Abstract: A method of producing a product inorganic compound including: immersing a raw material inorganic compound having a volume of 10?13 m3 or more in an electrolyte aqueous solution or an electrolyte suspension; exchanging anions in the raw material inorganic compound with anions in the electrolyte aqueous solution or the electrolyte suspension; cations in the raw material inorganic compound are exchanged with cations in the electrolyte aqueous solution or the electrolyte suspension; or including a component (that excludes water, hydrogen, and oxygen) in the electrolyte aqueous solution or the electrolyte suspension not included in the raw material inorganic compound in the raw material inorganic compound; and obtaining a product inorganic compound having a volume of 10?13 m3 or more from the raw material inorganic compound.

Abstract: A medical honeycomb structure lacking at least a portion of an outer peripheral side wall of a honeycomb structure that includes a plurality of through-holes extending in one direction, wherein sites lacking the outer peripheral side wall have a plurality of grooves, and have a plurality of planes including distant surfaces of groove side walls flanked by the grooves.

Abstract: A medical polymer material in which a phosphate group having a C—O—P chemical bond including elemental C in a main chain of a structural formula is present on a surface of a polymer material substantially free of phosphate and hydroxy groups except for ends in the structural formula.

Abstract: Provided is a medical calcium carbonate composition that highly satisfies 1) tissue affinity, 2) in vivo resorbability, 3) reactivity, and 4) mechanical strength required for medical materials to be implanted in vivo, a medical calcium phosphate composition, a medical carbonate apatite composition, a medical calcium hydroxide porous structure, a medical calcium sulfate setting granules, and a bone defect regeneration kit related to the medical calcium carbonate composition, and methods for producing these. The medical composition calcium carbonate that highly satisfies the above described elements, and related medical compositions can be produced by controlling the polymorph or structure of calcium carbonate.

Abstract: A medical use honeycomb structure having a plurality of through-holes extending in one direction, wherein an outer peripheral section of the medical use honeycomb structure has a through-hole groove formed by incomplete side walls of the through-hole, and a through-hole inlet adjacent to the through-hole groove.

Abstract: A medical use honeycomb structure having a plurality of through-holes extending in one direction, wherein an outer peripheral section of the medical use honeycomb structure has a through-hole groove formed by incomplete side walls of the through-hole, and a through-hole inlet adjacent to the through-hole groove.

Abstract: To provide a method for producing a calcium carbonate block for medical use which is useful as a bone substitute or a bone substitute raw material needed in medical care, which is a method for producing a calcium carbonate block that satisfies the following desired properties: 1) the calcium carbonate block has excellent mechanical strength; 2) the calcium carbonate block can be produced by a simplified production method; 3) the calcium carbonate block contains no impurity; and 4) the calcium carbonate block has high reactivity. A method for producing a calcium carbonate block, comprising a step of shaping a water-containing calcium hydroxide block and a carbonation step of immersing the calcium hydroxide block in a carbonate ion-containing aqueous solution.

Abstract: A medical polymer material in which a phosphate group having a C—O—P chemical bond including elemental C in a main chain of a structural formula is present on a surface of a polymer material substantially free of phosphate and hydroxy groups except for ends in the structural formula.

Abstract: The present invention provides: a method for producing a shaped product comprising octacalcium phosphate and having a volume of 2.0 mm3 or more, comprising immersing a precursor ceramic composition containing at least one of Ca and PO4 in composition, having a solubility in H2O higher than that of octacalcium phosphate, and having a volume greater than 2.0 mm3, in a solution containing a component which is not contained in the precursor ceramic composition, among the components Ca, PO4 and H2O, which are components of octacalcium phosphate to allow the precursor ceramic composition to react, thereby converting at least a part of the precursor ceramic composition into octacalcium phosphate; and the like.

Abstract: A method of producing a product inorganic compound including: immersing a raw material inorganic compound having a volume of 10?13 m3 or more in an electrolyte aqueous solution or an electrolyte suspension; exchanging anions in the raw material inorganic compound with anions in the electrolyte aqueous solution or the electrolyte suspension; cations in the raw material inorganic compound are exchanged with cations in the electrolyte aqueous solution or the electrolyte suspension; or including a component (that excludes water, hydrogen, and oxygen) in the electrolyte aqueous solution or the electrolyte suspension not included in the raw material inorganic compound in the raw material inorganic compound; and obtaining a product inorganic compound having a volume of 10?13 m3 or more from the raw material inorganic compound.

Abstract: The present invention provides: a method for producing a shaped product comprising octacalcium phosphate and having a volume of 2.0 mm3 or more, comprising immersing a precursor ceramic composition containing at least one of Ca and PO4 in composition, having a solubility in H2O higher than that of octacalcium phosphate, and having a volume greater than 2.0 mm3, in a solution containing a component which is not contained in the precursor ceramic composition, among the components Ca, PO4 and H2O, which are components of octacalcium phosphate to allow the precursor ceramic composition to react, thereby converting at least a part of the precursor ceramic composition into octacalcium phosphate; and the like.

Abstract: To provide a method for producing a calcium carbonate block for medical use which is useful as a bone substitute or a bone substitute raw material needed in medical care, which is a method for producing a calcium carbonate block that satisfies the following desired properties: 1) the calcium carbonate block has excellent mechanical strength; 2) the calcium carbonate block can be produced by a simplified production method; 3) the calcium carbonate block contains no impurity; and 4) the calcium carbonate block has high reactivity. A method for producing a calcium carbonate block, comprising a step of shaping a water-containing calcium hydroxide block and a carbonation step of immersing the calcium hydroxide block in a carbonate ion-containing aqueous solution.

Abstract: A medical use honeycomb structure having a plurality of through-holes extending in one direction, wherein an outer peripheral section of the medical use honeycomb structure has a through-hole groove formed by incomplete side walls of the through-hole, and a through-hole inlet adjacent to the through-hole groove.

Abstract: An object is to provide a method for manufacturing a calcium carbonate block of no less than 0.1 cm in diameter and thickness, not including any impurities, and able to be employed as a raw material of an artificial bone that requires biosafety: the method includes: (a) shaping a calcium hydroxide block; (b) being exposed to carbon dioxide; and (c) immersing in a carbonate ion containing solution.

Abstract: A method of producing a product inorganic compound including: immersing a raw material inorganic compound having a volume of 10?13 m3 or more in an electrolyte aqueous solution or an electrolyte suspension; exchanging anions in the raw material inorganic compound with anions in the electrolyte aqueous solution or the electrolyte suspension; cations in the raw material inorganic compound are exchanged with cations in the electrolyte aqueous solution or the electrolyte suspension; or including a component (that excludes water, hydrogen, and oxygen) in the electrolyte aqueous solution or the electrolyte suspension not included in the raw material inorganic compound in the raw material inorganic compound; and obtaining a product inorganic compound having a volume of 10?13 m3 or more from the raw material inorganic compound.

Abstract: An object is to provide a method for manufacturing a calcium carbonate block of no less than 0.1 cm in diameter and thickness, not including any impurities, and able to be employed as a raw material of an artificial bone that requires biosafety: the method includes: (a) shaping a calcium hydroxide block; (b) being exposed to carbon dioxide; and (c) immersing in a carbonate ion containing solution.

Abstract: A work procedure display method of displaying a work procedure on a work object by a computer displaying a moving image, the method comprising: (a) displaying an entire image of the work object so that start of work is recognizable by a worker; (b) increasing display magnification of the work object so that a working target site of the work object is displayed in an enlarged manner; (c) displaying a moving image showing content of work; (d) displaying an image for the worker to recognize end of work; and (e) accepting instruction to complete the work; wherein steps (a) to (d) are repeatedly executed until instruction to complete the work is accepted, is disclosed. A work procedure display method and system and computer program of the same is also disclosed.

Abstract: There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.

Abstract: The present invention relates to a medical tissue-binding material, especially a soft tissue-binding material capable of attaching to a soft biological tissue such as a bone reconstruction material or a transdermal terminal, and a method for preparation thereof. In particular, the present invention relates to a medical tissue-binding material which comprises a base material having calcium binding onto the surface, provided that the base material is not titanium or titanium alloy. Also, the present invention relates to a method for preparing a medical tissue-binding material which comprises soaking a base material into a calcium ion containing solution. Introduction of at least one group selected from the group consisting of hydroxyl, carboxyl, sulfonate, amino, silanol and phosphate to the surface of the base material is effective for said method.

Abstract: There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.