Patents by Inventor Koichiro Tobe

Koichiro Tobe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6596696
    Abstract: Maltoligosaccharide derivatives represented by the general formula: wherein n is an integer of 0 to 3 and X is a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts, and an &agr;-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia such as diabetes containing them as an active ingredient.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 22, 2003
    Assignee: Kikkoman Corporation
    Inventors: Riichiro Uchida, Ayako Nasu, Yukihiko Iwai, Takao Someya, Koichiro Tobe
  • Patent number: 6444239
    Abstract: An isoflavone aglycone-containing composition having genistein as a main aglycone is produced by a process comprising allowing a protease and &bgr;-glucosidase to act on a soy protein raw material, an extract of a soy protein raw material or a by-product of a soy protein raw material to water-solubilize the protein of soybean origin and to convert isoflavone glycosides to the corresponding aglycones, separating water-soluble components from the enzymatic reaction mixture, and recovering water-insoluble matter.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: September 3, 2002
    Assignee: Kikkoman Corporation
    Inventors: Akio Obata, Tatuo Manaka, Koichiro Tobe, Toru Izumi, Makoto Saito, Mamoru Kikuchi
  • Publication number: 20010010930
    Abstract: An isoflavone aglycone-containing composition having genistein as a main aglycone is produced by a process comprising allowing a protease and &bgr;-glucosidase to act on a soy protein raw material, an extract of a soy protein raw material or a by-product of a soy protein raw material to water-solubilize the protein of soybean origin and to convert isoflavone glycosides to the corresponding aglycones, separating water-soluble components from the enzymatic reaction mixture, and recovering water-insoluble matter.
    Type: Application
    Filed: January 25, 2001
    Publication date: August 2, 2001
    Applicant: Kikkoman Corporation
    Inventors: Akio Obata, Tatuo Manaka, Koichiro Tobe, Toru Izumi, Makoto Saito, Mamoru Kikuchi
  • Patent number: 6264997
    Abstract: A proanthocyanidin and an isoflavone are incorporated into a food. Compounding of grape seed extract as a proanthocyanidin and soy sauce cake extract as an isoflavone gives an anti-arteriosclerotic composition that is effective at a small intake.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: July 24, 2001
    Assignee: Kikkoman Corporation
    Inventors: Jun Yamakoshi, Makoto Saito, Akio Obata, Toru Izumi, Koichiro Tobe
  • Patent number: 6060597
    Abstract: A cyclic oligosaccharide or salts thereof comprising glucoses bound cyclically via .alpha.-1,6-linkages and having at least one S-oxo acid group bound, and ana gent for preventing or treating retroviral diseases which comprises said cyclic oligosaccharide or salts thereof as an active ingredient. The novel sulfated cyclic isomaltoligosaccharide inhibits infection of host cells with various retroviruses such as AIDS virus etc. so effectively that it has a significant preventive and therapeutic effect on diseases caused by retroviruses. Accordingly, said oligosaccharide can be utilized as an agent for preventing or treating retroviral diseases in pharmaceutical industry.
    Type: Grant
    Filed: July 30, 1998
    Date of Patent: May 9, 2000
    Assignees: Kikkoman Corporation, Noda Institute for Scientific Research
    Inventors: Koichiro Tobe, Makoto Saito, Shoichi Tokutake, Satoshi Kitao, Tetsuya Oguma, Kahee Fujita
  • Patent number: 6051234
    Abstract: A health diet for preventing life-habit diseases (adult diseases) is provided.The health diet is prepared by directly encapsulating or tableting an organic solvent extract of soy sauce cakes or an aqueous alkali extract of a soy sauce oil, or blending the extracts with a diet.
    Type: Grant
    Filed: February 4, 1998
    Date of Patent: April 18, 2000
    Assignee: Kikkoman Corporation
    Inventors: Shigehiro Kataoka, Akio Obata, Jun Yamakoshi, Yukihiko Iwai, Tatuo Manaka, Toru Izumi, Koichiro Tobe, Nobuyuki Yamaji
  • Patent number: 5453369
    Abstract: The present invention relates to a novel cycloisomaltooligosaccharide selected from the group consisting of novel cycloisomaltoheptaose having a cyclic structure composed of 7 glucose residues in .alpha.-1,6 linkage, novel cycloisomaltooctaose having a cyclic structure composed of 8 glucose residues in .alpha.-1,6 linkage and novel cycloisomaltononaose having a cyclic structure composed of 9 glucose residues in .alpha.-1,6 linkage, novel cycloisomaltooligosaccharide synthase forming said oligosaccharides from dextran, and a process for producing said oligosaccharides by use of said enzyme or a microorganism capable of producing said enzyme.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: September 26, 1995
    Assignees: Kikkoman Corporation, Noda Institute for Scientific Research
    Inventors: Tetsuya Oguma, Tatsuo Horiuchi, Koichiro Tobe
  • Patent number: 5364936
    Abstract: The present invention relates to a novel cycloisomaltooligosaccharide selected from the group consisting of novel cycloisomaltoheptaose having a cyclic structure composed of 7 glucose residues in .alpha.-1,6 linkage, novel cycloisomaltooctaose having a cyclic structure composed of 8 glucose residues in .alpha.-1,6 linkage and novel cycloisomaltononaose having a cyclic structure composed of 9 glucose residues in .alpha.-1,6 linkage, novel cycloisomaltooligosaccharide synthase forming said oligosaccharides from dextran, and a process for producing said oligosaccharides by use of said enzyme or a microorganism capable of producing said enzyme.
    Type: Grant
    Filed: December 28, 1993
    Date of Patent: November 15, 1994
    Assignees: Kikkoman Corporation, Noda Institute for Scientific Research
    Inventors: Tetsuya Oguma, Tatsuo Horiuchi, Koichiro Tobe