Abstract: A bispecific antibody including a first domain which specifically binds to a mutant calreticulin protein and a second domain which specifically binds to a CD3 antigen. A pharmaceutical composition including the bispecific antibody or a functional fragment thereof. A diagnostic method for a myeloproliferative neoplasm, including detecting a polypeptide in a biological sample with the bispecific antibody.

Abstract: An editing support apparatus for supporting editing of an electric circuit, includes a first converter configured to convert an operation on a contact type input device into a first command, a second converter configured to convert a voice signal into a second command, and an editing unit configured to update the electric circuit in accordance with the first command and the second command. The editing unit updates a conductive path that forms a part of the electric circuit in accordance with the second command provided from the second converter when editing the conductive path.

Abstract: A method for measuring a resistivity of a silicon single crystal by a four-point probe method including: a first grinding step of grinding at a surface of the silicon single crystal on which the resistivity is measured; a cleaning step of cleaning the silicon single crystal subjected to the first grinding step; a donor-annihilation heat treatment step of heat-treating the silicon single crystal subjected to the cleaning step; and a second grinding step of grinding at least the surface of the silicon single crystal subjected to the donor-annihilation heat treatment step on which the resistivity is to be measured, where the resistivity of the silicon single crystal is measured by the four-point probe method after performing the second grinding step. This provides a method for measuring a resistivity of a silicon single crystal by which stable measurement is possible over a long period of time after a donor-annihilation heat treatment.

Abstract: A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance P, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.

Abstract: A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance P, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.

Abstract: A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance P, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.

Abstract: A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance P, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.

Abstract: A needle roller bearing retainer of the invention for supporting the planetary gear of a planetary gear mechanism rotatably includes an annular part and multiple pillar parts extending in the axial direction from the annular part, holds a roller between the adjoining pillar parts, and is used in an outer ring guide system, while a composite film containing phosphate and solid lubricant selected from soft metal-based solid lubricant and layer crystal structure material, or, a composite film containing phosphate and phosphorous compound having soft metal is formed at least on the outer peripheral surface of the retainer.

Abstract: A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance P, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.

Abstract: A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme of substance P, is administered locally in a dosage not influencing blood pressure, and a pharmaceutical for improving dysphagia containing the composition.

Abstract: Provided is a spacer for a radial needle roller bearing that keeps dynamic torque of a double-row radial needle roller bearing low, while suppressing wear in areas of rubbing with adjacent members by causing there to be a film of oil having a proper amount of oil to exist in the areas of rubbing without excessive surface area. Concave sections that are recessed in a direction away from the adjacent members of the column sections 13a or rim sections 12 are formed in the outside surfaces in the radial direction and/or circumferential direction of the column sections 13a, and/or in the outside surfaces in the radial and/or axial direction of the rim sections 12, and preferably radial concave sections 22 having bottom and that are recessed toward the inside in the radial direction are formed in the outside surfaces in the radial direction of the column sections 13a.

Abstract: By efficiently lowering a water temperature of a sea surface to thereby suppress an evaporation of a water vapor from the sea surface by lowering the water temperature of the sea surface, a generation of an atmospheric depression is prevented or its strength is weakened. Further, by suppressing a rise of the sea surface temperature, a generation of a red tide or a blue tide is prevented or reduced.

Abstract: The system and method accepts the inputs of an aggregate (long-range) production plan draft, a profit and loss target, a sales target, and a stock target. Then, the accepted long-range production plan draft is deployed into master production schedule and then a feasibility of the long-range production schedule draft is simulated. Based on the simulated result, the system and method calculates an amended schedule, a predicted profit and loss, and predicted sales of the long-range production schedule draft. Further, a supply schedule is calculated on the middle-range production schedule draft deployed from the long-range plan draft. Based on the supply schedule, the middle-range production schedule draft, and a planned buying unit price, the system and method calculates a predicted stock, an estimated loss of inventory price decline, and a planned acquisition cost of inventory. Each calculated prediction data item is displayed on screen.

Abstract: An autonomous and decentralized production control system comprising a plurality of production cells for performing the assembly and machining work. Each production cell proceeds with the production procedure by performing jobs in accordance with the works charged thereinto. A first embodiment comprises working cells each including a device for determining the working cell for executing an intended job. A second embodiment comprises a pallet for carrying an object of a job, and a device for determining the order of job priority in order to meet the product delivery time. Each working cell decides on the advisability and time of performing the job on the object, thereby autonomously implementing the production control.

Abstract: By efficiently lowering a water temperature of a sea surface to thereby suppress an evaporation of a water vapor from the sea surface by lowering the water temperature of the sea surface, a generation of an atmospheric depression is prevented or its strength is weakened. Further, by suppressing a rise of the sea surface temperature, a generation of a red tide or a blue tide is prevented or reduced.

Abstract: The present invention provides a master production scheduling system in which overstocked parts are disposed of with minimum loss.

Abstract: The system and method accepts the inputs of an aggregate (long-range) production plan draft, a profit and loss target, a sales target, and a stock target. Then, the accepted long-range production plan draft is deployed into master production schedule and then a feasibility of the long-range production schedule draft is simulated. Based on the simulated result, the system and method calculates an amended schedule, a predicted profit and loss, and predicted sales of the long-range production schedule draft. Further, a supply schedule is calculated on the middle-range production schedule draft deployed from the long-range plan draft. Based on the supply schedule, the middle-range production schedule draft, and a planned buying unit price, the system and method calculates a predicted stock, an estimated loss of inventory price decline, and a planned acquisition cost of inventory. Each calculated prediction data item is displayed on screen.

Abstract: A FIFO memory device for use in data transfer between data processing apparatuses having different data bus widths, has an input circuit 11 with a data bus width of k bits, an output circuit 12 with a data bus width of N×k bits (where N>1) that outputs data within the FIFO memory device, a writing pointer 2 that points to a data writing address of the FIFO memory device, a reading pointer 4 that points to a data reading address of the FIFO memory device, and a valid/invalid indicating circuit 6 that indicates whether or not data output to the output circuit 12 is valid.

Abstract: A position information acquiring apparatus for receiving an electric wave and for on the basis of the received signal, acquiring the position information exhibiting the position where the product is kept to record successively the position information thus acquired is packed together with an objective matter of conveyance in a package box and then is operated in the state of being able to be moved to receive an electric wave signal radiated from the GPS satellite group to acquire successively the position information. On the basis of the position information, a map of a part corresponding to the position information is retrieved from map information which is previously obtained to carry out an output for showing visibly the resultant partial map and a symbol with which the position contained in a position history information is shown on the map.

Abstract: A product configuration is managed on a product basis for each of component parts included in products from manufacturing to disposal of the products. A product manufacturer device, part manufacturer devices, and a device of a customer who possesses a product are interconnected through a communication line. The product manufacturer device includes configuration information on each of component parts in the product on a product number basis, and provides information and services on the product. The part manufacturer device includes configuration information on each of lower parts which include the component parts on a manufacturing lot or product number basis, and provides information and services on each of the parts. When the product configuration is changed, such change is reflected to the configuration information of the product and the component parts.