Abstract: A mold clamping device of an injection molding machine supports a motor fixing member configured to fix a mold opening/closing motor to a rear platen, on a base frame through a support member and slide plates. When viewed from a direction of a drive shaft of the mold opening/closing motor, the width of the support member is formed to progressively increase outwardly from the motor fixing member toward the base frame, and on a portion of the support member that is located on the base frame side, the slide plates are provided at at least both ends of the portion in a width direction of the support member.

Abstract: The present invention aims to elucidate a polynucleotide as a novel responsible gene for cancer and aims to thus provide a method for detecting the polynucleotide and a polypeptide encoded by the polynucleotide and a detection kit, a probe set, and a primer set for the detection. The present invention also aims to provide a pharmaceutical composition for treating cancer. The method detects a fusion gene composed of a portion of an FGFR3 gene and a portion of a TACC3 gene or a fusion protein encoded by the fusion gene. The primer set, the probe set, or the detection kit comprises a sense primer and a probe set designed from the portion encoding FGFR3 and an antisense primer and a probe set designed from the portion encoding TACC3. Since an inhibitor of the polypeptide exhibits antitumor effect, a pharmaceutical composition for treating cancer which is positive for either the fusion gene or the polypeptide is provided.

Abstract: A mold clamping device of an injection molding machine supports a motor fixing member configured to fix a mold opening/closing motor to a rear platen, on a base frame through a support member and slide plates. When viewed from a direction of a drive shaft of the mold opening/closing motor, the width of the support member is formed to progressively increase outwardly from the motor fixing member toward the base frame, and on a portion of the support member that is located on the base frame side, the slide plates are provided at at least both ends of the portion in a width direction of the support member.

Abstract: The present invention aims to elucidate a polynucleotide as a novel responsible gene for cancer and aims to thus provide a method for detecting the polynucleotide and a polypeptide encoded by the polynucleotide and a detection kit, a probe set, and a primer set for the detection. The present invention also aims to provide a pharmaceutical composition for treating cancer. The method detects a fusion gene composed of a portion of an FGFR3 gene and a portion of a TACC3 gene or a fusion protein encoded by the fusion gene. The primer set, the probe set, or the detection kit comprises a sense primer and a probe set designed from the portion encoding FGFR3 and an antisense primer and a probe set designed from the portion encoding TACC3. Since an inhibitor of the polypeptide exhibits antitumor effect, a pharmaceutical composition for treating cancer which is positive for either the fusion gene or the polypeptide is provided.

Abstract: [Problem] The present invention aims to elucidate a polynucleotide as a novel responsible gene for cancer and aims to thus provide a method for detecting the polynucleotide and a polypeptide encoded by the polynucleotide and a detection kit, a probe set, and a primer set for the detection. The present invention also aims to provide a pharmaceutical composition for treating cancer. [Means for Solution] The method detects a fusion gene composed of a portion of an FGFR3 gene and a portion of a TACC3 gene or a fusion protein encoded by the fusion gene. The primer set, the probe set, or the detection kit comprises a sense primer and a probe set designed from the portion encoding FGFR3 and an antisense primer and a probe set designed from the portion encoding TACC3. Since an inhibitor of the polypeptide exhibits antitumor effect, a pharmaceutical composition for treating cancer which is positive for either the fusion gene or the polypeptide is provided.

Abstract: [Problem] The present invention aims to elucidate a polynucleotide as a novel responsible gene for cancer and aims to thus provide a method for detecting the polynucleotide and a polypeptide encoded by the polynucleotide and a detection kit, a probe set, and a primer set for the detection. The present invention also aims to provide a pharmaceutical composition for treating cancer. [Means for Solution] The method detects a fusion gene composed of a portion of an FGFR3 gene and a portion of a TACC3 gene or a fusion protein encoded by the fusion gene. The primer set, the probe set, or the detection kit comprises a sense primer and a probe set designed from the portion encoding FGFR3 and an antisense primer and a probe set designed from the portion encoding TACC3. Since an inhibitor of the polypeptide exhibits antitumor effect, a pharmaceutical composition for treating cancer which is positive for either the fusion gene or the polypeptide is provided.

Abstract: An output circuit includes a first output transistor disposed between a higher-potential power supply terminal and an external output terminal, a current flowing from the source of the first output transistor to the drain thereof being controlled on the basis of an external input signal; a second output transistor disposed between a lower-potential power supply terminal and the external output terminal, a current flowing from the source of the second output transistor to the drain thereof being controlled on the basis of an external input signal; and a clamping transistor having a first terminal and a control terminal, the first terminal and the control terminal being coupled to the gate of the first output transistor, and a second terminal coupled to the drain of the first output transistor.

Abstract: A display panel driver is provided with: first and second amplifiers; first to n-th even output nodes, n being an integer of two or more; first to n-th odd output nodes; first and second output pads connected to data lines of a display panel, respectively; first to n-th switch blocks; first to n-th even electrostatic protection resistors; and first to n-th odd electrostatic protection resistors. The i-th switch block out of the first to n-th switch blocks is configured to switch connections between the first and second amplifiers and i-th even and odd electrostatic protection resistors out of the first to n-th even and odd electrostatic protection resistors. The first to n-th even electrostatic protection resistors are connected between the first to n-th even output nodes and the first output pad, respectively. The first to n-th odd electrostatic protection resistors are connected between the first to n-th odd output nodes and the second output pad, respectively.

Abstract: A differential amplifier circuit includes: an NMOS transistor pair connected with a non-inversion input terminal and an inversion input terminal; a PMOS transistor pair connected with the non-inversion input terminal and the inversion input terminal; and an output circuit section. The PMOS transistor pair includes first and second PMOS transistors, and the NMOS transistor pair includes first and second non-doped type NMOS transistors as a depletion type of NMOS transistors in which a channel region is formed in a P-type substrate without a P well. The output circuit section includes a first current mirror of a folded cascode type connected with the first and second non-doped type NMOS transistors, and outputs an output voltage in response to a current from the first current mirror.

Abstract: In an operational amplifier, a control unit switches an operation mode between first and second operation modes. A first output drive stage circuit section is configured to amplify a first input signal differentially-amplified by a first or a second input differential stage circuit section to output as a first drive voltage, similar to a second output drive stage circuit section. First and second power supplies: supply voltages in a first voltage range to the first differential stage circuit section and the first output drive stage circuit section in the first operation mode, supply voltages in the first voltage range to the second differential stage circuit section and the first output drive stage circuit section in the second operation mode, similar to third and fourth power supplies. The drive voltage on each of the first and second output nodes is fed back.

Abstract: It was found that a new fusion gene of a portion of the KIF5B gene and a portion of the RET gene, which is present in a portion of cancer patients, is a gene responsible for cancer. Based on this finding, detection methods of a polynucleotide as the gene and a polypeptide encoded by the polynucleotide were established. The detection methods involve detecting a fusion gene of a portion of the KIF5B gene and a portion of the RET gene, or a fusion protein encoded by such a fusion gene. The primer sets and the detection kits comprise sense primers designed from a portion encoding KIF5B and antisense primers designed from a portion encoding RET.

Abstract: An operational amplifier includes an input differential stage having one external input receiving an external input voltage and two outputs; and two output stages. A switch section is provided between inputs of the two output stages and the two outputs of the input differential stage, and is configured to alternately connect the two outputs of the input differential stage and inputs of a positive-only output stage of the two output stages; and the two outputs of the input differential stage and inputs of a negative-only output stage of the two output stages.

Abstract: A transmitter circuit includes a driver circuit including a non-inverting output terminal and an inverting output terminal for outputting a signal current, which has a loop direction that changes based upon an input signal, to the non-inverting output terminal and the inverting output terminal and an output-waveform control circuit for detecting a waveform edge of the input signal and responding by increasing the signal current temporarily. The output-waveform control circuit includes a first inverter circuit receiving a non-inverted input signal, a first capacitor including one end connected to an output terminal of the first inverter circuit and another end connected to the inverting output terminal, a second inverter circuit receiving an inverted input signal, and a second capacitor including one end connected to an output terminal of the second inverter circuit and another end connected to the non-inverting output terminal.

Abstract: A driving device that outputs signals of different polarities from plural output terminals includes: a first power source wire that connects power terminals of some of plural first output circuits each outputting a signal of one polarity and power terminals of some of plural second output circuits each outputting a signal of the other polarity; and a second power source wire that connects power terminals of the rest of the plural first output circuits and power terminals of the rest of the plural second output circuits, the second power source wire being different from the first power source wire.

Abstract: An information system includes a plurality of forwarding nodes having a packet processing unit that performs processing of a received packet using a processing rule conforming to the received packet; and a control device causing plurality of forwarding nodes to operate as a virtual network by setting a processing rule in the forwarding nodes. The control device includes a virtual network path information storage unit that stores a correspondence relationship between the virtual network and a forwarding path configured by the forwarding nodes; and a virtual network control unit that identifies a virtual network affected by a change in a state of any forwarding node among the plurality of forwarding nodes, by referring to the virtual network path information storage unit.

Abstract: In an operational amplifier, a control unit switches an operation mode between first and second operation modes. A first output drive stage circuit section is configured to amplify a first input signal differentially-amplified by a first or a second input differential stage circuit section to output as a first drive voltage, similar to a second output drive stage circuit section. First and second power supplies: supply voltages in a first voltage range to the first differential stage circuit section and the first output drive stage circuit section in the first operation mode, supply voltages in the first voltage range to the second differential stage circuit section and the first output drive stage circuit section in the second operation mode, similar to third and fourth power supplies. The drive voltage on each of the first and second output nodes is fed back.

Abstract: An operational amplifier circuit includes: an input differential stage circuit supplied with power supply voltages in a first voltage range; and an output stage circuit supplied with power supply voltages in a second voltage range which is different from the first voltage range. The operational amplifier circuit amplifies a signal supplied to the input differential stage circuit and outputs the amplified signal from the output stage circuit to drive a load.

Abstract: In an operational amplifier includes: a control unit switches an operation mode between first and second operation modes. A first differential stage circuit section differentially-amplifies a first input signal supplied through a first input node in the first operation mode, and a second input signal supplied through the first input node in the second operation mode, similar to a second differential stage circuit section. A first output drive stage circuit section is configured to amplify the first input signal differentially-amplified by the first or second input differential stage circuit section to output as a first drive voltage, similar to a second output drive stage circuit section.

Abstract: The present invention enables rising and falling slew rates to be symmetrized and secures a drive current at the time of 2H inversion driving. An operational amplifier in accordance with one aspect of the present invention includes: a first output transistor and a second output transistor connected in series between a first power supply and a second power supply; an output terminal connected to a node between the first output transistor and the second output transistor; a phase-compensating element provided either between the gate of the first output transistor and the output terminal or between the gate of the second output transistor and the output terminal; and a floating current source connected between the gate of the first output transistor and the gate of the second output transistor.

Abstract: A differential amplifier circuit includes a first differential transistor pair, a second differential transistor pair, an adder section and an amplifying unit. The first differential transistor pair receives first and second input signals and an output signal as a third input signal, and the second differential transistor pair receives the first and second input signals and the output signal as a fourth input signal. The adder section adds first output signals from the first differential transistor pair and second output signals from the second differential transistor pair, and the amplifying unit amplifies an addition resultant signal from the adder section to output to the first and second differential transistor pairs.