Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

Abstract: Methods for the in vitro production of enucleated red blood cells and the enucleated red blood cells thus prepared are provided. Such enucleated red blood cells may express a sortaggable surface protein, which allows for surface modification in the presence of a sortase. Also described herein are surface modified enucleated red blood cells, e.g., conjugated with an agent of interest such as a peptide, a detectable label, or a chemotherapeutic agent, and uses thereof in delivering the agent to a subject.

Abstract: Methods and systems for processing additively manufactured objects are provided. In some embodiments, a method includes receiving an object fabricated using an additive manufacturing process, the object including a functional portion and a plurality of support structures connecting the functional portion to a build platform. The method can include cooling the plurality of support structures using a coolant. The method can further include fracturing the plurality of support structures to separate the functional portion of the object from the build platform.

Abstract: A method includes generating an alias that obscures identity information of a user by a remote provider computing system and receiving information relating to a prospective transaction via a digital funding group client application associated with a user computing device and communicatively coupled to the remote provider computing system via a network. The method further includes monitoring a system idle timer of the user computing device and resetting the system idle timer at predetermined time intervals, thereby maintaining the user computing device in active mode. The method further includes, while maintaining the user computing device in active mode, performing an electronic search for a sponsorship opportunity via the network, receiving a search result dataset via the network, generating a displayable result set based on the search result dataset, and rendering the displayable result set on a display. The displayable result set includes at least one prospective sponsor.

Abstract: A cochlear implant including a cochlear lead, an antenna, a stimulation processor, and a magnet apparatus, associated with the antenna, including a case defining a central axis, a magnet frame within the case and rotatable about the central axis of the case, and a plurality of elongate diametrically magnetized magnets that are located in the magnet frame, the magnets defining a longitudinal axis and a N-S direction and being freely rotatable about the longitudinal axis relative to the magnet frame.

Abstract: A surgical instrument system includes a pair of side-specific orthopaedic surgical instrument assemblies. The right-limb side-specific instrument assembly is kitted so as to be devoid of left-limb side-specific instruments and vice versa.

Abstract: A forming tool has an upper portion composed of an upper forming die arranged between a first clamping element and a second clamping element, and a lower portion composed of a lower forming die arranged between a third clamping element and a fourth clamping element. The first clamping element and the third clamping element cooperate to exert a first clamping force on a workpiece; and the second clamping element and the fourth clamping element cooperate to exert a second clamping force on the workpiece. The upper forming die cooperates with the first and second clamping elements and the lower forming die cooperates with the third and fourth clamping elements to exert a lateral force on the workpiece when the first and second clamping forces are being exerted on the workpiece and when a vertical compressive force is being exerted upon the upper forming die and the lower forming die.

Abstract: A water-soluble film, comprising a first water-soluble film, wherein the first water soluble film disintegrates in water within less than about 24 hours and dissolves in water within less than about 48 hours as measured by the MSTM-205 at 20° C. The disclosure provides a water-soluble film comprising a first water-soluble film that disintegrates in water within less than 24 hours and dissolves in water within less than 48 hours as measured by MSTM-205 at 20° C. The first water-soluble film optionally may be further characterized in that it does not disintegrate in water for at least about 1 hour and does not dissolve in water for at least about 1 hour as measured by MSTM-205 at 20° C. The disclosure further provides a water-soluble film comprising a first water-soluble film characterized in that the degradation and/or dissolution of the first water-soluble film is adapted to be activated by consumer handling.

Abstract: An electro-optic device includes a first substrate that has a first surface and a second surface. A second substrate has a third surface and a fourth surface. A first electrode layer is associated with the second surface. A second electrode layer is associated with the third surface. An electro-optic medium is disposed between the first and second electrode layers. The electro-optic medium is operable between substantially activated and substantially unactivated states based on changes to an electrical potential between the first and second electrode layers. At least one third electrode layer is disposed adjacent to one of the first electrode layer and the second electrode layer. At least one light source operably electrically interposes the at least one third electrode layer and the one of the first electrode layer or the second electrode layer that is adjacent to the at least one third electrode layer.

Abstract: This disclosure describes systems and methods for a graphical interface including a graphical representation of medical data. The graphical interface platform may receive medical data and provide medical safety reporting capabilities including reporting of history data and real-time visual monitoring data. The graphical interface platform may be configured to identify potential problems and corrections to medical devices in operation while a reporting cycle is underway through visual representation of performance metrics.

Abstract: A shared-nothing database system is provided in which parallelism and workload balancing are increased by assigning the rows of each table to “slices”, and storing multiple copies (“duplicas”) of each slice across the persistent storage of multiple nodes of the shared-nothing database system. When the data for a table is distributed among the nodes of a shared-nothing system in this manner, requests to read data from a particular row of the table may be handled by any node that stores a duplica of the slice to which the row is assigned. For each slice, a single duplica of the slice is designated as the “primary duplica”. All DML operations (e.g. inserts, deletes, updates, etc.) that target a particular row of the table are performed by the node that has the primary duplica of the slice to which the particular row is assigned. The changes made by the DML operations are then propagated from the primary duplica to the other duplicas (“secondary duplicas”) of the same slice.

Abstract: Embodiments of the present invention are directed to dual threshold voltage (VT) channel devices and their methods of fabrication. In an example, a semiconductor device includes a gate stack disposed on a substrate, the substrate having a first lattice constant. A source region and a drain region are formed on opposite sides of the gate electrode. A channel region is disposed beneath the gate stack and between the source region and the drain region. The source region is disposed in a first recess having a first depth and the drain region disposed in a second recess having a second depth. The first recess is deeper than the second recess. A semiconductor material having a second lattice constant different than the first lattice constant is disposed in the first recess and the second recess.

Abstract: The present disclosure relates to repair devices configured for use in fixing or approximating tissues, such as cardiac valve tissues and particularly the leaflets of a regurgitant mitral valve. The repair device includes a shaft, a pair of proximal elements pivotally coupled to the shaft and extending from the shaft, and a pair of distal elements pivotally coupled to the shaft and extending from the shaft. The proximal and distal elements are configured so that targeted tissue can be grasped therebetween. The distal elements and/or the proximal elements include adjustable arms that can be extended and retracted to adjust the length of the gripping elements to provide more effective grasping of targeted tissues.

Abstract: A portable communication device includes a housing and a push-to-talk button. The push-to-talk (PTT) button is disposed on the front surface of the housing and further occupies a substantial portion of the front surface of the housing. The portable communication device also includes a light emitting diode (LED) stripe that is disposed on the PTT button. The LED stripe is placed on a flexible cable to allow the LED stripe and the PTT button to be moved together when any portion of the front surface of the housing containing the LED stripe and the PTT button is activated. The PTT button is configured to activate transmission of a PTT signal on a talk group channel when the PTT is activated.

Abstract: Systems and methods for accurate and fast measurement of junction temperature for power modules are provided. Such systems and methods include a one or more power transistors that each have a respective die surface over which is positioned and electrically coupled to a conductive overlay. A temperature sensor is physically bonded to a top surface of the conductive overlay to provide a direct temperature measurement for the one or more power transistors.

Abstract: Disclosed herein is a system for time aligning electric power system measurements at an intelligent electronic device (IED) using samples and sample time offset from merging units. The merging units do not require access to a common time signal. The IED does not require storage of a communication latency with the merging units. The sample time offset corresponds to a latency between obtaining the sample and receipt of the sample at the IED. The IED aligns samples from various merging units using sample time offset values communicated from the merging units to the IED. The IED performs monitoring and protection functions using the time aligned samples.

Abstract: Disclosed herein are water-soluble films and resulting packets including a water soluble film, wherein the water-soluble film includes a water-soluble mixture of polyvinyl alcohol, a compatibilizing agent, and a sugar alcohol plasticizer that is a solid at room temperature, wherein the water-soluble film is substantially transparent.

Abstract: The present invention relates to systems and devices for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In particular, the present invention relates to systems and devices for the delivery of energy with heat transfer ability. In some embodiments, the systems and devices also have variable characteristic impedance as a result of the use of heat transfer materials. In certain embodiments, methods are provided for treating a tissue region (e.g., a tumor) through application of energy with the systems and devices of the present invention.

Abstract: A method including the step contacting an olefin, an alcohol, a metallosilicate catalyst and a solvent, wherein the solvent comprises structure (I): wherein R1 and R2 are each selected from the group consisting of an aryl group and an alkyl group with the proviso that at least one of R1 and R2 is an aryl group, further wherein n is 1-3.

Abstract: A thermosetting composition comprising a crosslinkable component such as a vinyl ester and/or an unsaturated polyester, and an initiator component, such as cumene hydroperoxide or BPO or blends of cumene hydroperoxide and methyl ethyl ketone peroxide. The composition is suitable to be used in additive manufacturing to form objects such as molds or prototypes.