Abstract: A deformable container that is suitable for dispensing dishwasher machine cleaner in an automatic dishwasher. The container defines an interior volume for a fluid, and includes an outlet fluidly connected to the interior volume. A portion of the container is deformable upon reaching a predetermined temperature to reduce the size of the interior volume for forcing the fluid out from the container via the outlet. A seal at the outlet is openable by the fluid forced from the interior volume when the size of the interior volume is reduced to control the escape of fluid from the container.

Abstract: Process for preparation of MK-7 type of vitamin K2 is characterized by attaching hexaprenyl chain of “all-trans” configuration to monoprenyl derivative of menadiol following “1+6” synthetic strategy. According to the invention, a-sulfonyl carbanion generated in situ from the protected monoprenyl menadiol of the formula (II), wherein R1 represents C1-3-alkyl group, is reacted with hexaprenyl halide of the formula (VII), wherein X represents halogen atom, preferably bromine, both Z? and Z? represent H or one of Z? and Z? represents H and the other represents phenylsulfonyl group —SO2Ph in the alkylation reaction. The hexaprenyl halide of formula (VII) is obtained by coupling two triprenyl units in alkylation reaction, with or without separation of the intermediates.

Abstract: Process for preparation of MK-7 type of vitamin K2 is characterized by attaching hexaprenyl chain of “all-trans” configuration to monoprenyl derivative of menadiol following “1+6” synthetic strategy. According to the invention, a-sulfonyl carbanion generated in situ from the protected monoprenyl menadiol of the formula (II), wherein R1 represents C1-3-alkyl group, is reacted with hexaprenyl halide of the formula (VII), wherein X represents halogen atom, preferably bromine, both Z? and Z? represent H or one of Z? and Z? represents H and the other represents phenylsulfonyl group —SO2Ph in the alkylation reaction. The hexaprenyl halide of formula (VII) is obtained by coupling two triprenyl units in alkylation reaction, with or without separation of the intermediates.

Abstract: The present invention discloses the synthone of Formula (I), wherein R1 and R2 are the same or different and represent independently hydrogen atom or hydroxyl protecting group, and its use for preparation of 19-nor vitamin D derivatives of general Formula (IV), wherein represents single or double bond, p represents an integer 0 to 3, R1 and R2 represent independently hydrogen atom or hydroxyl protecting group, R3 represents hydrogen atom, CH3 or hydroxyl group, R4, R5 and R6 represent independently hydrogen atom, C1-C3-alkyl or hydroxyl group or two of R4, R5 and R6 substituents altogether form cyclopropyl group, in particular for preparation of paricalcitol.

Abstract: A compound indenter for a wire connector pin, the pin having an axial length and an opening at an end thereof for receiving a wire having an exposed portion and an insulation covered portion, the opening being sized to receive both the exposed portion and a length of the insulation covered portion comprises a first indenter having a plurality of indenting elements for engaging the pin in an axial location overlaying the exposed portion of the wire inserted in the pin and a second indenter having a plurality of indenting elements for engaging the pin in an axial location overlaying the insulation covered portion of the wire inserted in the pin. The apparatus advances the indenting elements of each of the first and second indenters generally concurrently for compressing respective sections of the pin into engagement with the exposed wire portion and the insulation covered portions of the wire.