Patents by Inventor Kuang Ning Chang

Kuang Ning Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7682826
    Abstract: Provided herein are human embryonic stem cells and their method of culturing. In one embodiment, the human embryonic stem cells are maintained in an environment containing an extracellular matrix isolated from feeder cells and a conditioned medium pre-conditioned by the feeder cells; the feeder cells are pre-inactivated by either gamma ray radiation or by mitomycin C treatment. The cultured human embryonic stem cells remain substantially undifferentiated and maintain their pluripotency to differentiate into three germ layer cells.
    Type: Grant
    Filed: September 23, 2005
    Date of Patent: March 23, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Mei Ju Yang, Kuang Ning Chang, Lih Tao Hsu, Jun Jae Huang, Wann Hsin Chen, Chao Ying Kuo
  • Patent number: 7255705
    Abstract: A device for dissecting an object, such as a cell colony includes a handle and an incision knife module that can dissociate the colony into several colony pieces. In accordance with features of the invention, users can use this dissecting device to cut an object into several pieces quickly and smoothly at a time.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: August 14, 2007
    Assignee: Industrial Technology Research Institute
    Inventors: Lih Tao Hsu, Wannhsin Chen, Kuang Ning Chang, Mei Ju Yang, Jinn Fa Wu, Yeou Bin Guu
  • Publication number: 20060030040
    Abstract: Provided herein are human embryonic stem cells and their method of culturing. In one embodiment, the human embryonic stem cells are maintained in an environment containing an extracellular matrix isolated from feeder cells and a conditioned medium pre-conditioned by the feeder cells; the feeder cells are pre-inactivated by either gamma ray radiation or by mitomycin C treatment. The cultured human embryonic stem cells remain substantially undifferentiated and maintain their pluripotency to differentiate into three germ layer cells.
    Type: Application
    Filed: September 23, 2005
    Publication date: February 9, 2006
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Mei-Ju Yang, Kuang-Ning Chang, Lih-Tao Hsu, Jun-Jae Huang, Wann-Hsin Chen, Chao-Ying Kuo
  • Publication number: 20050124063
    Abstract: The present invention discloses an improved culture system for proliferative and undifferentiated growth of human embryonic stem cells, comprising an extracellular matrix prepared from feeder cells and a conditioned medium preconditioned by feeder cells. This invention also relates to a culture method utilizing the foregoing culture system.
    Type: Application
    Filed: May 6, 2004
    Publication date: June 9, 2005
    Applicant: Industrial Technology Research
    Inventors: Mei-Ju Yang, Kuang-Ning Chang, Lih-Tao Hsu, Jun-Jae Huang, Wann-Hsin Chen, Chao-Ying Kuo
  • Publication number: 20040138686
    Abstract: A device for dissecting an object, such as a cell colony includes a handle and an incision knife module that can dissociate the colony into several colony pieces. In accordance with features of the invention, users can use this dissecting device to cut an object into several pieces quickly and smoothly at a time.
    Type: Application
    Filed: December 24, 2003
    Publication date: July 15, 2004
    Applicant: Industrial Technology Research Institute
    Inventors: Lin-Tao Hsu, Wannhsin Chen, Kuang-Ning Chang, Mei-Ju Yang, Jinn-Fa Wu, Yeou-Bin Guu