Patents by Inventor Kiyoshi Takatsuki

Kiyoshi Takatsuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thrombocytopoiesis stimulating factor
    Patent number: 5856444
    Abstract: An object of the present invention is to provide a physiologically active substance having activity in acting on the megakaryocyte-platelet system, in promoting the differentiation and maturation of megakaryocytes, and in promoting the formation of platelets. The present invention relates to a thrombocytopoiesis stimulating factor, characterized in having the following amino acid sequence in its molecule, and to a medicinal composition for treating thrombocytopenia, characterized in containing thrombocytopoiesis stimulating factor as an active component: Xaa Gly Asn Asn Asp Glu Ser Asn Ile Ser Phe Lys Glu Lys Asp Ile (where Xaa indicates that the amino acid is unspecified). The physiologically active substance is useful as an active component or the like in therapeutics and preventives for thrombocytopenia and thrombocytopenic purpura associated with chemotherapy and marrow grafts, and for various other diseases which are prone to bleeding attributed to thrombocytopenia.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: January 5, 1999
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Makoto Kawakita, Hiromitsu Matsuzaki, Kiyoshi Takatsuki, Kazushi Shibuya, Masato Higuchi
  • HIV monoclonal antibody specific for the HTLV-III.sub.mn gp120 envelope glycoprotein
    Patent number: 5712373
    Abstract: A murine monoclonal antibody which specifically binds to a glycoprotein antigen having a molecular weight of about 12.times.10.sup.4 daltons (gp120) present in the envelope of human T-lymphotropic virus III.sub.MN (HTLV-III.sub.MN) and capable of neutralizing the HTLV-III.sub.MN as determined by in vitro inhibition of syncytium formation but does not bind to other HTLV-III strains, or antigen-binding fragments, which is useful for prophylaxis, treatment and diagnosis of AIDS.
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: January 27, 1998
    Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
    Inventors: Yasuyuki Eda, Kiyoshi Osatomi, Kouichi Shiosaki, Sachio Tokiyoshi, Shuzo Matsushita, Toshio Hattori, Kiyoshi Takatsuki
  • Agent for treating or preventing AIDS using human urine trypsin inhibitor
    Patent number: 5504065
    Abstract: Human urine trypsin inhibitor is provided as an agent for treating acquired immunodeficiency syndrome (AIDS), preventing the infection with AIDS or preventing the onset of AIDS after such infection. It can be administered intravenously for the treatment and externally for the prevention.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: April 2, 1996
    Assignee: JCR Pharmaceuticals Co., Ltd.
    Inventors: Toshio Hattori, Kiyoshi Takatsuki, Yoshikazu Yuki
  • Antiretroviral agent, method of use thereas, and method of preparation
    Patent number: 5098927
    Abstract: Pyrroline compounds of the formulae (I) and (II) are effective in the treatment of retroviral infection and lymphadenopathy.
    Type: Grant
    Filed: January 10, 1991
    Date of Patent: March 24, 1992
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Kiyoshi Takatsuki, Yohsuke Maeda, Toshio Hattori, Tsutomu Kaizu, Masanori Okamoto, Yoshiko Yokota, Katsuya Nakamura, Hiroshi Kayakiri