Patents by Inventor Léopold THABAULT

Léopold THABAULT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDE INHIBITORS OF LACTATE DEHYDROGENASE ACTIVITY FOR USE IN CANCER THERAPY
    Publication number: 20240116987
    Abstract: A polypeptide including the amino acid sequence of formula (I): GX1MMX2LQHGSX3X4X5QTP. These polypeptides modulate the activity of the native tetrameric lactate dehydrogenase LDH-1, by inhibiting the tetramerization of its subunits. Also, the therapeutic use of these polypeptides as a medicament, in particular for the prevention and/or the treatment of cancer.
    Type: Application
    Filed: February 1, 2022
    Publication date: April 11, 2024
    Applicant: UNIVERSITÉ CATHOLIQUE DE LOUVAIN
    Inventors: Pierre SONVEAUX, Raphaël FREDERICK, Léopold THABAULT, Maxime LIBERELLE
  • LACTATE DEHYDROGENASE INHIBITOR POLYPEPTIDES FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20220289791
    Abstract: A polypeptide that modulates the activity of at least one isoform of the native tetrameric lactate dehydrogenase, and the use thereof as a medicament for the treatment of a cancer. More particularly, linear and cyclic polypeptides that inhibit the tetramerization of the lactate dehydrogenase subunits, and compositions and kits including the polypeptides.
    Type: Application
    Filed: April 30, 2020
    Publication date: September 15, 2022
    Applicant: UNIVERSITÉ CATHOLIQUE DE LOUVAIN
    Inventors: Pierre SONVEAUX, Raphaël FRÉDÉRICK, Léopold THABAULT, Lucie BRISSON, Tamara COPETTI