Patents by Inventor Kyle Kolaja

Kyle Kolaja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagent sets and gene signatures for renal tubule injury
    Patent number: 7588892
    Abstract: The invention discloses reagent sets and gene signatures for predicting onset of renal tubule injury in a subject. The invention also provides a necessary set of 186 genes useful for generating signatures of varying size and performance capable of predicting onset of renal tubule injury. The invention also provides methods, apparatuses and reagents useful for predicting future renal tubule injury based on expression levels of genes in the signatures. In one particular embodiment the invention provides a method for predict whether a compound will induce renal tubule injury using gene expression data from sub-acute treatments.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: September 15, 2009
    Assignee: Entelos, Inc.
    Inventors: Georges Natsoulis, Mark Fielden, Kurt Jarnagin, Kyle Kolaja
  • Reagent sets and gene signatures for renal tubule injury
    Publication number: 20060199205
    Abstract: The invention discloses reagent sets and gene signatures for predicting onset of renal tubule injury in a subject. The invention also provides a necessary set of 186 genes useful for generating signatures of varying size and performance capable of predicting onset of renal tubule injury. The invention also provides methods, apparatuses and reagents useful for predicting future renal tubule injury based on expression levels of genes in the signatures. In one particular embodiment the invention provides a method for predict whether a compound will induce renal tubule injury using gene expression data from sub-acute treatments.
    Type: Application
    Filed: February 17, 2006
    Publication date: September 7, 2006
    Inventors: Georges Natsoulis, Mark Fielden, Kurt Jarnagin, Kyle Kolaja
  • Reagent sets and gene signatures for renal tubule injury
    Publication number: 20060057066
    Abstract: The invention discloses reagent sets and gene signatures for predicting onset of renal tubule injury in a subject. The invention also provides a necessary set of 186 genes useful for generating signatures of varying size and performance capable of predicting onset of renal tubule injury. The invention also provides methods, apparatuses and reagents useful for predicting future renal tubule injury based on expression levels of genes in the signatures. In one particular embodiment the invention provides a method for predict whether a compound will induce renal tubule injury using gene expression data from sub-acute treatments.
    Type: Application
    Filed: July 18, 2005
    Publication date: March 16, 2006
    Inventors: Georges Natsoulis, Mark Fielden, Kurt Jarnagin, Kyle Kolaja