Patents by Inventor Kohichi Fujita

Kohichi Fujita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compounds
    Patent number: 7902179
    Abstract: A pharmaceutical composition containing a heterocyclic compound of the formula (I) wherein each symbol is as defined in the specification, an isomer thereof, a solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient has a superior TNF-? production suppressing action. Accordingly, it is useful for the prophylaxis or treatment of various diseases caused by abnormal production of TNF-?.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: March 8, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yasuhiro Tanaka, Kohichi Fujita, Yoshitomo Chujoh, Syunsuke Fukuda, Yuka Ikenoue, Tomoyuki Tagami, Akira Chiba, Ariko Kodaira, Hideki Matsumoto, Tadakiyo Nakagawa, Tatsuhiro Yamada, Manabu Suzuki, Masahiro Murata
  • Benzene derivatives and pharmaceutical use thereof
    Patent number: 7459585
    Abstract: The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory cell adhesion molecule expression inhibitor, anti-inflammatory agent, antirheumatic agent, immunosuppressant, cancer metastasis inhibitor, remedy for arteriosclerosis and antiviral agent which contain the benzene derivative of the following general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: December 2, 2008
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Tsuji, Ariko Kodaira, Kenji Takehana, Tsuyoshi Kobayashi, Takashi Yamamoto
  • Heterocyclic compounds
    Patent number: 7279484
    Abstract: The inventive subject matter relates to compounds, pharmaceutical compositions, and kits containing a heterocyclic compound represented by the formula (I) wherein R is an alkyl group optionally having substituent(s) etc., X is an amino group optionally having substituent(s), Y1 and Y2 are nitrogen atoms etc., an isomer or solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: October 9, 2007
    Assignee: Ajinomoto Co., Inc.
    Inventors: Tatsuhiro Yamada, Tadakiyo Nakagawa, Yasuhiro Tanaka, Kohichi Fujita, Tomoyuki Tagami, Yuka Ikenoue, Shunsuke Fukuda, Yoshitomo Chujo, Manabu Suzuki, Masahiro Murata
  • Heterocyclic compounds
    Publication number: 20050250796
    Abstract: The inventive subject matter relates to compounds, pharmaceutical compositions, and kits containing a heterocyclic compound represented by the formula (I) wherein R is an alkyl group optionally having substituent(s) etc., X is an amino group optionally having substituent(s), Y1 and Y2 are nitrogen atoms etc., an isomer or solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: April 28, 2005
    Publication date: November 10, 2005
    Inventors: Tatsuhiro Yamada, Tadakiyo Nakagawa, Yasuhiro Tanaka, Kohichi Fujita, Tomoyuki Tagami, Yuka Ikenoue, Shunsuke Fukuda, Yoshitomo Chujo, Manabu Suzuki, Masahiro Murata
  • Benzene derivatives and pharmaceutical use thereof
    Publication number: 20050165114
    Abstract: The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory cell adhesion molecule expression inhibitor, anti-inflammatory agent, antirheumatic agent, immunosuppressant, cancer metastasis inhibitor, remedy for arteriosclerosis and antiviral agent which contain the benzene derivative of the following general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: March 24, 2005
    Publication date: July 28, 2005
    Applicant: AJINOMOTO CO. INC
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Tsuji, Ariko Kodaira, Kenji Takehana, Tsuyoshi Kobayashi, Takashi Yamamoto
  • Heterocyclic compounds
    Publication number: 20040147546
    Abstract: A pharmaceutical composition containing a heterocyclic compound of the formula (I) 1
    Type: Application
    Filed: February 24, 2004
    Publication date: July 29, 2004
    Inventors: Yasuhiro Tanaka, Kohichi Fujita, Yoshitomo Chujoh, Syunsuke Fukuda, Yuka Ikenoue, Tomoyuki Tagami, Akira Chiba, Ariko Kodaira, Hideki Matsumoto, Tadakiyo Nakagawa, Tatsuhiro Yamada, Manabu Suzuki, Masahiro Murata
  • Amidinophenylpyruvic acid derivatives
    Patent number: 6710056
    Abstract: An amidinophenylpyruvic acid derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an excellent antagonistic effect against activated blood coagulation factor VII.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: March 23, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Masayuki Sugiki, Kazuyuki Sagi, Kohichi Fujita, Takashi Kayahara, Shunji Takehana, Kuniya Sakurai, Kazumi Tashiro
  • Benzene derivatives and pharmaceutical use thereof
    Patent number: 6703379
    Abstract: The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory cell adhesion molecule expression inhibitor, anti-inflammatory agent, antirheumatic agent, immunosuppressant, cancer metastasis inhibitor, remedy for arteriosclerosis and antiviral agent which contain the benzene derivative of the following general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: March 9, 2004
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Tsuji, Ariko Kodaira, Kenji Takehana, Tsuyoshi Kobayashi, Takashi Yamamoto
  • Benzene derivatives and pharmaceutical use thereof
    Publication number: 20030166693
    Abstract: The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory cell adhesion molecule expression inhibitor, anti-inflammatory agent, antirheumatic agent, immunosuppressant, cancer metastasis inhibitor, remedy for arteriosclerosis and antiviral agent which contain the benzene derivative of the following general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: March 14, 2003
    Publication date: September 4, 2003
    Applicant: AJINOMOTO CO., INC
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Tsuji, Ariko Kodaira, Kenji Takehana, Tsuyoshi Kobayashi, Takashi Yamamoto
  • Amidinophenylpyruvic acid derivatives
    Publication number: 20030109547
    Abstract: An amidinophenylpyruvic acid derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an excellent antagonistic effect against activated blood coagulation factor VII.
    Type: Application
    Filed: June 5, 2002
    Publication date: June 12, 2003
    Applicant: AJINOMOTO CO. INC
    Inventors: Masayuki Sugiki, Kazuyuki Sagi, Kohichi Fujita, Takashi Kayahara, Shunji Takehana, Kuniya Sakurai, Kazumi Tashiro
  • Biscyclopropanecarboxamide compounds and pharmaceutical use thereof
    Patent number: 6563002
    Abstract: The present invention discloses biscyclopropanecarboxamide compounds and pharmaceutically acceptable salts thereof; and also NF-kappa B activation inhibitors, Inflammatory cytokine production inhibitors, matrix metalloprotease production inhibitors, inflammatory cell adhesion molecules incidence inhibitors, antiinflammatory agents, antirheumatic agents, immunosuppressive agents, cancerous metastasis inhibitors or antiviral agents each containing such a compound as the active ingredient.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: May 13, 2003
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Yamamoto, Kenji Takehana, Tsuyoshi Kobayashi
  • Biscyclopropanecarboxamide compounds and pharmaceutical use thereof
    Publication number: 20020161053
    Abstract: The present invention discloses biscyclopropanecarboxamide compounds and pharmaceutically acceptable salts thereof; and also NF-kappa B activation inhibitors, Inflammatory cytokine production inhibitors, matrix metalloprotease production inhibitors, inflammatory cell adhesion molecules incidence inhibitors, antiinflammatory agents, antirheumatic agents, immunosuppressive agents, cancerous metastasis inhibitors or antiviral agents each containing such a compound as the active ingredient.
    Type: Application
    Filed: March 1, 2002
    Publication date: October 31, 2002
    Applicant: AJINOMOTO CO. INC.
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Yamamoto, Kenji Takehana, Tsuyoshi Kobayashi
  • Benzene derivatives and Pharmaceutical use thereof
    Publication number: 20010018441
    Abstract: The present invention provides an AP-1 activation inhibitor, NF-kappa B activation inhibitor, inflammatory cytokine production inhibitor, matrix metalloprotease production inhibitor, inflammatory cell adhesion molecule expression inhibitor, anti-inflammatory agent, antirheumatic agent, immunosuppressant, cancer metastasis inhibitor, remedy for arteriosclerosis and antiviral agent which contain the benzene derivative of the following general formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: March 12, 2001
    Publication date: August 30, 2001
    Applicant: Ajinomoto Co., Inc.
    Inventors: Yukio Iino, Kohichi Fujita, Takashi Tsuji, Ariko Kodaira, Kenji Takehana, Tsuyoshi Kobayashi, Takashi Yamamoto