Abstract: A method for forming an embedded mirror structure is disclosed. The method includes preparing a structure that has a substrate and a waveguide layer on the substrate. The waveguide layer includes a core. Also, the waveguide has a top surface and a cavity side surface that defines a cavity opened at the top surface and aligned to the core. The method further includes coating metal particles on the cavity side surface inside the cavity of the waveguide layer to form a metal particle film on the cavity side surface.

Abstract: An optical device includes: a substrate including plural waveguide cores; and an optical component provided on the substrate, the optical component including plural lenses, each of the plural lenses transmitting light passing through one of the corresponding plural waveguide cores on the substrate. The substrate and the optical component are each provided with a positioning structure. The positioning structure includes plural protrusions and plural recesses provided on the substrate and the optical component. Each of the plural recesses accommodates a corresponding one of the plural protrusions, and an outer surface of each of the plural protrusions contacts a positioning surface of a corresponding one of the plural recesses. The positioning surface is a part of an inner surface of each of the plural recesses having accommodated the corresponding one of the plural protrusions to position the plural lenses relative to the substrate.

Abstract: The reservoir tank includes a reservoir body which reserves a fluid in an inner portion thereof formed to be in a hollow box shape. The reservoir body includes a port extending outward, a reservoir chamber which reserves the fluid and a port chamber which volume is smaller than that of the reservoir chamber and is in fluid communication with the port and a first communication passage positioned at a portion lower than a changeable liquid surface of the fluid reserved in the reservoir chamber in a vertical direction and provided at the first partition portion to allow the fluid communication between the reservoir chamber and the port chamber and wherein the port chamber and the port are kept being a state in which they are filled with the fluid supplied from the reservoir chamber via the first communication passage.

Abstract: A range-finding device including a light-emitting device, an imaging unit, a calculator, and a controller. The image unit receives pulsed light reflected from an object within the space for a plurality of time periods in a time-division manner, electrically converts the pulsed light into an electrical signal, and accumulates electric charge of the electrical signal for each of the plurality of time periods. The calculator calculates a time difference between emission of the pulsed light and reception of the pulsed light reflected from the object based on the electric charge accumulated for each of the plurality of time periods and determine a distance to the object based on the time difference. The controller controls the timing of reception of the pulsed light for each of the plurality of time periods at the imaging unit according to an intensity of the pulsed light reflected from the object.

Abstract: An optical device includes a substrate including plural waveguide cores and an optical component provided on the substrate. The plural waveguide cores allowing light to pass through the plural waveguide cores and the optical component including plural lenses Each of the plural lenses transmitting light passing through a corresponding one of the plural waveguide cores on the substrate, wherein the optical component includes a body and a protrusion The body being provided with the plural lenses, the protrusion being protruded from a side of the body, and the protrusion is fixed to the substrate with an adhesive.

Abstract: An optical device includes: a substrate including plural waveguide cores; and an optical component provided on the substrate, the optical component including plural lenses, each of the plural lenses transmitting light passing through one of the corresponding plural waveguide cores on the substrate. The substrate and the optical component are each provided with a positioning structure. The positioning structure includes plural protrusions and plural recesses provided on the substrate and the optical component. Each of the plural recesses accommodates a corresponding one of the plural protrusions, and an outer surface of each of the plural protrusions contacts a positioning surface of a corresponding one of the plural recesses. The positioning surface is a part of an inner surface of each of the plural recesses having accommodated the corresponding one of the plural protrusions to position the plural lenses relative to the substrate.

Abstract: An optical structure includes a substrate including a cavity on a first surface of the substrate, an optical component on the substrate and an adhesive applied to a side of the optical component to fix the optical component to the substrate. The optical component includes a recess on a second surface of the optical component, the second surface is opposed to the first surface of the substrate, and the recess is provided along an edge of the second surface.

Abstract: A distance measurement device includes a projection optical system, a light-receiving system to receive light projected from projection optical system and reflected by an object; and a correction system to correct a difference in timing of light emission between the plurality of light sources. The projection optical system includes a plurality of light sources and a plurality of drive circuits to drive the plurality of light sources.

Abstract: Provided are a novel compound having an antagonistic activity for the P2X7 receptor, and a pharmaceutical composition having an antagonistic activity for the P2X7 receptor. The compound represented by Formula (I): wherein the symbols are defined in the specification, or a pharmaceutically acceptable salt thereof.

Abstract: A distance measurement device includes a projection optical system, a light-receiving system to receive light projected from projection optical system and reflected by an object; and a correction system to correct a difference in timing of light emission between the plurality of light sources. The projection optical system includes a plurality of light sources and a plurality of drive circuits to drive the plurality of light sources.

Abstract: An optical structure is presented. The optical structure includes a substrate including a cavity on a first surface of the substrate. The optical structure further includes an optical component on the substrate, the optical component including a second surface opposed to the first surface of the substrate. The optical structure also includes an adhesive in a gap between the first surface of the substrate and the second surface of the optical component affixing the optical component to the substrate, wherein at least one of the first surface of the substrate and the second surface of the optical component includes a predetermined portion arranged around the cavity, wherein the predetermined portion prevents the adhesive from infiltrating.

Abstract: A range finding apparatus includes a light emission unit including a light source and a light source driver, a light detection unit, and circuitry. The light source driver supplies a plurality of drive pulses having different pulse width at different time periods. The light detection unit receives the light emitted from the light emission unit and then reflected from an object. The circuitry calculates a range to the object based on a time difference between one time point when a pulse light is emitted from the light source and another time point when light reflected from the object is received by the light detection unit. One of the drive pulses set with a smaller pulse width is set with a sine wave pattern, and another one of the drive pulses set with a greater pulse width is set with a rectangular wave pattern.

Abstract: The invention provides a machine tool capable of facilitating a process of switching product ejecting apparatuses. The machine tool comprises a spindle which rotates a workpiece around an axis of the spindle, an actuator which reciprocates a rod arranged parallel to the axis of the spindle, and a coupler switched between a coupling position and a standby position. The coupler connects the rod and an ejecting shaft inserted in the spindle when held in the coupling position. The coupler is not connected to at least the ejecting shaft when held in the standby position. The ejecting shaft along with the coupler is moved in the direction of the axis of the spindle according to reciprocation of the rod when the coupler is held in the coupling position.

Abstract: A computer implemented method of generating new chemical compounds is provided. The method includes preparing a data-driven substructure feature vector for each of a plurality of chemical compounds for which a chemical or physical property is known. The method further includes preparing a predefined component feature vector, creating a regression model to predict a target value for the chemical or physical property, and performing a search algorithm to identify substructure features that affect the target value for the chemical or physical property. The method further includes generating a candidate structure having the target value for the chemical or physical property, and synthesizing the candidate structure.

Abstract: An optical structure includes a substrate including a cavity on a first surface of the substrate, an optical component on the substrate and an adhesive applied to a side of the optical component to fix the optical component to the substrate. The optical component includes a recess on a second surface of the optical component, the second surface is opposed to the first surface of the substrate, and the recess is provided along an edge of the second surface.

Abstract: A method and system are provided for predicting chemical structures. The method includes receiving, at a user interface, intended structural feature values and intended chemical property values, as vectors. The method further includes constructing, by a hardware processor, a prediction model, wherein the prediction model predicts other structural feature values from the intended structural feature values and the intended chemical property values, and automatically configuring, by the hardware processor, at least one chemical structure candidate from the other structural feature vectors.

Abstract: Novel compounds having D3 receptor antagonistic activity are provided. A compound represented by formula (I): wherein ring A is a heterocycle, X1 is each independently CR4aR4b, X2 is each independently CR4cR4d, Y1 and Y2 are each independently a carbon atom or a nitrogen atom, L is —N(R6)—C(?O)— or the like, W is cyclyl or the like, R2 and R3 are each independently substituted or unsubstituted alkyl or the like, R1a, R1b, R4a to R4d, and R6 are each independently hydrogen atoms or the like, p is 1 or 2, q is an integer of 1 to 3, n is an integer of 1 to 4, s is an integer of 0 to 4, or a pharmaceutically acceptable salt thereof.

Abstract: The reservoir tank includes a reservoir body which reserves a fluid in an inner portion thereof formed to be in a hollow box shape. The reservoir body includes a port extending outward, a reservoir chamber which reserves the fluid and a port chamber which volume is smaller than that of the reservoir chamber and is in fluid communication with the port and a first communication passage positioned at a portion lower than a changeable liquid surface of the fluid reserved in the reservoir chamber in a vertical direction and provided at the first partition portion to allow the fluid communication between the reservoir chamber and the port chamber and wherein the port chamber and the port are kept being a state in which they are filled with the fluid supplied from the reservoir chamber via the first communication passage.

Abstract: The invention provides a machine tool capable of facilitating a process of switching product ejecting apparatuses. The machine tool comprises a spindle which rotates a workpiece around an axis of the spindle, an actuator which reciprocates a rod arranged parallel to the axis of the spindle, and a coupler switched between a coupling position and a standby position. The coupler connects the rod and an ejecting shaft inserted in the spindle when held in the coupling position. The coupler is not connected to at least the ejecting shaft when held in the standby position. The ejecting shaft along with the coupler is moved in the direction of the axis of the spindle according to reciprocation of the rod when the coupler is held in the coupling position.

Abstract: An optical structure is presented. The optical structure includes a substrate including a cavity on a first surface of the substrate. The optical structure further includes an optical component on the substrate, the optical component including a second surface opposed to the first surface of the substrate. The optical structure also includes an adhesive in a gap between the first surface of the substrate and the second surface of the optical component affixing the optical component to the substrate, wherein at least one of the first surface of the substrate and the second surface of the optical component includes a predetermined portion arranged around the cavity, wherein the predetermined portion prevents the adhesive from infiltrating.