Patents by Inventor Kosuke Kuwabara

Kosuke Kuwabara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120037410
    Abstract: A thermoplastic resin composition including a polyphenylene ether-based polymer having hydroxyl groups in its chemical structure and having 2,6-dimethylphenylene ether as a repeating unit, an isocyanate compound having a plurality of isocyanate groups in its structure; or a reaction product of the polyphenylene ether-based polymer having 2,6-dimethylphenylene ether as a repeating unit and the isocyanate compound having a plurality of isocyanate groups in its structure; and a hydrogenated styrene-based elastomer, and an adhesive film and a wiring film using the same are disclosed.
    Type: Application
    Filed: August 10, 2011
    Publication date: February 16, 2012
    Inventors: Satoru Amou, Kosuke Kuwabara, Nobuhito Akutsu, Tomiya Abe
  • Patent number: 8113816
    Abstract: An imprint device transfers a finely patterned structure created on a stamper onto a material to be patterned, by bringing the stamper and the material to be patterned in contact with each other. At least one chamfered edge portion is formed at least one of the stamper and the material to be patterned. The imprint device has a separating unit for holding the chamfered edge portion of at least one of the stamper and the material to be patterned, so as to separate the stamper from the material to be patterned.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: February 14, 2012
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Yasuhiko Tada, Masahiko Ogino, Hiroshi Yoshida, Takashi Ando, Kosuke Kuwabara
  • Patent number: 8089624
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: January 3, 2012
    Assignee: Hitachi, Ltd.
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Publication number: 20110135814
    Abstract: A functioning substrate with a group of columnar micro pillars characterized in that a first matrix of organic polymer and a group of columnar micro pillars of organic polymer extending from this matrix are provided. This group of columnar micro pillars has an equivalent diameter of 10 nm through 500 ?m and a height of 50 nm through 5000 ?m; and the ratio (H/D) of the equivalent diameter (D) to the height (H) of the group of columnar micro pillars is 4 or more.
    Type: Application
    Filed: February 16, 2011
    Publication date: June 9, 2011
    Inventors: Akihiro MIYAUCHI, Kosuke Kuwabara, Masahiko Ogino, Hiroshi Yoshida, Takashi Ando
  • Publication number: 20110058162
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
    Type: Application
    Filed: October 12, 2010
    Publication date: March 10, 2011
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Patent number: 7887723
    Abstract: It is an object of the present invention to provide a method which can easily and selectively modify specific sites on indentations or protrusions of indentation/protrusion structures fabricated by nano-imprinting. Pressing a mold having indentation/protrusion structures onto a polymer substrate comprising at least two layers of different chemical composition exposes the second layer, which has been covered by the outermost layer, in pillars formed as a result of the pressing. Site-specific chemical modification of the pillars can be achieved by formulating a desired chemical composition for the second layer beforehand, or by chemical modification of the exposed second layer cross-sections in the pillars.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: February 15, 2011
    Assignee: Hitachi, Ltd.
    Inventors: Kenji Murao, Kosuke Kuwabara, Masahiko Ogino
  • Patent number: 7888111
    Abstract: An object of the present invention is to provide a cell culture vessel which is simple in structure and easy to handle, and is capable of preventing damage to the cells when separated, promoting transport of nutrients and excretion of effete matter, and elevating the culturing efficiency improving effect by the structural features. In order to attain the above object, there is provided a cell culture vessel including a culture section provided with a plurality of projections having an equivalent diameter smaller than the cells to be cultured and the culture section side walls enclosing the culture section, wherein the distance between an arbitrary position on the culture section/side wall boundary line and the nearest projection is smaller than the diameter of the cells to be cultured. The effect of the projections in the vessel given to the cultured cells is enhanced.
    Type: Grant
    Filed: November 9, 2009
    Date of Patent: February 15, 2011
    Assignee: Hitachi, Ltd.
    Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Norihito Kuno
  • Patent number: 7834998
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: November 16, 2010
    Assignee: Hitachi, Ltd.
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Publication number: 20100220322
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the refection spectrum.
    Type: Application
    Filed: May 12, 2010
    Publication date: September 2, 2010
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Patent number: 7742165
    Abstract: The invention makes it possible to measure binding of a biochemical substance with a high throughput and with high sensitivity using a small cell capable of being filled with a small amount of chemical solution. A space between a first substrate and a second substrate such that probes are immobilized on their mutually facing planes is used as a cell that houses a specimen solution. Light is irradiated from a first substrate side, and reflected light is subjected to spectroscopy. Binding of the target with the probe is detected by a wavelength shift in the reflection spectrum.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: June 22, 2010
    Assignee: Hitachi, Ltd.
    Inventors: Toru Fujimura, Kosuke Kuwabara, Tatsuro Ide
  • Patent number: 7691625
    Abstract: An object of the present invention is to provide a cell culture vessel which is simple in structure and easy to handle, and is capable of preventing damage to the cells when separated, promoting transport of nutrients and excretion of effete matter, and elevating the culturing efficiency improving effect by the structural features. In order to attain the above object, there is provided a cell culture vessel including a culture section provided with a plurality of projections having an equivalent diameter smaller than the cells to be cultured and the culture section side walls enclosing the culture section, wherein the distance between an arbitrary position on the culture section/side wall boundary line and the nearest projection is smaller than the diameter of the cells to be cultured. The effect of the projections in the vessel given to the cultured cells is enhanced.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: April 6, 2010
    Assignee: Hitachi, Ltd.
    Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Norihito Kuno
  • Publication number: 20100055779
    Abstract: An object of the present invention is to provide a cell culture vessel which is simple in structure and easy to handle, and is capable of preventing damage to the cells when separated, promoting transport of nutrients and excretion of effete matter, and elevating the culturing efficiency improving effect by the structural features. In order to attain the above object, there is provided a cell culture vessel including a culture section provided with a plurality of projections having an equivalent diameter smaller than the cells to be cultured and the culture section side walls enclosing the culture section, wherein the distance between an arbitrary position on the culture section/side wall boundary line and the nearest projection is smaller than the diameter of the cells to be cultured. The effect of the projections in the vessel given to the cultured cells is enhanced.
    Type: Application
    Filed: November 9, 2009
    Publication date: March 4, 2010
    Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Norihito Kuno
  • Patent number: 7655457
    Abstract: It is an object of this invention to provide a cell culture vessel which has a simple and convenient structure, can prevent the injury on the cells at the time of peeling, and accelerates the transportation of nutrients and discharge of waste materials. In order to solve the problem mentioned above, the cell culture vessel of this invention has protrusions having a corresponding diameter not smaller than 10 nm and not greater than 10 ?m and a height not smaller than 10 nm and not greater than 1 mm on the surface of the cell culture vessel. The protrusions make the culture fluid permeate into the under part of the cells, accelerate the supply of nutrients and discharge of waste materials, and makes the contact between the cells and the vessel as a point-contact and thereby prevents the cells from the injury which the cells undergo at the time of peeling.
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: February 2, 2010
    Assignee: Hitachi, Ltd.
    Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Masahiko Ogino, Takashi Ando
  • Patent number: 7520742
    Abstract: A pillar with a high aspect ratio is transferred by a nanoprinting method. In order to form a fine structure on a substrate, a nanoprinting apparatus heats and presses the substrate and a mold with a fine concave-convex pattern formed thereon, the mold having a mechanism for transferring and applying a mold-releasing agent. A method for transferring a fine structure using the aforementioned nanoprinting apparatus.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: April 21, 2009
    Assignee: Hitachi, Ltd.
    Inventors: Shigehisa Motowaki, Akihiro Miyauchi, Masahiko Ogino, Kosuke Kuwabara
  • Publication number: 20080229948
    Abstract: An imprint device transfers a micropattern created on a stamper onto a material to be transferred, by bringing the stamper and the material to be transferred into contact with each other. The imprint device has a flow passage for discharging a fluid to a rear surface of the stamper or the material to be transferred, to thereby bend the stamper or the material to be transferred.
    Type: Application
    Filed: January 25, 2008
    Publication date: September 25, 2008
    Inventors: Ryuta Washiya, Takashi Ando, Masahiko Ogino, Hideaki Kataho, Akihiro Miyauchi, Kosuke Kuwabara
  • Patent number: 7374417
    Abstract: A stamper and a transfer apparatus that utilizes the stamper, which is capable of accurately transferring its own pattern onto an article, such as a substrate, without being affected by any distribution of convex portions on the stamper surface or any contour of the substrate. The stamper has a fine concave-convex pattern on a surface thereof for forming a fine structure on a substrate using a pressing machine. The stamper is flexible and includes a buffer formed on an opposite side to the side on which the concave-convex pattern is formed. The buffer has a longitudinal distribution of moduli of elasticity.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: May 20, 2008
    Assignee: Hitachi, Ltd.
    Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Masahiko Ogino, Sigehisa Motowaki
  • Patent number: 7341441
    Abstract: Provided is a nanoprint apparatus in which a substrate and a mold formed on its surface with fine concavities and convexities are heated and pressed with each other through the intermediary of a buffer member interposed therebetwen, including a mechanism for successively replacing the buffer member with new one at each time which the mold and the substate are heated and pressed, thereby it is possible to form a fine structure on the substrate.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: March 11, 2008
    Assignee: Hitachi Industries Co., Ltd.
    Inventors: Masahiko Ogino, Akihiro Miyauchi, Shigehisa Motowaki, Kosuke Kuwabara
  • Publication number: 20080057578
    Abstract: There is provided a technology for simple three-dimensional culturing of cartilage cells. The technology includes a method for culturing cartilage cells which comprises seeding cartilage cells 1 on a plurality of projected portions 21 of a culturing substrate 2 having a culture surface on which the projected portions 21 having an equivalent diameter and an interval which are smaller than the equivalent diameter of the cartilage cells 1 to be cultured, placing the culture substrate 2 having the cartilage cells 1 in a culture vessel, and culturing the cartilage cells to form aggregates of cartilage cells.
    Type: Application
    Filed: August 24, 2007
    Publication date: March 6, 2008
    Inventors: Kosuke Kuwabara, Akihiro Miyauchi, Toshimasa Uemura
  • Publication number: 20080041248
    Abstract: The present invention provides an imprint apparatus transferring a surface structure of a stamper to material to be patterned by allowing the stamper come in contact with the material to be patterned. The imprint apparatus includes a holding means that holds the material to be patterned and the stamper with a distance therebetween, a pressure reduction means that reduces pressure of a chamber in which the material to be patterned and the stamper are placed, and an alignment means that aligns the stamper with the material to be patterned.
    Type: Application
    Filed: July 6, 2007
    Publication date: February 21, 2008
    Inventors: KOSUKE KUWABARA, Takashi Ando, Masahiko Ogino, Hiroshi Yoshida, Yasuhiko Tada
  • Publication number: 20080029931
    Abstract: An imprint device transfers a finely patterned structure created on a stamper onto a material to be patterned, by bringing the stamper and the material to be patterned in contact with each other. At least one chamfered edge portion is formed at least one of the stamper and the material to be patterned. The imprint device has a separating unit for holding the chamfered edge portion of at least one of the stamper and the material to be patterned, so as to separate the stamper from the material to be patterned.
    Type: Application
    Filed: July 6, 2007
    Publication date: February 7, 2008
    Inventors: Yasuhiko TADA, Masahiko OGINO, Hiroshi YOSHIDA, Takashi ANDO, Kosuke KUWABARA