Patents by Inventor Kristian Karlshoej

Kristian Karlshoej has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of fatty alcohols from engineered microorganisms
    Patent number: 9714437
    Abstract: The invention generally relates to the production of a fatty alcohol composition from recombinant microbial cells. The fatty alcohols are produced by expressing a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase (“FAR”); a gene encoding a heterologous thioesterase (“TE”) gene and a gene encoding an acyl-CoA synthetase (“ACS”).
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: July 25, 2017
    Assignee: Codexis, Inc.
    Inventors: Kaman Chan, Fernando Valle, Yoram Barak, Louis Clark, Kristian Karlshoej, Jonathan Vroom, Jovana Nazor, Claus M Krebber, Kenneth Mitchell
  • Production of fatty alcohols from engineered microorganisms
    Patent number: 9650655
    Abstract: Recombinant microorganisms are provided which have been engineered to produce fatty alcohols. Also provided are recombinant microorganisms which comprise a heterologous polynucleotide encoding a fatty alcohol reductase enzyme and an introduced polynucleotide encoding a ?-ketoacyl acyl carrier protein synthase.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: May 16, 2017
    Assignee: Codexis, Inc.
    Inventors: Jonathan Vroom, Svetlana Balatskaya, Yoram Barak, Louis Clark, Trish Choudhary, Kristian Karlshoej, Fernando Valle, Kaman Chan
  • Production of saturated fatty alcohols from engineered microorganisms
    Patent number: 9447436
    Abstract: Recombinant bacterial microorganisms are provided which comprise heterologous fatty acyl reductases (“FAR”) polypeptides wherein said microorganisms have been engineered to produce increased amounts of saturated fatty alcohols and methods of making saturated fatty alcohols using the recombinant bacterial microorganisms.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: September 20, 2016
    Assignee: Codexis, Inc.
    Inventors: Fernando Valle, Svetlana Balatskaya, Yoram Barak, Louis Clark, Kristian Karlshoej, Patricia Choudhary, Catherine Cho, Kaman Chan, Jonathan Vroom
  • PRODUCTION OF FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS
    Publication number: 20160244787
    Abstract: The invention generally relates to the production of a fatty alcohol composition from recombinant microbial cells. The fatty alcohols are produced by expressing a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase (“FAR”); a gene encoding a heterologous thioesterase (“TE”) gene and a gene encoding an acyl-CoA synthetase (“ACS”).
    Type: Application
    Filed: May 9, 2016
    Publication date: August 25, 2016
    Inventors: Kaman Chan, Fernando Valle, Yoram Barak, Louis Clark, Kristian Karlshoej, Jonathan Vroom, Jovana Nazor, Claus M Krebber, Kenneth Mitchell
  • Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
    Patent number: 9163221
    Abstract: The present disclosure provides methods useful for producing fatty alcohol compositions from recombinant host cells. The disclosure further provides variant fatty acyl-CoA reductase (FAR) enzymes, polynucleotides encoding the variant FAR enzymes, and vectors and host cells comprising the same.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: October 20, 2015
    Assignee: CODEXIS, INC.
    Inventors: Behnaz Behrouzian, Louis Clark, Yihui Zhu, Michael Clay, Kristian Karlshoej
  • PRODUCTION OF FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS
    Publication number: 20150176040
    Abstract: Recombinant microorganisms are provided which have been engineered to produce fatty alcohols. Also provided are recombinant microorganisms which comprise a heterologous polynucleotide encoding a fatty alcohol reductase enzyme and an introduced polynucleotide encoding a ?-ketoacyl acyl carrier protein synthase.
    Type: Application
    Filed: July 19, 2013
    Publication date: June 25, 2015
    Applicant: Codexis, Inc.
    Inventors: Jonathan Vroom, Svetlana Balatskaya, Yoram Barak, Louis Clark, Trish Choudhary, Kristian Karlshoej, Fernando Valle, Kaman Chan
  • PRODUCTION OF FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS
    Publication number: 20150133698
    Abstract: The invention generally relates to the production of a fatty alcohol composition from recombinant microbial cells. The fatty alcohols are produced by expressing a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase (“FAR”); a gene encoding a heterologous thioesterase (“TE”) gene and a gene encoding an acyl-CoA synthetase (“ACS”).
    Type: Application
    Filed: April 19, 2013
    Publication date: May 14, 2015
    Inventors: Kaman Chan, Fernando Valle, Yoram Barak, Louis Clark, Kristian Karlshoej
  • FATTY ALCOHOL FORMING ACYL REDUCTASE (FAR) VARIANTS AND METHODS OF USE
    Publication number: 20140357727
    Abstract: The present disclosure provides methods useful for producing fatty alcohol compositions from recombinant host cells. The disclosure further provides fatty acyl-CoA reductase (FAR) variant enzymes, polynucleotides encoding the FAR variant enzymes, and vectors and host cells comprising polynucleotides encoding the FAR variant enzymes.
    Type: Application
    Filed: December 13, 2012
    Publication date: December 4, 2014
    Inventors: Louis A. Clark, Kristian Karlshoej, Patricia Choudhary
  • PRODUCTION OF SATURATED FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS
    Publication number: 20140336423
    Abstract: Recombinant bacterial microorganisms are provided which comprise heterologous fatty acyl reductases (“FAR”) polypeptides wherein said microorganisms have been engineered to produce increased amounts of saturated fatty alcohols and methods of making saturated fatty alcohols using the recombinant bacterial microorganisms.
    Type: Application
    Filed: December 13, 2012
    Publication date: November 13, 2014
    Inventors: Fernando Valle, Svetlana Balatskaya, Yoram Barak, Louis Clark, Kristian Karlshoej, Patricia Choudhary, Catherine Cho, Kaman Chan, Jonathan Vroom
  • FATTY ALCOHOL FORMING ACYL REDUCTASES (FARS) AND METHODS OF USE THEREOF
    Publication number: 20140093929
    Abstract: The present disclosure provides methods useful for producing fatty alcohol compositions from recombinant host cells. The disclosure further provides variant fatty acyl-CoA reductase (FAR) enzymes, polynucleotides encoding the variant FAR enzymes, and vectors and host cells comprising the same.
    Type: Application
    Filed: September 27, 2013
    Publication date: April 3, 2014
    Inventors: Behnaz Behrouzian, Louis Clark, Yihui Zhu, Michael Clay, Kristian Karlshoej
  • Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
    Patent number: 8574878
    Abstract: The present disclosure provides methods useful for producing fatty alcohol compositions from recombinant host cells. The disclosure further provides variant fatty acyl-CoA reductase (FAR) enzymes, polynucleotides encoding the variant FAR enzymes, and vectors and host cells comprising the same.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: November 5, 2013
    Inventors: Behnaz Behrouzian, Louis Clark, Yihui Zhu, Michael Clay, Kristian Karlshoej
  • FATTY ALCOHOL FORMING ACYL REDUCTASES (FARS) AND METHODS OF USE THEREOF
    Publication number: 20120009640
    Abstract: The present disclosure provides methods useful for producing fatty alcohol compositions from recombinant host cells. The disclosure further provides variant fatty acyl-CoA reductase (FAR) enzymes, polynucleotides encoding the variant FAR enzymes, and vectors and host cells comprising the same.
    Type: Application
    Filed: June 28, 2011
    Publication date: January 12, 2012
    Applicant: Codexis, Inc.
    Inventors: Behnaz Behrouzian, Louis Clark, Yihui Zhu, Michael Clay, Kristian Karlshoej