Abstract: A reversible vein resin needle set for one time use designed not only to make the injection faster and convenient when injecting blood or injectant, but also to protect physicians and nurses from infection of AIDS, etc. caused by the metal needle stained by patient's blood. The device prevents the patient from infection of viruses through the metal needle by protecting the metal needle either in the cylinder of the resin needle set or in the connector, when injecting blood or injectant into the vein of a patient, by connecting the injectant container and one side of the resin needle set by the injectant line linked to the injectant regulator, and by keeping the metal needle in the cylindrical film shield or in the protective cylinder to shut off the outside. The device also protects the metal needle handling personnel from infection of AIDS and other diseases by holding the needle tip either in the cylinder or in the elastic body and in the rubber cap after the use of the metal needle.