Abstract: The present disclosure provides autotaxin (ATX) inhibitor compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for inhibiting ATX. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.

Abstract: Provided is a method performed by a least one computing device for a message service. The method comprises receiving a transmission request for a compound message which is a bundled message comprising a parent message and a plurality of child messages, obtaining permission information for a sender of the compound message, determining whether to allow each of the child messages to be sent based on the permission information and controlling transmission of the compound message based on the determination result.

Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: According to one embodiment of the present disclosure, the head cradle including 5 two head band members fastened to each other is provided, where the head band member includes: a support member extending in one direction; a first fastening part formed at one end portion of the support member and having an insertion hole formed to pass therethrough; a second fastening part formed at the other end portion of the support member; and a strap connection part which is formed at an end portion of the first 0 fastening part or the second fastening part and to which a strap connected to a mask main body is connected, where the support member includes a hole-section on which at least one slit hole having a shape extending at a predetermined angle with respect to the one direction is formed.

Abstract: According to one embodiment of the present disclosure, the head cradle including 5 two head band members fastened to each other is provided, where the head band member includes: a support member extending in one direction; a first fastening part formed at one end portion of the support member and having an insertion hole formed to pass therethrough; a second fastening part formed at the other end portion of the support member; and a strap connection part which is formed at an end portion of the first 0 fastening part or the second fastening part and to which a strap connected to a mask main body is connected, where the support member includes a hole-section on which at least one slit hole having a shape extending at a predetermined angle with respect to the one direction is formed.

Abstract: The present invention relates to an anticancer adjuvant containing, as an active ingredient, protopanaxadiol (PPD) or a compound-K, which are types of panaxadiol ginsenoside compounds, and a pharmaceutical composition for treating cancer containing the anticancer adjuvant and an anticancer agent having mitochondria-mediated anticancer activity. The anticancer adjuvant containing the PPD or compound-K provided in the present invention as an active ingredient damages mitochondria in cancer cells, thereby aiding mitochondria-mediated anticancer activity, and thus can be widely used in safer treatment or alleviation of cancer using anticancer agents that exhibit mitochondria-mediated anticancer activity.

Abstract: The present invention is directed to a method for screening a regulator of mitochondrial fission using a cell treated to a protopanaxadiol (PPD)-type ginsenoside compound, a composition therefor, and a kit comprising the composition. As the use of the method for screening the regulator of mitochondrial fission of the present invention enables effective discovery of a formulation capable of preventing, improving, or treating a mitochondria-related disease, the method will be widely used for the development of a therapeutic agent for the mitochondria-related disease.

Abstract: The present invention relates to an anticancer adjuvant containing, as an active ingredient, protopanaxadiol (PPD) or a compound-K, which are types of panaxadiol ginsenoside compounds, and a pharmaceutical composition for treating cancer containing the anticancer adjuvant and an anticancer agent having mitochondria-mediated anticancer activity. The anticancer adjuvant containing the PPD or compound-K provided in the present invention as an active ingredient damages mitochondria in cancer cells, thereby aiding mitochondria-mediated anticancer activity, and thus can be widely used in safer treatment or alleviation of cancer using anticancer agents that exhibit mitochondria-mediated anticancer activity.

Abstract: The present invention is directed to a method for screening a regulator of mitochondrial fission using a cell treated to a protopanaxadiol (PPD)-type ginsenoside compound, a composition therefor, and a kit comprising the composition. As the use of the method for screening the regulator of mitochondrial fission of the present invention enables effective discovery of a formulation capable of preventing, improving, or treating a mitochondria-related disease, the method will be widely used for the development of a therapeutic agent for the mitochondria-related disease.

Abstract: A apparatus for molding curved glass comprises: a plurality of mold units formed in a chamber for thermomolding and including a lower mold which has one or more cavities such that each of the cavities is injected with glass and an upper mold corresponding to the shape of glass to be processed and arranged on the upper side of the lower mold; and first and second processing apparatuses respectively including an inlet part for the plurality of mold units which are put, a preheating part for increasing the temperature of the glass, a molding part for molding the glass, a cooling part for cooling the molded glass and an outlet part for discharging the cooled glass, wherein the molding part can gradually decrease the increase rate of the heat applied to the plurality of mold units from the inlet part side to the cooling part side.

Abstract: The present invention relates to a blue light-emitting compound for organic polymer EL devices and organic EL devices having superior color purity and light-emitting efficiency by providing a blue light-emitting compound for organic EL devices represented by Chemical Formula 1 and an organic EL device using the blue light-emitting compound: wherein R1 to R8 each independently represents a functional group selected from the group consisting of hydrogen alkyl groups, alkoxy groups, carbon rings, aryl groups, hetero rings and fused aromatic compounds having from 1 to 30 carbon atoms; to of R1 to R3 may additionally be connected by a ring; and two of R4 to R8 may additionally be connected by a ring.

Abstract: The present invention relates to a blue light-emitting compound for organic polymer EL devices and organic EL devices having superior color purity and light-emitting efficiency by providing a blue light-emitting compound for organic EL devices represented by Chemical Formula 1 and an organic EL device using the blue light-emitting compound: 1

Abstract: The present invention relates to a wavelength converter apparatus for ultra-high speed optical signal process. So, the present invention (a)embodies a wavelength converter which does not need an outer pump light by composing a semiconductor optical amplifier-ring type laser and (b)provides a wavelength converter apparatus for ultra-high speed optical signal process which embodies to be always operated wavelength conversion to be always possible within the amplifying bandwidth(about 40 mm) of SOA by a wavelength-tunable optical band pass filter deposited in a laser resonator.