Patents by Inventor Kjell Bertheussen

Kjell Bertheussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serum-free cell culture media
    Patent number: 6833271
    Abstract: Cell culture media containing a sterol such as cholesterol stabilized by surfactant rather than serum products or phospholspid micelles and containing soluble carboxylic acids as fatty acid precursors to satisfy lipid requirements are further enhanced by the presence of alcohols promoting cell growth.
    Type: Grant
    Filed: June 12, 2001
    Date of Patent: December 21, 2004
    Assignee: Medi-Cult A/S
    Inventor: Kjell Bertheussen
  • A METHOD FOR IN VITRO MATURATION OF HUMAN GAMETES
    Publication number: 20020115211
    Abstract: The present invention relates to a method for in vitro maturation of a human gamete by culturing an immature human gamete in a chemically defined cell culture medium. The human gamete can be a spermatocyte or an oocyte. The maturation end point is metaII. The advantage of the described medium is a synchronised cumulus-, cytoand nuclear maturation completed within a period of 20 to 30 hours. The medium should preferably contain ATA (Aurin Tri Carboxylicacid) as an anti-apototic agent. The medium should preferably not contain BSA, HSA or other directly serum derived products or substances.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 22, 2002
    Applicant: MEDI-CULT A/S
    Inventors: Svend LINDENBERG , Anne Lis MIKKELSEN , Steven Dale SMITH , Kjell BERTHEUSSEN
  • Serum-free cell culture media
    Publication number: 20020031825
    Abstract: Cell culture media containing a sterol such as cholesterol stabilized by surfactant rather than serum products or phospholspid micelles and containing soluble carboxylic acids as fatty acid precursors to satisfy lipid requirements are further enhanced by the presence of alcohols promoting cell growth.
    Type: Application
    Filed: June 12, 2001
    Publication date: March 14, 2002
    Inventor: Kjell Bertheussen
  • In vitro maturation of human oocytes in one day
    Publication number: 20010028878
    Abstract: The present invention relates to a method for in vitro maturation of a human oocyte by culturing an immature human oocyte in a cell culture medium for 10-30 hours. The maturation end point is metaphase II.
    Type: Application
    Filed: December 22, 2000
    Publication date: October 11, 2001
    Inventors: Svend Lindenberg, Anne Lis Mikkelsen, Steven Dale Smith, Kjell Bertheussen
  • Serum-free growth medium and use thereof
    Patent number: 5045467
    Abstract: Serum-free growth medium comprising an iron-chelate, aurin-tricarboxylic acid and optionally alkali-metal-EDTA and trace elements together with possible growth factors, wherein the iron-chelate may comprise a mixture of Fe-EDTA and citric acid. The growth medium may be used for quality testing of other growth media, optionally together with a hybridoma cell line from p.sub.3 U.sub.1 tumor cells and B-lymphocytes, which hybridoma also is disclosed.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: September 3, 1991
    Assignees: Medi-Cult A/S, A/S GEA Farmaceutisk Fabrik
    Inventor: Kjell Bertheussen