Patents by Inventor Kiyoshi Tone

Kiyoshi Tone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10551387
    Abstract: A cancer cell detection method that makes it possible to perform imaging of cells in a living state and a dual detection method for cancer cells in which the aforementioned method is combined with a pre-existing dyeing method for cytodiagnosis. The method uses living body-derived cells and includes: incubating living cells included in a sample taken from a person together with a fluorescently-labeled L-glucose derivative and detecting the fluorescently-labeled L-glucose derivative that is taken up into the cells; and detecting fluorescence emitted by the L-glucose derivative that is present within the cells while the cells are attached to a thin glass or plastic plate. Also provided is a dual detection method for cancer cells in which the cancer cell detection method that uses living body-derived cells is combined with a dyeing method using cells that are fixed using an alcohol or the like.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: February 4, 2020
    Assignee: HIROSAKI UNIVERSITY
    Inventors: Katsuya Yamada, Ayako Sasaki, Kouki Ono, Kiyoshi Tone
  • Publication number: 20170315129
    Abstract: The purpose of the present invention is to provide a novel cancer cell detection method that uses living body-derived cells and that can be used even in cytodiagnosis. In particular, the purpose of the present invention is to provide a novel cancer cell detection method that makes it possible to perform imaging of cells in a living state and a dual detection method for cancer cells in which the aforementioned method is combined with a pre-existing dyeing method for cytodiagnosis. Provided is a cancer cell detection method that uses living body-derived cells and that includes: incubating living cells included in a sample taken from a person together with a fluorescently-labeled L-glucose derivative and detecting the fluorescently-labeled L-glucose derivative that is taken up into the cells; and detecting fluorescence emitted by the L-glucose derivative that is present within the cells while the cells are attached to a thin glass or plastic plate.
    Type: Application
    Filed: September 24, 2015
    Publication date: November 2, 2017
    Applicant: Hirosaki University
    Inventors: Katsuya YAMADA, Ayako SASAKI, Kouki ONO, Kiyoshi TONE
  • Patent number: 5814841
    Abstract: A self scanning light-emitting array is disclosed. A coupled array of light-emitting elements is constituted so that a light-emitting element in a minimal conducting state influences the next light-emitting element so that its threshold level is changed. When each element is driven by a common clock pulse, the change in threshold level is shifted in the longitudinal direction, so that a minimal conducting state is transferred in a clock period of the clock pulse.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: September 29, 1998
    Assignee: Nippon Sheet Glass Co., Ltd.
    Inventors: Yukihisa Kusuda, Kiyoshi Tone, Ken Yamashita, Shuhei Tanaka
  • Patent number: 5451977
    Abstract: A self-scanning light-emitting element array is disclosed. A coupled array of light-emitting elements is constituted so that a light-emitting element which is turned on influences a light-emitting element to be turned on next so that its threshold level is changed. When each element is clock-driven by a common drive pulse, the change in threshold level is shifted in the array direction, so that a turn-on operation is transferred in a clock period of the drive pulse.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: September 19, 1995
    Assignee: Nippon Sheet Glass Co., Ltd.
    Inventors: Yukihisa Kusuda, Kiyoshi Tone, Ken Yamashita, Shuhei Tanaka
  • Patent number: 5177405
    Abstract: A self-scanning, light-emitting device comprises an array of cells or blocks each having a self-scanning transfer element and a light-emitting element. Turn-on state of the transfer element is transferred to the subsequent transfer element in synchronism with clock pulses. Each light-emitting element is connected to the corresponding transfer element so as to emit light upon supplying current under an ON state of the transfer element. The light-emitting array generates a light image in accordance with a light emission current.
    Type: Grant
    Filed: July 24, 1990
    Date of Patent: January 5, 1993
    Assignee: Nippon Sheet Glass Co., Ltd.
    Inventors: Yukihisa Kusuda, Kiyoshi Tone, Ken Yamashita, Shuhei Tanaka, Seiji Ohno, Yasunao Kuroda, Nobuyuki Komaba