Abstract: An oxygen permeable hard contact lens having an improved oxygen permeability and an improved hardness and rigidity and an improved refractive index, made of a polymer comprising a styrene containing a silyl or siloxanyl group having at most 15 silicon atoms.

Abstract: The present invention relates to an air-conditioning and an environmental control device for manufacturing plants of integrated circuits, chemicals and foods, hospitals, etc. where clean air is required. In this environmental control device, controlled air blows out from one side and is absorbed into the other side of the room. The blowing surface and the absorbing surface are divided on the basis of the predetermined module. Ventilating units are formed in a suitable size to conform to the module. Because of the construction, the controlling system of temperature or cleanliness of the air in the environmental control room can be rearranged to an optional one by replacing or changing positions of the ventilating units. Even if a controlling system is rearranged to an optional one, the room should be divided into a supply chamber, a mixing chamber, an environmental control chamber and a return chamber from one side to the opposite side of the room, so that air conditioned can flow as required.

Abstract: The stability of reception of information signals in a low-quality radio communication circuit is notably improved by a method and apparatus of diversity reception which, by means of the local oscillation frequencies of a plurality of receiving systems, permits one or more coherently interrelated received signals to be phase-locked in the phase-lock loops of the respective receiving systems and which, when any of the phase-lock loops has accidentally lost the phase-lock of the received signals, enables the lost phase-lock loop to resume normal phase-lock by borrowing and using, as its own local oscillation frequency, the local oscillation frequency of the phase-lock loop of one of the remaining receiving systems still locking the phases of the received signals.

Abstract: The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.

Abstract: A method of coloring a water-absorbable plastic partially or totally in a single color or multiple colors in such a manner that no migration or separation of the coloring agents used can take place. A copolymer of a coupler monomer and a water-absorbable plastic monomer, a polymer of a coupler polymer and a water-absorbable plastic monomer or a polymer of a coupler monomer and a water-absorbable plastic polymer is formed into an intermediate product shaped in the form of any desired final product. The intermediate product is immersed in an aqueous solution of a developer consisting of a diazonium double salt and allowed to swell, whereby the diazo-component of the developer penetrates into the plastic. The swollen product is then immersed in an aqueous acid or alkaline solution having an optimum pH value for coupling reaction to allow formation of an azoic dye on the plastic as a result of the coupling reaction.

Abstract: There are disclosed novel 4-substituted amino-.alpha.-aminomethylbenzyl alcohol derivatives represented by the formula: ##STR1## wherein X represents a halogen atom; Y represents a hydrogen atom or a halogen atom; R.sub.1 represents a lower alkyl group, a carbamoyl group, a mono- or di-lower alkyl-substituted carbamoyl group, a phenyl-substituted carbamoyl group, a lower alkoxycarbonyl group, a lower alkoxy-substituted lower alkoxycarbonyl group, a phenyl-substituted lower alkoxycarbonyl group, or a cycloalkyloxycarbonyl group; and R.sub.2 represents a lower alkyl group, a cycloalkyl group, or the group shown by the ##STR2## wherein R.sub.3 represents a hydrogen atom or a lower alkyl group and R.sub.4 represents a hydrogen atom, a hydroxy group, or a lower alkoxy group and the pharmaceutically acceptable nontoxic salts thereof.These compounds are antiasthmatic agents useful for the prophylaxis and treatment of asthma.

Abstract: A process of preparing a .DELTA..sup.3 -cephalosporanic acid ester derivative which comprises reacting a cephalosporanic acid sulfoxide ester derivative with thionyl halide or a phosphorous halide.The compounds prepared by the process of this invention are useful as intermediate compounds for preparing cephalosporin antibiotics and the compounds themselves are also potential antibacterials.

Abstract: 2-(Indenyloxymethyl) morpholine derivatives are disclosed. These derivatives are excellent in methamphetamine stereotyped increasing and antireserpine activities which are useful as antidepression agents.

Abstract: The compounds of this invention are strong central nervous system depressants, in particular strong antipsychotics.

Abstract: There are disclosed novel 4-substituted amino-.alpha.-aminomethylbenzyl alcohol derivatives represented by the formula: ##STR1## wherein X represents a halogen atom; Y represents a hydrogen atom or a halogen atom; R.sub.1 represents a lower alkyl group, a carbamoyl group, a mono- or di-lower alkyl-substituted carbamoyl group, a phenyl-substituted carbamoyl group, a lower alkoxycarbonyl group, a lower alkoxy-substituted lower alkoxycarbonyl group, a phenyl-substituted lower alkoxycarbonyl group, or a cycloalkyloxycarbonyl group; and R.sub.2 represents a lower alkyl group, a cycloalkyl group, or the group shown by the formula ##STR2## wherein R.sub.3 represents a hydrogen atom or a lower alkyl group and R.sub.4 represents a hydrogen atom, a hydroxy group, or a lower alkoxy group and the pharmaceutically acceptable nontoxic salts thereof.These compounds are antiasthmatic agents useful for the prophylaxis and treatment of asthma.

Abstract: Pyrazine derivatives by the formula ##STR1## are disclosed. In the above formula, R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom, a halogen atom, a hydroxy group, a lower alkoxy group, a phenyl lower alkoxy group, a phenoxy group, a mercapto group, a lower alkylthio group, a phenyl lower alkylthio group, a phenylthio group, an amino group, a substituted amino group, a lower alkyl group, a carbamoyl group or a sulfamoyl group; R.sup.3 represents a lower alkoxy group; R.sup.4, R.sup.5, and R.sup.6, which may be the same or different, each represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, a phenyl lower alkyl group, or a phenyl group; and A represents a lower alkylene group; said R.sup.4 and A, said R.sup.5 and A, said R.sup.4 and R.sup.5, or said R.sup.5 and R.sup.

Abstract: A process for producing 2-aminomethyl-1-ethylpyrrolidine by the electrolytic reduction of 1-ethyl-2-nitromethylenepyrrolidine.

Abstract: Novel 1-substituted-1, 4-dihydropyridine derivatives, particularly diethyl 1-ethoxymethyl-4-(3-nitrophenyl)-2, 6-dimethyl-1, 4-dihydropyridine-3,5-dicarboxylate are provided. The novel derivatives have cerebral vascular dilator activity with low toxicity.

Abstract: Novel .alpha.-aminomethylbenzyl alcohol derivatives, particularly .alpha.-aminoethyl-3-substituted amino-4-hydroxybenzyl alcohol derivatives. The compounds of this invention are useful as bronchodilating agents.

Abstract: There are provided novel 1,4-dihydropyridine derivatives, particularly 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-.beta.-(N-benzyl-N-methylamino)ethyl ester and 5-methyl ester. The 1,4-dihydropyridine derivatives are characterized by cerebral vascular dilator activity.

Abstract: A process of preparing a .DELTA..sup.3 -cephalosporanic acid ester derivative which comrises reacting a cephalosporanic acid sulfoxide ester derivative with thionyl halide or a phosphorous halide.The compounds prepared by the process of this invention are useful as intermediate compounds for preparing cephalosporin antibiotics and the compounds themselves are also potential antibacterials.

Abstract: The oxofuryl ester derivatives of 6-(.alpha.-amino-phenylacetamido)penicillanic acid, 7-(.alpha.-aminophenylacetamido)-cephalosporanic acid, or 7-(.alpha. -aminophenylacetamide)desacetoxycephalosporanic acid represented by the general formula ##SPC1##Wherein A represents ##SPC2##Wherein R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom or a lower alkyl group, said R.sup.1 and R.sup.2 may form together a 1,3-butadienylene group, R.sup.3 represents a hydrogen atom or an acetoxy group, andMeans a single bond or a double bond, and acid addition salts of them. When those compounds are orally administered, they are readily absorbed by the intestines and show antibacterial activity by splitting their ester bonds. The rate of absorption of the compounds by the intestines are higher and the toxic property of them is less than those of known compounds similar to the above compounds.

Abstract: A process for the preparation of cephalosporanic acid derivatives represented by the formula ##SPC1##Wherein R.sub.1 and R.sub.2, which may be the same or different, each represents a univalent group other than a hydrogen atom, said R.sub.1 and R.sub.2 may be combined to form a divalent group and A represents a divalent group represented by the formulae ##SPC2##Wherein R.sub.3 represents a hydrogen atom or a group which does not contribute to the reaction, which comprises heating a penicillin sulfoxide derivative represented by the formula ##SPC3##Wherein R.sub.1, R.sub.2 and R.sub.3 are as defined above.The cephalosporanic acid derivatives prepared by the process of this invention are useful as a starting material for the preparation of antibacterials.