in the antifouling paint film can be leached into sea water and moreover the leaching rate can be controlled. As a result, the antifouling property of the paint film is exhibited for a long period of time.Type: GrantFiled: April 28, 1978Date of Patent: September 11, 1979Assignee: Toa Paint Company, Ltd.Inventors: Morio Yoshida, Ikuo Asato, Toru Semba, Kiyoshi Murase
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Patent number: 4145363Abstract: There are disclosed novel 4-substituted amino-.alpha.-aminomethylbenzyl alcohol derivatives represented by the formula: ##STR1## wherein X represents a halogen atom; Y represents a hydrogen atom or a halogen atom; R.sub.1 represents a lower alkyl group, a carbamoyl group, a mono- or di-lower alkyl-substituted carbamoyl group, a phenyl-substituted carbamoyl group, a lower alkoxycarbonyl group, a lower alkoxy-substituted lower alkoxycarbonyl group, a phenyl-substituted lower alkoxycarbonyl group, or a cycloalkyloxycarbonyl group; and R.sub.2 represents a lower alkyl group, a cycloalkyl group, or the group shown by the ##STR2## wherein R.sub.3 represents a hydrogen atom or a lower alkyl group and R.sub.4 represents a hydrogen atom, a hydroxy group, or a lower alkoxy group and the pharmaceutically acceptable nontoxic salts thereof.These compounds are antiasthmatic agents useful for the prophylaxis and treatment of asthma.Type: GrantFiled: June 27, 1977Date of Patent: March 20, 1979Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masuo Murakami, Kozo Takahashi, Kiyoshi Murase, Toshiyasu Mase, Hisashi Ida, Toichi Takenaka
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Patent number: 4127675Abstract: Novel indene derivatives represented by the general formula ##STR1## wherein R represents lower alkyl, phenylloweralkyl or lower cycloalkyl, and acid addition salts thereof useful as .beta.-receptor antagonists.Type: GrantFiled: October 21, 1976Date of Patent: November 28, 1978Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masuo Murakami, Kiyoshi Murase, Kunihiro Niigata, Shiro Tachikawa, Toichi Takenaka
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Patent number: 4063025Abstract: There are disclosed novel 4-substituted amino-.alpha.-aminomethylbenzyl alcohol derivatives represented by the formula: ##STR1## wherein X represents a halogen atom; Y represents a hydrogen atom or a halogen atom; R.sub.1 represents a lower alkyl group, a carbamoyl group, a mono- or di-lower alkyl-substituted carbamoyl group, a phenyl-substituted carbamoyl group, a lower alkoxycarbonyl group, a lower alkoxy-substituted lower alkoxycarbonyl group, a phenyl-substituted lower alkoxycarbonyl group, or a cycloalkyloxycarbonyl group; and R.sub.2 represents a lower alkyl group, a cycloalkyl group, or the group shown by the formula ##STR2## wherein R.sub.3 represents a hydrogen atom or a lower alkyl group and R.sub.4 represents a hydrogen atom, a hydroxy group, or a lower alkoxy group and the pharmaceutically acceptable nontoxic salts thereof.These compounds are antiasthmatic agents useful for the prophylaxis and treatment of asthma.Type: GrantFiled: January 23, 1976Date of Patent: December 13, 1977Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masuo Murakami, Kozo Takahashi, Kiyoshi Murase, Toshiyasu Mase, Hisashi Ida, Toichi Takenaka
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Patent number: 4045482Abstract: Novel indene derivatives represented by the general formula ##STR1## wherein R represents lower alkyl, phenylloweralkyl or lower cycloalkyl, and acid addition salts thereof useful as .beta.-receptor antagonists.Type: GrantFiled: April 14, 1975Date of Patent: August 30, 1977Assignee: Yamanouchi Pharmaceutical Co. Ltd.Inventors: Masuo Murakami, Kiyoshi Murase, Kunihiro Niigata, Shiro Tachikawa, Toichi Takenaka
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Patent number: 3994974Abstract: Novel .alpha.-aminomethylbenzyl alcohol derivatives, particularly .alpha.-aminoethyl-3-substituted amino-4-hydroxybenzyl alcohol derivatives. The compounds of this invention are useful as bronchodilating agents.Type: GrantFiled: May 7, 1974Date of Patent: November 30, 1976Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masuo Murakami, Kozo Takahashi, Toshiyasu Mase, Kiyoshi Murase, Hisashi Ida