Patents by Inventor Konstantinos Agrios

Konstantinos Agrios has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-METHYLPROP ANAMIDES AND THEIR USE AS PHARMACEUTICALS
    Publication number: 20100137401
    Abstract: The present invention relates to inhibitors of 11-? hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-? hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
    Type: Application
    Filed: February 2, 2010
    Publication date: June 3, 2010
    Applicant: Incyte Corporation
    Inventors: Wenqing Yao, Colin Zhang, Jincong Zhuo, Meizhong Xu, Konstantinos Agrios, Brian Metcalf
  • 2-methylprop anamides and their use as pharmaceuticals
    Patent number: 7687665
    Abstract: The present invention relates to inhibitors of 11-? hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-? hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: March 30, 2010
    Assignee: Incyte Corporation
    Inventors: Wenqing Yao, Colin Zhang, Jincong Zhuo, Meizhong Xu, Konstantinos Agrios, Brian Metcalf
  • Amido compounds and their use as pharmaceuticals
    Publication number: 20060009471
    Abstract: The present invention relates to inhibitors of 11-? hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-? hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
    Type: Application
    Filed: June 23, 2005
    Publication date: January 12, 2006
    Inventors: Wenqing Yao, Meizhong Xu, Colin Zhang, Konstantinos Agrios, Brian Metcalf, Jincong Zhuo
  • Amido compounds and their use as pharmaceuticals
    Publication number: 20060009491
    Abstract: The present invention relates to inhibitors of 11-? hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-? hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
    Type: Application
    Filed: June 23, 2005
    Publication date: January 12, 2006
    Inventors: Wenqing Yao, Colin Zhang, Konstantinos Agrios, Brian Metcalf, Jincong Zhuo
  • Pyrano, piperidino, and thiopyrano compounds and methods of use
    Patent number: 6642222
    Abstract: The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: November 4, 2003
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Konstantinos A. Agrios, Robert J. Altenbach, Irene Drizin, Michael E. Kort
  • Pyrano piperidino and thiopyrano compounds and methods of use
    Publication number: 20030055035
    Abstract: 1
    Type: Application
    Filed: May 3, 2000
    Publication date: March 20, 2003
    Inventors: Willilam A. Carroll, Konstantinos A. Agrios, Robert J. Altenbach, Irene Drizin, Michael E. Kort
  • Dihydronaphthyridine potassium channel openers
    Publication number: 20020099070
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: August 2, 2001
    Publication date: July 25, 2002
    Inventor: Konstantinos Agrios
  • Pyrano, piperidino, and thiopyrano compounds and methods of use
    Patent number: 6191140
    Abstract: The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: February 20, 2001
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Konstantinos A. Agrios, Robert J. Altenbach, Irene Drizin, Michael E. Kort