Patents by Inventor Konosuke Fukai

Konosuke Fukai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant Marek's disease virus and vaccine
    Patent number: 5650153
    Abstract: There is provided a recombinant Marek's disease virus comprising the genomic DNA of an attenuated Marek's disease virus and a foreign gene from another source. The present recombinant virus can advantageously be used as an active ingredient for a multifunctional live vaccine, exhibiting not only the antigenicity and immunogenicity of the Marek's disease virus but also the properties ascribed to the foreign gene. Since the suitable host cell for the recombinant virus of the present invention is an avian cell which is available in a large quantity and not expensive, the recombinant virus of the present invention can be produced efficiently at low cost on a commercial scale.
    Type: Grant
    Filed: August 24, 1994
    Date of Patent: July 22, 1997
    Assignee: The Research Foundation for Microbial Diseases
    Inventors: Toyokazu Ishikawa, Sadao Manabe, Chisato Mori, Akihisa Takamizawa, Iwao Yoshida, Juichiro Osame, Keisuke Takaku, Konosuke Fukai
  • A DNA coding for a Flavivirus antigen
    Patent number: 5486473
    Abstract: There is disclosed a DNA which codes for an antigen comprising at least part of an amino acid sequence of the antigen of a flavivirus, which part contains at least one epitope of the flavivirus antigen. The present DNA can be used for producing the antigen easily and safely at low cost by means of recombinant DNA technique. The antigen produced using the present DNA can be used as an effective vaccine and diagnostic for Japanese encephalitis.
    Type: Grant
    Filed: February 9, 1994
    Date of Patent: January 23, 1996
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Hiroyuki Fujita, Iwao Yoshida, Mitsuo Takagi, Sadao Manabe, Konosuke Fukai
  • Non-A, non-B hepatitis virus antigen peptide
    Patent number: 5298394
    Abstract: Disclosed is a non-A, non-B hepatitis virus antigen peptide which exhibits antigen-antibody reaction specificity with at least one of sera from a convalescent patient having acute non-A, non-B hepatitis and sera from a patient having chronic non-A, non-B hepatitis. By the use of the antigen peptide of the present invention, not only the diagnosis of non-A, non-B hepatitis but also the screening of blood for transfusion can be achieved with ease and high reliability. The antigen peptide of the present invention may also be used as the basis for a vaccine against non-A, non-B hepatitis.
    Type: Grant
    Filed: March 2, 1993
    Date of Patent: March 29, 1994
    Assignee: The Research Foundation for Microbial Diseases
    Inventors: Terukatsu Arima, Konosuke Fukai
  • Non-A, non-B hepatitis virus antigen peptide
    Patent number: 5275947
    Abstract: Disclosed is a non-A, non-B hepatitis virus antigen peptide which exhibits antigen-antibody reaction specificity with at least one of sera from a convalescent patient having acute non-A, non-B hepatitis and sera from a patient having chronic non-A, non-B hepatitis. By the use of the antigen peptide of the present invention, not only the diagnosis of non-A, non-B hepatitis but also the screening of blood for transfusion can be achieved with ease and high reliability. The antigen peptide of the present invention may also be used as the basis for a vaccine against non-A, non-B hepatitis.
    Type: Grant
    Filed: March 2, 1993
    Date of Patent: January 4, 1994
    Assignee: The Research Foundation for Microbial Disease of Osaka University
    Inventors: Terukatsu Arima, Konosuke Fukai
  • Non-A, non-B hepatitis virus antigen peptide
    Patent number: 5191064
    Abstract: Disclosed is a non-A, non-B hepatitis virus antigen peptide which exhibits antigen-antibody reaction specificity with at least one of sera from a convalescent patient having acute non-A, non-B hepatitis and sera from a patient having chronic non-A, non-B hepatitis. By the use of the antigen peptide of the present invention, not only the diagnosis of non-A, non-B hepatitis but also the screening of blood for transfusion can be achieved with ease and high reliability. The antigen peptide of the present invention may also be used as the basis for a vaccine against non-A, non-B hepatitis.
    Type: Grant
    Filed: August 31, 1989
    Date of Patent: March 2, 1993
    Assignee: The Research Foundation for Microbial Diseases (Osaka University)
    Inventors: Terukatsu Arima, Konosuke Fukai
  • Flavivirus antigen
    Patent number: 4810492
    Abstract: There is disclosed an antigen comprising at least part of an amino acid sence of the antigen of a flavivirus, which part contains at least one of epitopes of the flavivirus antigen. The present antigen can be produced easily and safely at low cost by means of recombinant DNA technique. The present antigen can be used as an effective vaccine and diagnostic for Japanese encephalitis.
    Type: Grant
    Filed: November 19, 1986
    Date of Patent: March 7, 1989
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Hiroyuki Fujita, Iwao Yoshida, Mitsuo Takagi, Sadao Manabe, Konosuke Fukai