Patents by Inventor Klaus O. Minck

Klaus O. Minck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoacid derivatives inhibiting renin
    Patent number: 5215967
    Abstract: New amino acid derivatives of the formulaR.sup.1 --Z--NR.sup.2 --CHR.sup.3 --CR.sup.4 --(CHR.sup.5).sub.a --CO--E--Q--Ywherein R.sup.1 to R.sup.5, a, Z, E, Q and Y have the meanings defined herein, and salts thereof inhibit the activity of human plasma renin.
    Type: Grant
    Filed: November 30, 1989
    Date of Patent: June 1, 1993
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Joachim Gante, Peter Raddatz, Johannes Sombroek, Claus J. Schmitges, Klaus O. Minck
  • Peptides possessing renin inhibitory activity
    Patent number: 4812555
    Abstract: New peptides of the formula IX--Z--NR.sup.2 --CHR.sup.3 --CHOH--(CHR.sup.4).sub.n --CO--Ewherein X, Z, R.sup.2, R.sup.3, R.sup.4, E and n are as defined herein and their salts inhibit the activity of human plasma renin.
    Type: Grant
    Filed: March 22, 1988
    Date of Patent: March 14, 1989
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Peter Raddatz, Gunter Holzemann, Alfred Jonczyk, Claus J. Schmitges, Klaus O. Minck
  • Amino acid derivatives
    Patent number: 4721776
    Abstract: New amino acid derivatives of the formula IX--Z--NR.sup.2 --CHR.sup.3 --CHR.sup.4 --(CHR.sup.5).sub.n CO--B--D Iin which X, Z, R.sup.2, R.sup.3, R.sup.4, R.sup.5, B, D and n have the meanings defined herein, and their salts inhibit the activity of human plasma renin.
    Type: Grant
    Filed: November 14, 1986
    Date of Patent: January 26, 1988
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Peter Raddatz, Gunter Holzemann, Claus J. Schmitges, Klaus O. Minck
  • 1-Aryloxy-3-nitratoalkylamino-2-propanols and use as .beta.-receptor blocker
    Patent number: 4288452
    Abstract: Compounds of the formulaAr--O--CH.sub.2 --CHOH--CH.sub.2 --NH--RwhereinAr is phenyl; phenyl monosubstituted or polysubstituted by halogen, cyano, acylamino (in which the acyl group has 1-7 carbon atoms), alkanoyl of 1-4 carbon atoms, alkyl (in which the chain can be interrupted by 1 or 2 oxygen atoms or by one sulfur atom and/or in which a multiple bond can be present) of a total of 1-10 carbon atoms, cycloalkyl of 3-8 carbon atoms, and/or cycloalkoxy of 3-8 carbon atoms; naphthyl; indanyl; indenyl; tetralyl; indolyl; indolyl monosubstituted or polysubstituted by alkyl, each of 1-4 carbon atoms; carbazolyl; or 1,2,3,4-tetrahydro-2-oxoquinolyl; andR is nitratoalkyl of 2-10 carbon atoms,and the physiologically acceptable acid addition salts thereof have valuable pharmacological properties, e.g., which make them useful for prophylaxis and treatment of heart problems, e.g., as .beta.-receptor blockers.
    Type: Grant
    Filed: February 9, 1979
    Date of Patent: September 8, 1981
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Johannes Sombroek, Karl-Heinz Becker, Klaus O. Minck, Hans-Joachim Enenkel