Abstract: The present invention relates to a safety mechanism for multi-shot air guns having a main housing, a barrel, a launch port located at the barrel of the main housing and adapted for air pressure connection to an aligned nozzle and having a pressurization mechanism and a release for releasing pressure from the launch port to an aligned nozzle and having a multi-shot projectile magazine capable of having one nozzle aligned with the launch port and being advanceable to provide sequential alignments of nozzles for firings of a plurality of projectiles. Each nozzle includes an impediment member contained therein. The safety mechanism includes one or more valves connected to either the launch port or each of the nozzles, to prevent flow of pressurized air into the nozzles when closed and to allow flow of pressurized air when opened; a biasing device for biasing the valve to a closed position; an opening device movably located within the nozzle.