Abstract: A flexible endoscopic clip applier includes a flexible coil with a manual actuator coupled to one end and a jaw assembly coupled to the other end. A store of clips is arranged adjacent to the jaw assembly and a clip pusher is arranged adjacent to the store of clips. The actuator includes a lever for opening and closing the jaws, a knob for rotating the jaw assembly, and a crank for dispensing clips. The knob and the lever are coupled to a single control member which extends through the coil to a joiner where it is joined to a pair of pull wires coupled to the jaws. The crank is coupled to a second control member which is threaded along a distal portion. The threaded portion engages a threaded member near the pusher and is coupled to the pusher such that rotation of the threaded control member by the crank causes the pusher to be moved distally.

Abstract: A surgical instrument is adapted for applying a plurality of surgical fasteners to body tissue. The surgical instrument includes an anvil and a cartridge housing containing a plurality of surgical fasteners. The cartridge housing and anvil are relatively movable between a first spaced apart position and a second closed position. A firing mechanism is associated with the cartridge housing for ejecting the surgical fasteners from the cartridge housing to be driven against the anvil. A lockout mechanism interacts with the cartridge housing for activation and deactivation; the lockout mechanism preventing movement of the cartridge housing to its second closed position but permitting relative reapproximation movement of the cartridge housing and anvil, whereby reapproximation provides an indicator that the instrument is not malfunctioning.