Patents by Inventor Kuniko K. Kretzmer

Kuniko K. Kretzmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for isolating tissue factor inhibitor
    Patent number: 7060805
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: June 13, 2006
    Assignees: Pfizer Inc., Washington University
    Inventors: Tze Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • DNA clone of human tissue factor inhibitor
    Publication number: 20040265981
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 30, 2004
    Applicant: G. D. SEARLE & CO.
    Inventors: Tze Chein Wun, Kuniko K. Kretzmer, George J. Broze
  • Nucleic acids encoding human tissue factor inhibitor
    Patent number: 6806360
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: October 19, 2004
    Assignee: G.D. Searle & Co.
    Inventors: Tze Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • DNA clone of human tissue factor inhibitor
    Publication number: 20030166194
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Application
    Filed: March 4, 2003
    Publication date: September 4, 2003
    Applicant: G. D. SEARLE & CO.
    Inventors: Tze Chein Wun, Kuniko K. Kretzmer, George J. Broze
  • Methods for detecting human tissue factor inhibitor
    Patent number: 6534276
    Abstract: Molecules, such as antibodies, with binding specificity for Tissue factor Inhibitor (TFI) or for polypeptides comprising one or more Kunitz domains of TFI can be used in methods to detect TFI or polypeptides containing a Kunitz domain of TFI in biological fluids. Either direct or indirect detection methods can be carried out.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: March 18, 2003
    Assignee: G. D. Searle & Company
    Inventors: Tze Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • Antibodies to tissue factor inhibitor
    Patent number: 6171587
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined. Antibodies having a binding region specific to human tissue factor inhibitor are disclosed.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: January 9, 2001
    Assignee: G. D. Searle and Company
    Inventors: Tze Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • Human tissue factor inhibitor
    Patent number: 5849875
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 15, 1998
    Assignee: G. D. Searle & Co.
    Inventors: Tze-Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • DNA clone of human tissue factor inhibitor
    Patent number: 5773251
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 30, 1998
    Assignee: G.D. Searle & Co.
    Inventors: Tze-Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • Human tissue factor inhibitor
    Patent number: 5466783
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Grant
    Filed: July 15, 1993
    Date of Patent: November 14, 1995
    Assignees: Monsanto Company, Washington University
    Inventors: Tze-Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.
  • DNA clone of human tissue factor inhibitor
    Patent number: 4966852
    Abstract: A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined.
    Type: Grant
    Filed: November 23, 1987
    Date of Patent: October 30, 1990
    Assignees: Monsanto Company, Washington University
    Inventors: Tze-Chein Wun, Kuniko K. Kretzmer, George J. Broze, Jr.