Abstract: The present invention provides a method for producing megakaryocytes that have an increased capacity to produce platelets, the method comprising a step of culturing, under conditions that cause the death of cells that do not express a gene that is specifically expressed by megakaryocytes, cells that have the capacity to differentiate into megakaryocytes.

Abstract: An image forming apparatus includes image bearers, motors, a reference position detector, and processing circuitry. The circuitry senses a density of a toner image on each bearer; forms an image pattern and senses, based on a detection result of the detector and a sensing result of the density, density unevenness in a rotation cycle and a phase of the density unevenness with respect to a rotational position reference of each bearer; calculates a target phase based on the phase sensed; calculates a relative phase difference based on a rotational position and the target phase of each bearer; selects, as a reference image bearer, an image bearer having a minimum phase correction value, based on a calculation result of the difference; and controls the rotational position of each of the other image bearers with respect to the reference image bearer to the phase correction value, with the motors being driven.

Abstract: A speed reducing mechanism according to the present invention includes: a speed reducing unit for decelerating input rotation; an accelerating unit for accelerating rotation output from the speed reducing unit; and a brake unit for applying a braking force for braking the accelerating unit.

Abstract: A conveying roller, a conveyor device, and an inclined conveyor for objects. A conveying roller comes into contact with an object and moves the object, the conveying roller including: a core member and a plurality of blade-shaped pieces, the blade-shaped piece being elastically deformable and being provided around the core member.

Abstract: An information processing device according to the present application includes a generation unit and a providing unit. The generation unit uses a model that is trained to learn a relationship between a criterion for classifying users of a first company and a criterion for classifying users of a second company to generate a criterion (common key) for classifying the users of the second company into a first category, from the criterion for classifying the users of the first company into the first category. The providing unit provides a criterion generated by the generation unit.

Abstract: Healthy functional platelets are mass produced. A method for producing platelets, comprising: (1) a culture step of culturing megakaryocytes in a platelet producing medium in the presence of mechanical stress and platelet production promoting factors including MIF, NRDc, IGFBP2, TSP-1, PAI-1, and CCL5, and (2) a harvest step of harvesting the platelets obtained by the culture step; wherein the culture step comprises: (a) a step of promoting a release of the platelet production promoting factors from megakaryocytes by mechanical stress; and/or (b) a step of externally adding platelet production promoting factors including MIF, NRDc, and IGFBP2.

Abstract: A novel functional panel that is highly convenient, useful, or reliable is provided. The functional panel includes a base material and a pair of pixels, and the base material covers the pair of pixels and has a light-transmitting property. The pair of pixels includes one pixel and another pixel, and the one pixel includes a light-emitting device and a first microlens. The light-emitting device emits light toward the base material, and the first microlens is interposed between the base material and the light emission and converges light. The first microlens includes a first surface and a second surface; the second surface is closer to the light-emitting device than the first surface is; and the second surface has a smaller radius of curvature than the first surface. The other pixel includes a photoelectric conversion device and a second microlens. The second microlens is interposed between the base material and the photoelectric conversion and converges external light incident from the base material side.

Abstract: Provided is a liquid crystal display device capable of switching between a transparent state and a scattering state, reducing or preventing a decrease in transmittance in the transparent state, and reducing or preventing a decrease in luminance in the panel central portion in the scattering state. The liquid crystal display device includes, sequentially from its viewing surface side toward its back surface side: a first liquid crystal panel; a light source; and a second liquid crystal panel, the first liquid crystal panel including a polymer dispersed liquid crystal containing a polymer network and liquid crystal components, the light source being configured to irradiate a back surface side main surface of the first liquid crystal panel with light from an oblique direction.

Abstract: A non-transitory computer-readable storage medium storing therein an information management program for causing a computer to execute a process comprises: receiving property information indicating a reliability of a post uploaded on the Internet and a digital signature generated from the property information; and storing the property information, to which identification information of the post and the digital signature are added, in a storage.

Abstract: Provided is a vehicle undercover having well-balanced rigidity. A vehicle undercover 10 is provided with: a plate-shaped body 12 made of a porous material such as a fiber body or a foam; and a support body 14 supporting the plate-shaped body 12. The support body 14 has a groove-shaped first frame part 20 having a horizontal plate 20a and vertical plates 20b and 20b extending from both edges of the horizontal plate 20a. Further, the support body 14 has a second frame part 22 provided across the first frame part 20 and having a smaller dimension of protrusion toward the inside of a vehicle than the first frame part 20.

Abstract: The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating/preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.

Abstract: An abnormality detecting device relating to the present disclosure includes at least two first cover parts arranged next to each other in a circumferential direction; a plurality of electrode parts respectively supported by the first cover parts; a plurality of magnet parts provided inside of the first cover parts in the radial direction, where each magnet part is in contact with a corresponding one of the electrode parts; and at least two second cover parts provided between adjacent ones of the first cover parts in the circumferential direction. Each electrode part has an oil-repellent surface.

Abstract: A container includes a pouch formed of a film material and in which a lubricant composition with a worked penetration of 300 to 450 is filled and sealed, and a spout fixed to the pouch.

Abstract: An aspect of the present invention provides a speed reducer including a supporting block, an input gear rotatably supported on the supporting block, an intermediate gear meshing with the input gear, an output gear meshing with the intermediate gear, and a gear position changing mechanism configured to change a position of the intermediate gear relative to the input and output gears.

Abstract: A speed reducer according to the invention includes: a main speed reduction unit decelerating rotation from an input side and transmitting decelerated rotation to an output side; a fixed block coupled to the main speed reduction unit and rotatably supporting an input gear coupled to a rotary drive source; an output gear transmitting rotation of the input gear to an input side of the main speed reduction unit; and an intermediate gear meshing with the input gear and the output gear and rotatably supported by the fixed block.

Abstract: The present invention provides a therapeutic agent and a therapeutic method for cancer, etc., capable of exerting a more potent and sustained antitumor effect than existing FGFR4-selective tyrosine kinase inhibitors. The present invention is directed to a pharmaceutical combination for the treatment of cancer, characterized by comprising: a substance which inhibits or suppresses the tyrosine kinase activity of fibroblast growth factor receptor 4 (FGFR4), or a prodrug thereof, or a pharmacologically acceptable salt thereof, or a hydrate or solvate thereof; and an antibody against human DLK-1, which has in vivo antitumor activity, or an antibody fragment derived from the antibody.

Abstract: The present disclosure relates to a manufacturing method of a speed reducer. The speed reducer includes an outer tube, a shaft portion, an input shaft, a first bearing, a speed reducing portion, and an attachment member. The shaft portion has a first receiving surface and a shaft end surface. The outer tube has a second receiving surface. The first bearing has a first inner ring and a first outer ring. The first receiving surface contacts the first inner ring. The second receiving surface contacts the first outer ring. A first machining accuracy is obtained based on a first parallelism between the first receiving surface and the shaft end surface. A second machining accuracy is obtained based on a second parallelism between the second receiving surface and the flange mounting surface. The manufacturing method includes performing machining such that the first machining accuracy becomes higher than the second machining accuracy.

Abstract: The present disclosure relates to a manufacturing method of a speed reducer. The speed reducer includes an outer tube, a shaft portion, an input shaft, a first bearing, a speed reducing portion, and an attachment member. The shaft portion has a first receiving surface and a shaft end surface. The outer tube has a second receiving surface. The first bearing has a first inner ring and a first outer ring. The first receiving surface contacts the first inner ring. The second receiving surface contacts the first outer ring. A first machining accuracy is obtained based on a first parallelism between the first receiving surface and the shaft end surface. A second machining accuracy is obtained based on a second parallelism between the second receiving surface and the flange mounting surface. The manufacturing method includes performing machining such that the first machining accuracy becomes higher than the second machining accuracy.

Abstract: Provided is a status monitoring device for a speed reducer, including: at least one signal transmission unit for monitoring a status of at least one crankshaft of a speed reducer and transmitting a status signal; and a determination unit for determining a status of the speed reducer based on the status signal from the at least one signal transmission unit.

Abstract: Provided is a headgear including first and second holding parts that respectively hold first and second cooling members. In a worn state, the first and second holding parts are respectively positioned laterally to left and right carotid arteries. The headgear includes a headgear main body to be worn on a head and a neck cover that covers a neck, the first and second holding parts are provided in the neck cover, the first holding part is a first pocket that stores the first cooling member, the second holding part is a second pocket that stores the second cooling member, and the headgear includes a coupling part that detachably couples a left end part and a right end part of the neck cover.