Abstract: The present invention relates to an interdigitated microelectrode biosensor using the reaction between receptors and target biomaterials, the interdigitated microelectrode biosensor comprising: an insulating layer formed so as to cover all of the sensor formation area of a substrate; a first interdigitated microelectrode formed such that a plurality of first protruding electrodes are arranged in a comb shape on the insulating layer of the substrate; a second interdigitated microelectrode, facing the first interdigitated microelectrode and formed such that a plurality of second protruding electrodes are arranged in a comb shape on the insulating layer of the substrate such that the plurality of second protruding electrodes are arranged to respectively interdigitate with the plurality of first protruding electrodes formed at the first interdigitated microelectrode; and a plurality of receptors arranged in the space between the first and second interdigitated microelectrodes, which are arranged to interdigitate

Abstract: A biosensor of the present invention comprises: a first microelectrode and a second microelectrode arranged to intersect in a comb shape on a substrate; and a plurality of receptors fixed in a space between the microelectrodes to specifically react with a target biomaterial. In particular, a micropattern of a conductive material is formed in the space between the microelectrodes. Accordingly, greater electric field intensity can be obtained compared to a biosensor without micropatterns, thereby concentration of the target biomaterial using dielectric electrophoretic forces can be performed more efficiently. In addition, damage to biomolecules can be prevented by lowering the intensity of a voltage for a dielectric electrophoresis phenomenon and the biosensor can be easily commercialized as a health care sensor for diagnosing diseases.

Abstract: The RGO (Reduced Graphene Oxide)-based bio sensor according to the present invention comprises: a source electrode and a drain electrode formed on a substrate; an RGO channel formed between the source electrode and the drain electrode; a PDMS (polydimethylsiloxane) chip supplying a reaction solution to the RGO channel; a passivation layer for sealing in order to prevent the reaction solution supplied through the PDMS chip from touching the source electrode and the drain electrode; and a gate electrode electrically connected to the reaction solution contacted to the RGO by being supplied through the PDMS chip. At this time, the passivation layer is formed with a SU-8 photoresistor, and the gate electrode is directly contacted to the reaction solution to thereby realize a liquid phase driving. The passivation layer is formed with SU-8 to allow supply of reaction solution through PDMS chip to be conveniently and stably realized. The operation is made possible at a gate voltage of ?1.0V˜1.

Abstract: The present invention relates to an interdigitated microelectrode biosensor using the reaction between receptors and target biomaterials, the interdigitated microelectrode biosensor comprising: an insulating layer formed so as to cover all of the sensor formation area of a substrate; a first interdigitated microelectrode formed such that a plurality of first protruding electrodes are arranged in a comb shape on the insulating layer of the substrate; a second interdigitated microelectrode, facing the first interdigitated microelectrode and formed such that a plurality of second protruding electrodes are arranged in a comb shape on the insulating layer of the substrate such that the plurality of second protruding electrodes are arranged to respectively interdigitate with the plurality of first protruding electrodes formed at the first interdigitated microelectrode; and a plurality of receptors arranged in the space between the first and second interdigitated microelectrodes, which are arranged to interdigitate

Abstract: Provided is a protein detection system using a micro-cantilever and based on immune responses, wherein the micro-cantilever shows significantly improved sensitivity to allow detection of a trace amount of biomolecule. To the micro-cantilever, sandwich immunoassay is applied, and the sandwich immunoassay uses a polyclonal antibody or silica nanoparticles having a monoclonal antibody bound thereto, so that variations in the output signals of the cantilever are amplified and the detection sensitivity is significantly improved. The system enables detection of disease specific antigen at several femtomolar levels, and makes it possible to detect a trace amount of protein related to diseases, particularly to cancers, with ease.

Abstract: Disclosed are system and method for measuring a bio-element capable of accurately detecting whether a bio-element such as protein, gene and the like is present in an atmosphere or vapor phase having controlled temperature and humidity thereof and measuring a content of the bio-element. According to an embodiment of the invention, the method comprises steps of preparing a cantilever sensor having a plurality of cantilevers; measuring a basis resonant frequency for the plurality of cantilevers; reacting the cantilevers with a sample including a bio-element; measuring resonant frequencies of the cantilevers after the reaction, in a closed system that is isolated from an exterior environment and temperature and humidity thereof are controlled to a specific state; and calculating variations of the resonant frequencies of the cantilevers before and after the reaction to carry out a quantitative analysis of the bio-element included in the sample.