Patents by Inventor Konstantinos Ritis

Konstantinos Ritis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Complement-mediated thrombophilic assay
    Patent number: 8563259
    Abstract: A method for assessing the presence of an acquired thrombophilia disorder in a patient exhibiting hypercoagulation is disclosed.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: October 22, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, Konstantinos Ritis
  • Method of inhibiting biomaterial-induced procoagulant activity using complement inhibitors
    Patent number: 8445190
    Abstract: Methods for reducing or eliminating biomaterial-induced procoagulant activity in blood subjected to extracorporeal treatment that exposes the blood to the biomaterial are disclosed. The methods involve treatment of the blood, or the extracorporeal biomaterial, or both, with a complement inhibitor to inhibit C5a/C5aR-mediated tissue factor formation in the blood.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: May 21, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, Konstantinos Ritis
  • METHOD OF INHIBITING BIOMATERIAL-INDUCED PROCOAGULANT ACTIVITY USING COMPLEMENT INHIBITORS
    Publication number: 20110269113
    Abstract: Methods for reducing or eliminating biomaterial-induced procoagulant activity in blood subjected to extracorporeal treatment that exposes the blood to the biomaterial are disclosed. The methods involve treatment of the blood, or the extracorporeal biomaterial, or both, with a complement inhibitor to inhibit C5a/C5aR-mediated tissue factor formation in the blood.
    Type: Application
    Filed: September 29, 2009
    Publication date: November 3, 2011
    Inventors: John D. Lambris, Konstantinos Ritis
  • Method Of Treating Acute Respiratory Distress Syndrome
    Publication number: 20110142837
    Abstract: Methods for treating and/or alleviating acute respiratory distress syndrome in an individual diagnosed with or at risk of developing acute respiratory distress syndrome are disclosed. The methods comprise administering a therapeutically effective amount of a complement inhibitor or a TNF-alpha inhibitor to the individual, wherein the complement inhibitor or the TNF-alpha inhibitor reduces or prevents tissue factor production in alveolar neutrophils, thereby treating the ARDS, or delaying or preventing onset of ARDS.
    Type: Application
    Filed: July 17, 2008
    Publication date: June 16, 2011
    Applicants: TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, DEMOCRITUS UNIVESITY OF THRACE
    Inventors: John D. Lambris, Konstantinos Ritis
  • Complement-Mediated Thrombophilic Assay
    Publication number: 20100311086
    Abstract: A method for assessing the presence of an acquired thrombophilia disorder in a patient exhibiting hypercoagulation is disclosed.
    Type: Application
    Filed: June 25, 2008
    Publication date: December 9, 2010
    Inventors: John D. Lambris, Konstantinos Ritis