Abstract: A compound represented by formula (2) or pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or the like; R2 represents a methoxy group or the like; R3 represents a hydrogen atom or the like; R4 represents an optionally substituted C1-6 alkyl group or the like; m represents 0, 1, or 2; n represents 0, 1, 2, or 3; L1 represents —NH—C(?O)—, —C(?O)—NH—, or the like; L2 represents a single bond or the like; X represents optionally substituted phenyl or the like; Y represents optionally substituted phenyl or the like; and X and Y are bonded at a carbon atom on each ring.

Abstract: The present invention provides an epoxy resin composition including an epoxy resin represented by the following formula (1) and an epoxy resin represented by the following formula (2):

Abstract: The present invention provides an epoxy resin composition including an epoxy resin represented by the following formula (1) and an epoxy resin represented by the following formula (2):

Abstract: An engine with an exhaust treatment device (2) wherein a rotation moment of a side support stay (12) is generated by a load of a side portion (50) received by side support stay fastening tool (13) via an edge portion (21) of a cutout groove (20). As a result, a load of the side portion (50) of the exhaust treatment device (2) can be supported by the side support stay (12). A one-side temporary mount portions (22) is provided in a one-side support stay (10). The one-side support stay (10) can be temporarily mounted on the one-side temporary mount portions (22).

Abstract: An engine with an exhaust treatment device (2) wherein a rotation moment of a side support stay (12) is generated by a load of a side portion (50) received by side support stay fastening tool (13) via an edge portion (21) of a cutout groove (20). As a result, a load of the side portion (50) of the exhaust treatment device (2) can be supported by the side support stay (12). A one-side temporary mount portions (22) is provided in a one-side support stay (10). The one-side support stay (10) can be temporarily mounted on the one-side temporary mount portions (22).

Abstract: The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein R1a is halogen, etc.; R1m is H, etc.; G1 is —N(R1b)—, etc.; G2 is —CO—, etc.; G3 is —C(R1c)(R1d)—, etc.; G4 is oxygen, etc.; R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are independently the same or different, H, etc.; R3 is H, optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c and R3d are independently the same or different, and a group: -A-B (said A is single bond, etc., and said B is H, etc.), etc.; and n is 1, etc.

Abstract: The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein R1a is halogen, etc.; R1m is H, etc.; G1 is —N(R1b)—, etc.; G2 is —CO—, etc.; G3 is —C(R1c)(R1d)—, etc.; G4 is oxygen, etc.; R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are independently the same or different, H, etc.; R3 is H, optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c and R3d are independently the same or different, and a group: -A-B (said A is single bond, etc., and said B is H, etc.), etc.; and n is 1, etc.

Abstract: Disclosed is a compound represented by the formula (1) below, a prodrug thereof or a pharmaceutically acceptable salt of either, which is useful as a therapeutic, preventive or ameliorating agent for diabetes and the like. (In the formula, R3 represents an optionally substituted carbamoyl group or the like; X represents a hydroxyl group or the like; W1 and W2 independently represent a single bond or methylene; R7 and R8 independently represent a hydrogen atom, an optionally substituted alkyl group or the like; and Ar represents an optionally substituted aryl group or the like.

Abstract: The blow-by gas that has flowed from a front-stage breather-chamber inlet (33) into a front-stage breather chamber (28) floats up around a preliminary valve-seat peripheral wall (22) and a preliminary breather-passage peripheral wall (24) and flows from a breather-chamber inlet (21) into a breather chamber (3). When a breather-chamber peripheral wall (12) is removed from a breather-chamber attaching seat (11), a diaphragm valve (16) is attached to the breather-chamber attaching seat (11) and has a valve face (18) seated on a preliminary valve seat (23), and a plug (27) is taken out of a preliminary breather outlet (25), from which a breather pipe (5) is led out, thereby enabling the front-stage breather chamber (28) to be used for a single-stage breather chamber provided with the diaphragm valve (16).

Abstract: Disclosed is a compound represented by the formula (1) below, a prodrug thereof or a pharmaceutically acceptable salt of either, which is useful as a therapeutic, preventive or ameliorating agent for diabetes and the like. (In the formula, R3 represents an optionally substituted carbamoyl group or the like; X represents a hydroxyl group or the like; W1 and W2 independently represent a single bond or methylene; R7 and R8 independently represent a hydrogen atom, an optionally substituted alkyl group or the like; and Ar represents an optionally substituted aryl group or the like.

Abstract: The sealing apparatus comprises (a) a heat seal jaw, (b) a heat seal bar having two heaters arranged in parallel, being provided in a front edge of said heat seal jaw and having a working surface, (c) a counter jaw disposed oppositely to the heat seal jaw, (d) a counter rail provided to said counter jaw and having the working surface, (e) a drive means for advancing/retracting the heat seal jaw and counter jaw relatively, (f) a heating means for actuating the heaters while clamping a packaging material by the working surface of the heat seal bar and the working of the counter rail and, (g) a cutter section comprising of a cutter disposed at the position between the two heaters and a resilient counter cutter, and is characterized in that the counter cutter is held by a holding section provided on the working surface of the heat seal bar or the counter rail and projecting from the holding working surface. The seal apparatus can improve hygiene and the flap formation of the packaging container.

Abstract: An engine comprises a crank case (1) provided with a lower opening portion (2), which is covered with an oil pan (3) from below, and with a pair of left and right oil passages which extends in a front and rear direction along left and right lateral walls (5) and (6). In this engine, the crank case (1) has the left and right lateral walls (5) and (6) provided with left and right ribs (12) and (13) extending in the front and rear direction. These left and right ribs (12) and (13) are raised inwards from the left and right lateral walls (5) and (6) of the crank case (1). In order to provide left and right oil passages (7) and (8) in these left and right ribs (12) and (13), these ribs (12) and (13) are positioned at the lower opening portion (2) of the crank case (1).

Abstract: An engine comprises a crank case (1) provided with a lower opening portion (2), which is covered with an oil pan (3) from below, and with a pair of left and right oil passages which extends in a front and rear direction along left and right lateral walls (5) and (6). In this engine, the crank case (1) has the left and right lateral walls (5) and (6) provided with left and right ribs (12) and (13) extending in the front and rear direction. These left and right ribs (12) and (13) are raised inwards from the left and right lateral walls (5) and (6) of the crank case (1). In order to provide left and right oil passages (7) and (8) in these left and right ribs (12) and (13), these ribs (12) and (13) are positioned at the lower opening portion (2) of the crank case (1).

Abstract: A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

Abstract: The sealing apparatus comprises (a) a heat seal jaw, (b) a heat seal bar having two heaters arranged in parallel, being provided in a front edge of said heat seal jaw and having a working surface, (c) a counter jaw disposed oppositely to the heat seal jaw, (d) a counter rail provided to said counter jaw and having the working surface, (e) a drive means for advancing/retracting the heat seal jaw and counter jaw relatively, (f) a heating means for actuating the heaters while clamping a packaging material by the working surface of the heat seal bar and the working of the counter rail and, (g) a cutter section comprising of a cutter disposed at the position between the two heaters and a resilient counter cutter, and is characterized in that the counter cutter is held by a holding section provided on the working surface of the heat seal bar or the counter rail and projecting from the holding working surface. The seal apparatus can improve hygiene and the flap formation of the packaging container.

Abstract: Therapeutic agents for erectile dysfunction containing as the active ingredient prostaglandin derivatives of formula (I) (wherein, R1 is ethyl or n-2-propenyl.), esters thereof, nontoxic salts thereof, or cyclodextrin clathrate compounds thereof. The compounds of the formula (I) are useful for the treatment of erectile dysfunction.

Abstract: An object is to provide a preforming apparatus allowing smooth travel of a packaging material (11). The preforming apparatus includes first to fourth guides (34 to 37) for forming a web-like packaging material (11) into a tubular packaging material (11); a longitudinal sealing device (41) for longitudinally sealing the tubular packaging material (11); a drive unit; and a tube guide device (38) disposed in such a manner as to surround the tubular packaging material (11), and guiding the tubular packaging material (11) while being driven by means of the drive unit. Activation of the drive unit causes the tube guide device (38) to guide and feed the packaging material (11), thereby preventing the tube guide device (38) from resisting travel of the packaging material (11). Thus, the tube guide device (38) does not yield a braking effect, thereby allowing smooth travel of the packaging material (11).

Abstract: A novel pyrrole derivative represented by the following formula (1) and a salt thereof: 1

Abstract: Therapeutic agents for erectile dysfunction containing as the active ingredient prostaglandin derivatives of formula (I) 1

Abstract: The conductor pattern of a magnetic head coil includes a spiral coil pattern to which a current can be supplied to flow around the magnetic field generation center, and a conductor pattern which is formed outside the coil pattern and cannot receive a current so as to flow around the magnetic field generation center. Letting S be the distance from the outer edge of the outermost periphery of the coil pattern, and P be the pitch, a conductor occupation ratio R of a conductor pattern formed outside the coil pattern simultaneously satisfies inequalities 1 to 3, and the conductor pattern does not form any closed loop surrounding the coil pattern in a first region A1 given by inequality 1: Inequality 1: 0≦R≦0.3 in the first region A1 where 0≦S≦1.5P Inequality 2: 0≦R≦0.8 in a second region A2 where 1.5P<S≦6.0P Inequality 3: 0.3<R≦1 in a third region A3 where 6.