Patents by Inventor Klaus-Dieter Graske

Klaus-Dieter Graske has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chiral heptyne derivatives for the preparation of epothilones and processes for their preparation
    Patent number: 7326798
    Abstract: The invention relates to a new synthetic process for the production of key intermediates useful in the synthesis of epothilones or epothilone derivatives, to certain compounds used to produce these key intermediates and to a process to produce said compounds.
    Type: Grant
    Filed: April 21, 2005
    Date of Patent: February 5, 2008
    Assignee: Schering AG
    Inventors: Johannes Platzek, Orlin Petrov, Marc Willuhn, Klaus Dieter Graske, Werner Skuballa
  • Process for the production of dendritic trimesic acid triamides
    Patent number: 7199268
    Abstract: A new process for the production of dendritic trimesic acid triamides is described.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: April 3, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Klaus-Dieter Graske
  • Process for the production of dendritic trimesic acid triamides
    Publication number: 20050238615
    Abstract: A new process for the production of dendritic trimesic acid triamides is described.
    Type: Application
    Filed: December 16, 2004
    Publication date: October 27, 2005
    Inventors: Johannes Platzek, Klaus-Dieter Graske
  • Process for the production of perbenzylated 1-O-glycosides
    Patent number: 6908989
    Abstract: The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof in which sugar1 is a monosaccharide that is functionalized in 1-OH-position, R represents benzyl, n means 2, 3 or 4, X means —COO— or —NH— and L means a straight-chain, branched, saturated or unsaturated C1-C30 carbon chain, which optionally is interrupted or substituted by groups. The process according to the invention starts from economical starting materials, provides good yields and allows the production of perbenzylated saccharides with 1-O-functionalized side chains on an industrial scale.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: June 21, 2005
    Assignee: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa, Klaus-Dieter Graske
  • Process for the production of peracylated 1-0-glycosides
    Patent number: 6831164
    Abstract: The invention relates to a process for the production of peracylated 1-O-glycosides of general formula I or salts thereof in which sugar1 is a monosaccharide that is functionalized in 1-OH-position, R represents methyl, ethyl, propyl, isopropyl, tbutyl, phenyl, n means 2, 3 or 4, X means —COO— or —NH—and L means a straight-chain, branched, saturated or unsaturated C1-C30 carbon chain, which optionally is interrupted or substituted by groups. The process according to the invention starts from economical starting materials, provides good yields and allows the production of peracylated saccharides with 1-O-functionalized side chains on an enlarged scale.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: December 14, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Klaus-Dieter Graske, Ulrich Niedballa
  • Process for the production of peracylated 1-0-glycosides
    Publication number: 20030069402
    Abstract: The invention relates to a process for the production of peracylated 1-O-glycosides of general formula I or salts thereof 1
    Type: Application
    Filed: July 11, 2002
    Publication date: April 10, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Klaus-Dieter Graske, Ulrich Niedballa
  • Process for the production of perbenzylated 1-O-glycosides
    Publication number: 20030055242
    Abstract: The invention relates to a process for the production of perbenzylated 1-O-glycosides of general formula I or salts thereof 1
    Type: Application
    Filed: June 19, 2002
    Publication date: March 20, 2003
    Inventors: Johannes Platzek, Ulrich Niedballa, Klaus-Dieter Graske
  • Process for the production of cyclene
    Patent number: 6156890
    Abstract: A new single-pot process for the production of cyclene is described.
    Type: Grant
    Filed: December 1, 1999
    Date of Patent: December 5, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Karsten Hoyer, Klaus-Dieter Graske, Bernd Raduechel
  • Process for the production of metal-complex carboxylic acid amides
    Patent number: 6045776
    Abstract: The invention relates to a process for the production of metal-complex carboxylic acid amides, characterized in that a metal-complex carboxylic acid mixture that consists of the metal-complex carboxylic acid and at least one solubilizing substance in dimethyl sulfoxide (DMSO) is pretreated with a dehydrating reagent, optionally with the addition of a coupling adjuvant, and is then reacted with an amine of general formula IA(NH.sub.2).sub.n (I),in whichA stands for the radical of a natural or synthetic amine, andn stands for numbers 1 to 100.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: April 4, 2000
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Bernd Raduchel, Heribert Schmitt-Willich, Klaus-Dieter Graske