Patents by Inventor Kouichiro Kawano

Kouichiro Kawano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for identifying and designing immunogenic peptides
    Patent number: 7348153
    Abstract: The invention provides a method for identifying peptides for use in increasing a cytotoxic T lymphocytes (CTL) response to an antigen. The method comprises the steps of comparing the amino acid sequence of the VH and/or VL portions of an anti-idiotypic monoclonal antibody to the amino acid sequence of an antigen to identify regions of homology between the Ab2 and the antigen, and to further identify an HLA binding motif in a homologous region. The identified homologous region which comprises an HLA binding motif defines a peptide sequence that is useful for stimulating a CTL response. Also provided are peptides identified by the method, and a method of using the peptides to stimulate a CTL response in an individual.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: March 25, 2008
    Assignees: Health Research, Inc., Board of Regents, The University of Texas Systems
    Inventors: Soldano Ferrone, Constantin Ioannides, James L. Murray, Kouichiro Kawano
  • Method for identifying and designing immunogenic peptides
    Publication number: 20060141532
    Abstract: The invention provides a method for identifying peptides for use in increasing a cytotoxic T lymphocytes (CTL) response to an antigen. The method comprises the steps of comparing the amino acid sequence of the VH and/or VL portions of an anti-idiotypic monoclonal antibody to the amino acid sequence of an antigen to identify regions of homology between the Ab2 and the antigen, and to further identify an HLA binding motif in a homologous region. The identified homologous region which comprises an HLA binding motif defines a peptide sequence that is useful for stimulating a CTL response. Also provided are peptides identified by the method, and a method of using the peptides to stimulate a CTL response in an individual.
    Type: Application
    Filed: November 23, 2005
    Publication date: June 29, 2006
    Inventors: Soldano Ferrone, Constantin Ioannides, James Murray, Kouichiro Kawano