Patents by Inventor Knappik Achim

Knappik Achim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein (poly)peptides libraries
    Publication number: 20060003334
    Abstract: The present invention relates to synthetic DNA sequences which encode one or more collections of homologous proteins/(poly)peptides, and methods for generating and applying libraries of these DNA sequences. In particular, the invention relates to the preparation of a library of human-derived antibody genes by the use of synthetic consensus sequences which cover the structural repertoire of antibodies encoded in the human genome. Furthermore, the invention relates to the use of a single consensus antibody gene as a universal framework for highly diverse antibody libraries.
    Type: Application
    Filed: April 29, 2004
    Publication date: January 5, 2006
    Applicant: Morphosys AG
    Inventors: Knappik Achim, Peter Pack, Ge Liming, Moroney Simon, Pluckthun Andreas
  • Protein/(poly)peptide libraries
    Patent number: 6828422
    Abstract: The present invention relates to synthetic DNA sequences which encode one or more collections of homologous proteins/(poly)peptides, and methods for generating and applying libraries of these DNA sequences. In particular, the invention relates to the preparation of a library of human-derived antibody genes by the use of synthetic consensus sequences which cover the structural repertoire of antibodies encoded in the human genome. Furthermore, the invention relates to the use of a single consensus antibody gene as a universal framework for highly diverse antibody libraries.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: December 7, 2004
    Assignee: Morphosys AG
    Inventors: Knappik Achim, Peter Pack, Ge Liming, Moroney Simon, Plückthun Andreas