Patents by Inventor Kotha Subbaramaiah

Kotha Subbaramaiah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CROWN-LIKE STRUCTURES AS A BIOMARKER FOR CANCER RISK AND CANCER PROGNOSIS
    Publication number: 20130324617
    Abstract: Chronic inflammation increases the risk of several epithelial malignancies. The present invention provides methods for determining cancer risk in a patient which comprises detecting the presence of crown-like structures (CLS), methods for treating cancer associated with CLS presence, methods for determining cancer risk in a patient by quantifying the number of CLS in a sample of adipose tissue of the patient, methods of determining prognosis of a patient with breast cancer or other cancers by detecting CLS, and screening methods for anti-cancer agents or agents that inhibit or reduce CLS formation or consequences thereof.
    Type: Application
    Filed: February 11, 2012
    Publication date: December 5, 2013
    Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER, CORNELL UNIVERSITY
    Inventors: Andrew J. Dannenberg, Kotha Subbaramaiah, Clifford Hudis
  • Treatment of HPV caused diseases
    Patent number: 7183316
    Abstract: Human papillomavirus (HPV) protein expression is downregulated in patients infected with HPV by administration of PPAR? ligand, selective inhibitor of cyclooxygenase-2 (COX-2), diaryl heterocycle, inhibitor of HPV protein from a natural source and/or certain non-steroidal anti-inflammatory drugs.
    Type: Grant
    Filed: March 14, 2002
    Date of Patent: February 27, 2007
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Andrew J. Dannenberg, Kotha Subbaramaiah
  • Multifunctional COX-2 inhibitors
    Publication number: 20050031537
    Abstract: Selective inhibitors of COX-2 and selective inhibitors of COX-1 are screened for COX protein independent therapeutic activity. Compounds passing screening testing are indicated for treatment of those having or at risk for cancer, Alzheimer's disease and atherosclerosis.
    Type: Application
    Filed: July 9, 2003
    Publication date: February 10, 2005
    Inventors: Andrew Dannenberg, Kotha Subbaramaiah
  • Treatment of HPV caused diseases
    Publication number: 20020164385
    Abstract: Human papillomavirus (HPV) protein expression is downregulated in patients infected with HPV by administration of PPAR&ggr; ligand, selective inhibitor of cyclooxygenase-2 (COX-2), diaryl heterocycle, inhibitor of HPV protein from a natural source and/or certain non-steroidal anti-inflammatory drugs.
    Type: Application
    Filed: March 14, 2002
    Publication date: November 7, 2002
    Inventors: Andrew J. Dannenberg, Kotha Subbaramaiah
  • Treating cancers associated with overexpression of HER-2/neu
    Patent number: 6403630
    Abstract: Cancers associated with overexpression of HER-2/neu are treated with a selective inhibitor of cyclooxygenase-2 as the sole treating agent or said inhibitor in combination regimen with HERCEPTIN® and/or standard therapy. Uses include adjuvant therapy for HER-2/neu positive breast cancer and treatment of HER-2/neu positive breast cancer that has metastasized.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: June 11, 2002
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Andrew J. Dannenberg, Kotha Subbaramaiah
  • Treating cancers associated with overexpression of class I family of receptor tyrosine kinases
    Patent number: 6291496
    Abstract: Cancer associated with overexpression of class I family of receptor tyrosine kinases, e.g., with overexpresssion of HER-2/neu or overexpression of epidermal growth factor receptor, are treated with strongly binding PPAR&ggr; ligands.
    Type: Grant
    Filed: December 27, 1999
    Date of Patent: September 18, 2001
    Inventors: Andrew J. Dannenberg, Kotha Subbaramaiah