Abstract: Masking apparatus and methods of masking a medical article, such as stent, for selective application of a coating composition on the article are disclosed.

Abstract: A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are used, while simultaneously reducing damage to the inner surface of the stent due to the shielding effect of the polymeric mandrel.

Abstract: A stent for treating a bodily lumen with a flexible section in a high strain region is disclosed. A flexible section may be selectively positioned to reduce an amount of strain in the high strain region when subjected to the applied stress during use to inhibit or prevent fracturing in the high strain region.

Abstract: A method of fabricating an implantable medical device, such as a stent, from a plastically deformed tube or sheet is described herein. The implantable medical device may be an endoprosthesis such as a stent. The method may include elongating a tube longitudinally along a cylindrical axis of the tube. The method may further include forming a pattern that includes at least one strut on the elongated tube. A further embodiment may include stretching a sheet along an axis of stretching. The method may include forming a tube from the stretched sheet. The method may further include forming a pattern including at least one strut on the stretched sheet or the tube.

Abstract: The invention provides a method of manufacturing a stent, the method comprising: disposing a polymeric tube into a cylindrical mold, the cylindrical mold having a variable diameter along a portion of the inside surface of the mold; radially expanding the tube by blowing a gas or liquid into the cylindrical mold, the outside surface of the tube conforming to the variable diameter portion of the outside surface of the mold, causing the radially expanded tube to have a variable diameter along the conformed length of the tube; and fabricating a stent from the expanded tube.

Abstract: Methods and systems of fabricating a polymeric stent are disclosed herein.

Abstract: An implantable medical device is disclosed having a helical construct including a set of spiral coils for local in vivo application of a therapeutic substance in a biological lumen. The helical construct is configured to apply less than 0.75 Bar of pressure to the biological lumen wall. The helical construct can have at least two sets of spiral coils having opposing helical directions. The device can be used for the treatment of vascular disorders such as restenosis and vulnerable plaque.

Abstract: This invention relates to a method of extending the shelf-life of constructs, in particular bioabsorbable stents, comprising semi-crystalline polymers by increasing the crystallinity of the polymers.

Abstract: A system for pulsed synchronized laser cutting of stents and/or other medical products includes a numerical controller and a machine for moving a tube of material during cutting. A pulsed fiber laser is configured to cut the tube into, for example, a stent, the numerical controller being in communication with the machine and configured to send movement control information to the machine. The numerical controller may also receive movement speed information from the machine. The numerical controller is also in communication with the pulsed fiber laser and is configured to send pulse control information to the pulsed fiber laser. The numerical controller is configured to cause average laser power to decrease by decreasing frequency of laser pulses as stent cutting speed decreases, and to cause average laser power to increase by increasing frequency of laser pulses as stent cutting speed increases.

Abstract: Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.

Abstract: Embodiments of methods and systems for laser machining a substrate in the fabrication of an implantable medical device are disclosed.

Abstract: Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.

Abstract: Embodiments of methods of laser machining that include inducing formation of a plasma plume from a process gas through interaction of the gas with a laser beam are disclosed. The methods may include removing material from the substrate by interaction of the induced plasma plume with the substrate. The process gas may be optimized to achieve a desired machining effect.

Abstract: Embodiments of methods of laser machining that include inducing formation of a plasma plume from a process gas through interaction of the gas with a laser beam are disclosed. The methods may include removing material from the substrate by interaction of the induced plasma plume with the substrate.

Abstract: Methods for fabricating a stent using a femtosecond laser with an Ytterbium Tungstate active medium are disclosed. In some embodiments, a method includes forming a pattern in the substrate with the laser, the pattern including a plurality of structural elements.

Abstract: Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.

Abstract: This invention relates to a method of extending the shelf-life of constructs, in particular bioabsorbable stents, comprising semi-crystalline polymers by increasing the crystallinity of the polymers.

Abstract: A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are used, while simultaneously reducing damage to the inner surface of the stent due to the shielding effect of the polymeric mandrel.

Abstract: A stent for treating a bodily lumen with a flexible section in a high strain region is disclosed. A flexible section may be selectively positioned to reduce an amount of strain in the high strain region when subjected to the applied stress during use to inhibit or prevent fracturing in the high strain region.

Abstract: An implantable medical device is provided that degrades upon contact with body fluids so as to limit its residence time within the body. The device is formed of a porous corrodible metal to simultaneously provide high strength and an accelerated corrosion rate. The corrosion rate of a device formed of metal subject to self-dissolution or of a combination of metals subject to galvanic corrosion is accelerated by its porous structure. Coating the corrodible metallic device with a degradable polymer serves to delay the onset of corrosion of the underlying metallic structure.